☆ 4.8 Article

Phosphine Catalysis of the Fluorination of Unactivated Tertiary Alkyl Chlorides under Mild and Convenient Conditions

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Strategies for Nucleophilic C(sp(3))-(Radio)Fluorination

Isabelle Nathalie-Marie Leibler et al.

Summary: This Perspective article provides an overview of the progress and current limitations of nucleophilic fluorination methodologies. Despite the challenges, researchers have been actively studying and developing this transformation to gain a better understanding of its mechanism, create user-friendly fluorination reagents, and contribute to the invention of synthetic methods for radiofluorination. The article discusses studies from the Doyle group and others in the field, highlighting developments in fluoride reagent development and the mechanistic implications of reagent identity. It also outlines the inaccessible chemical space and future directions for filling the existing gaps in synthetic technologies.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2023)

添加到收藏夹

Review Chemistry, Organic

Diethylaminosulfur Trifluoride (DAST) Mediated Transformations Leading to Valuable Building Blocks and Bioactive Compounds

Marcin Kazmierczak et al.

Summary: This minireview focuses on nucleophilic fluorination reactions mediated by diethylaminosulfur trifluoride (DAST) and their applications in synthesizing valuable building blocks and bioactive compounds. Various transformations, including beta-amino alcohols, heterocyclic frameworks synthesis, and rearrangement reactions, are discussed in detail based on literature published since 2010.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Organic

Achievements in fluorination using variable reagents through a deoxyfluorination reaction

Trapti Aggarwal et al.

Summary: This review summarizes the progress made in the field of deoxyfluorination for the construction of biologically active molecules from 2011 to 2021. The development of novel reagents has enabled new mechanistic approaches to achieve organic transformations. The fusion of fluorine in drug molecules remains an important research area due to its presence in numerous pharmaceutical active ingredients.

ORGANIC CHEMISTRY FRONTIERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent Advances in the Application of Selectfluor as a Fluorine-free Functional Reagent in Organic Synthesis

Ke Yang et al.

CHEMISTRY-AN ASIAN JOURNAL (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Contribution of Organofluorine Compounds to Pharmaceuticals

Munenori Inoue et al.

ACS OMEGA (2020)

添加到收藏夹

Article Chemistry, Organic

Dehydroxylative Fluorination of Tertiary Alcohols

Wei Zhang et al.

ORGANIC LETTERS (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Catalytic C(sp3)-F bond formation: recent achievements and pertaining challenges

Giulia Tarantino et al.

GREEN CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Open-Shell Fluorination of Alkyl Bromides: Unexpected Selectivity in a Silyl Radical-Mediated Chain Process

Gabrielle H. Lovett et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

添加到收藏夹

Article Chemistry, Physical

Palladium-Catalyzed Synthesis of α-Trifluoromethyl Benzylic Amines via Fluoroarylation of gem-Difluoro-2-azadienes Enabled by Phosphine-Catalyzed Formation of an Azaallyl-Silver Intermediate

Paige E. Daniel et al.

ACS CATALYSIS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Selective Radical Fluorination of Tertiary Alkyl Halides at Room Temperature

He Chen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Monofluorination of Organic Compounds: 10 Years of Innovation

Pier Alexandre Champagne et al.

CHEMICAL REVIEWS (2015)

添加到收藏夹

Article Chemistry, Organic

An Efficient Difluorohydroxylation of Indoles Using Selectfluor as a Fluorinating Reagent

Riyuan Lin et al.

ORGANIC LETTERS (2011)

添加到收藏夹

Article Chemistry, Applied

Selective Preparation of Diamondoid Fluorides

Hartmut Schwertfeger et al.

ADVANCED SYNTHESIS & CATALYSIS (2009)

添加到收藏夹

Review Chemistry, Inorganic & Nuclear

Coordination complexes of silver(I) with tertiary phosphine and related ligands

Reinout Meijboom et al.

COORDINATION CHEMISTRY REVIEWS (2009)

添加到收藏夹

Article Chemistry, Organic

Stereocontrolled synthesis of (S)-γ-fluoroleucine

Dharshana Padmakshan et al.

SYNLETT (2007)

添加到收藏夹

Article Chemistry, Organic

An efficient method for the cleavage of p-methoxybenzylidene (PMP), tetrahydropyranyl (THP) and 1,3-dithiane protecting groups by Selectfluor™

JJ Liu et al.

TETRAHEDRON LETTERS (2002)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Catalytic fluorination by halide exchange with 16-electron ruthenium(II) complexes.: X-ray structure of [Tl(μ-F)2Ru(dppe)2]PF6

P Barthazy et al.

ORGANOMETALLICS (2001)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.