3.8 Article

Racial, Ethnic, and Gender Diversity in United States Ophthalmology Clinical Trials

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Ophthalmology

Racial and Ethnic Disparities in Dry Eye Diagnosis and Care

David Cui et al.

Summary: The purpose of this study was to investigate health disparities in racial and ethnic minorities with dry eye. The study found that minorities had worse objective dry eye parameters and less prior dry eye care. They also had lower household income and less access to healthcare. The findings suggest that differential management by eye care providers and patient attitudes may contribute to these disparities.

OPHTHALMIC EPIDEMIOLOGY (2023)

Article Medicine, General & Internal

Disparity in the selection of patients in clinical trials

Farrokh Habibzadeh

LANCET (2022)

Editorial Material Oncology

Editorial: Disparities in Cancer Prevention and Epidemiology

Fateme Montazeri et al.

FRONTIERS IN ONCOLOGY (2022)

Editorial Material Ophthalmology

Representation Matters-Diversity in Retina Clinical Trials

Sally L. Baxter

JAMA OPHTHALMOLOGY (2022)

Article Ophthalmology

Representation of Race and Ethnicity in Randomized Clinical Trials of Diabetic Macular Edema and Retinal Vein Occlusion Compared to 2010 US Census Data

Abdul-Hadi Kaakour et al.

Summary: This study compared the racial and ethnic distribution in randomized clinical trials (RCTs) of diabetic macular edema (DME) and macular edema from retinal vein occlusion (RVO) to the US Census data. The findings revealed a discrepancy between the RCTs and the US population, with overrepresentation of White participants and underrepresentation of Hispanic participants. These findings emphasize the need to recruit underrepresented racial and ethnic minorities to improve the external validity of trial results.

JAMA OPHTHALMOLOGY (2022)

Review Endocrinology & Metabolism

The roles of sex and gender in women's eye health disparities in the United States

Irene O. Aninye et al.

Summary: In the United States, women are at a higher risk of developing vision impairment or serious eye diseases compared to men, with disparities in eye health due to both biological and social determinants. The expert working group recommended a systematic approach with a focus on gender disparities, as well as increasing education for healthcare providers and the public to reduce inequalities and improve patient care in women's eye health.

BIOLOGY OF SEX DIFFERENCES (2021)

Article Ophthalmology

Racial/Ethnic Disparities in Ophthalmology Clinical Trials Resulting in US Food and Drug Administration Drug Approvals From 2000 to 2020

Sean T. Berkowitz et al.

Summary: This study evaluated the racial representation in clinical trials leading to FDA drug approvals in ophthalmology from 2000 to 2020, finding that Black, Hispanic or Latinx, and other non-White participants were underrepresented compared to the expected distribution in the US. Despite improvements from 2000 to 2020, further efforts are needed to increase minority enrollment in clinical trials.

JAMA OPHTHALMOLOGY (2021)

Review Medicine, General & Internal

Racial and Ethnic Disparities in Primary Open-Angle Glaucoma Clinical Trials A Systematic Review and Meta-analysis

Karen Allison et al.

Summary: This study found that compared to White individuals, individuals from racial/ethnic minority groups had a very low participation rate in primary open-angle glaucoma (POAG) clinical trials despite higher prevalence among the disease population. Despite efforts to increase diversity, there was no significant increase in clinical trial participation among Black individuals, the most affected group by POAG. This disparity raises questions about the safety and efficacy of medical interventions for POAG and underscores the need for further research on enhancing diversity in clinical trials for this disease.

JAMA NETWORK OPEN (2021)

Article Gastroenterology & Hepatology

Diversity in clinical trials: an opportunity and imperative for community engagement

Darrell M Gray et al.

Lancet Gastroenterology & Hepatology (2021)

Article Medicine, General & Internal

Analysis of Female Enrollment and Participant Sex by Burden of Disease in US Clinical Trials Between 2000 and 2020

Jecca R. Steinberg et al.

Summary: This study found that sex differences in clinical trials varied by disease category, with male and female participants underrepresented in different medical fields. Although progress has been made in sex equity, the persistence of sex bias in clinical trials within medical fields has negative consequences for the health of all individuals.

JAMA NETWORK OPEN (2021)

Article Ophthalmology

Reporting of Race and Ethnicity in the Ophthalmology Literature in 2019

Daniel B. Moore

JAMA OPHTHALMOLOGY (2020)

Editorial Material Medicine, General & Internal

Raising the profile of men's health

[Anonymous]

LANCET (2019)

Article Health Care Sciences & Services

Racial/Ethnic and Gender Disparities in Health Care Use and Access

Jennifer I. Manuel

HEALTH SERVICES RESEARCH (2018)

Review Medicine, General & Internal

Increasing value and reducing waste in biomedical research: who's listening?

David Moher et al.

LANCET (2016)

Article Public, Environmental & Occupational Health

Twenty years and still counting: including women as participants and studying sex and gender in biomedical research

Carolyn M. Mazure et al.

BMC WOMENS HEALTH (2015)

Article Nursing

Lessons learned: Research with rural Mexican-American women

A Mann et al.

NURSING OUTLOOK (2005)