☆ 4.2 Review

Multidisciplinary Rehabilitation after Hyaluronic Acid Injections for Elderly with Knee, Hip, Shoulder, and Temporomandibular Joint Osteoarthritis

MEDICINA-LITHUANIA (2023)

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Summary: This study evaluated the association between temporomandibular disorder (TMD) and neck pain in patients with primary headaches. The results showed that migraine patients reported higher TMD and neck pain. Machine learning analysis demonstrated that TMD was correlated to migraine, while neck pain was correlated to tension-type headache (TTH) or migraine.

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Summary: This study examines the trends in the burden of osteoarthritis (OA) in Australia from 1990 to 2019 and compares it with other common conditions associated with older age. The results show a significant growth in the prevalence of OA and the associated disability. The burden of OA is higher than other common health conditions, highlighting the need for enhanced prevention and management.

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Martina Ferrillo et al.

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Giuseppe Minervini et al.

Summary: Temporomandibular disorders (TMDs) are a common and debilitating condition, and their exact causes remain unclear. Besides genetic, injury, and stress factors, socioeconomic status (SES) may also play a role in TMD development. This review aims to provide a comprehensive understanding of the role of SES in TMDs and inform the development of targeted interventions.

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Review Orthopedics

Efficacy of intra-articular injections of hyaluronic acid in patients with glenohumeral joint osteoarthritis: A systematic review and meta-analysis

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Summary: This systematic review and meta-analysis aimed to evaluate the efficacy of intra-articular hyaluronic acid (HA) on pain relief for patients with glenohumeral joint osteoarthritis (GH-OA). The analysis of 15 studies showed that HA injections combined with physical therapy were more effective in relieving pain compared to physical therapy alone, and were superior to corticosteroid injections. Overall, the study received a score of 7 out of 10.

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Effects of proprioceptive neuromuscular facilitation stretching in relieving pain and balancing knee loading during stepping over obstacles among older adults with knee osteoarthritis: A randomized controlled trial

Bo Gao et al.

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PLOS ONE (2023)

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Article Dentistry, Oral Surgery & Medicine

Short term effects of a novel combined approach compared with physical therapy alone among older patients with temporomandibular degenerative joint disease: a prospective cohort study

Shasha Liu et al.

Summary: This study aimed to investigate the optimal treatment option, including physical exercise, for older patients with temporomandibular degenerative joint disease (DJD). The results showed that compared to physical therapy alone, the combined approach of injection and home physical exercise significantly improved pain while opening the mouth within 12 weeks, and required fewer visits. On the other hand, physical therapy improved the patients' mouth-opening capabilities in a short time (2 weeks).

BMC ORAL HEALTH (2023)

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Hyaluronic acid injections for pain relief and functional improvement in patients with temporomandibular disorders: An umbrella review of systematic reviews

Francesco Agostini et al.

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Review Dentistry, Oral Surgery & Medicine

Comparative effectiveness of hyaluronic acid, platelet-rich plasma, and platelet-rich fibrin in treating temporomandibular disorders: a systematic review and network meta-analysis

Jingjing Xu et al.

Summary: This study compared the efficacy of hyaluronic acid (HA), platelet-rich plasma (PRP), and platelet-rich fibrin (PRF) in treating temporomandibular disorders (TMDs) and summarized their mechanisms of action. The findings indicated that PRP and PRF had similar short-term efficacy, but PRF was more advantageous in terms of long-term efficacy.

HEAD & FACE MEDICINE (2023)

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Shuaifei Ji et al.

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SIGNAL TRANSDUCTION AND TARGETED THERAPY (2023)

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Virtual Tools to Enable Management of Knee Osteoarthritis

Rana S. Hinman et al.

Summary: Virtual tools, such as telephone, videoconferencing, websites, internet-delivered programs, SMS, and mobile applications, can improve access to knee osteoarthritis (OA) management. There is increasing evidence supporting the clinical effectiveness and acceptability of virtual tools, but there are barriers to their use that need to be addressed for successful implementation in clinical settings.

CURRENT TREATMENT OPTIONS IN RHEUMATOLOGY (2023)

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Review Orthopedics

Risk analysis of periprosthetic knee joint infection (PJI) in total knee arthroplasty after preoperative corticosteroid injection: a systematic review A study performed by the Early-Osteoarthritis group of ESSKA-European Knee Associates section

M. H. Baums et al.

Summary: This study investigates whether preoperative intra-articular corticosteroid injection increases the risk of post-operative periprosthetic joint infection (PJI) in total knee arthroplasty (TKA) patients. The results show that intra-articular corticosteroid injections within 3 months prior to TKA are associated with a significantly increased risk of infection.

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY (2023)

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Hyaluronic acid injection to restore the lost interproximal papilla: a systematic review

Adriana Castro-Calderon et al.

Summary: The study assessed the efficacy and safety of hyaluronic acid (HA) injections for restoring lost interproximal papilla. Non-surgical use of HA injections showed positive effects on reestablishing lost interproximal papilla, although post-operative complications may occur.

ACTA ODONTOLOGICA SCANDINAVICA (2022)

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Review Orthopedics

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AAOS Clinical Practice Guideline Summary: Management of Osteoarthritis of the Knee (Nonarthroplasty), Third Edition

Robert H. Brophy et al.

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Epidemiology of osteoarthritis

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OSTEOARTHRITIS AND CARTILAGE (2022)

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Review Orthopedics

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Donald G. Manlapaz et al.

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Marco Invernizzi et al.

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Ji-Ah Song et al.

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HEALTHCARE (2022)

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Therapeutic Exercise and Conservative Injection Treatment for Early Knee Osteoarthritis in Athletes: A Scoping Review

Lucrezia Tognolo et al.

Summary: Therapeutic exercise, intra-articular viscosupplementation with Hyaluronic Acid, and Platelet Rich Plasma treatment have been found to have beneficial effects on preventing cartilage degeneration, reducing pain, and enhancing physical function in the conservative management of early knee osteoarthritis. A multimodal treatment combining therapeutic exercise and moderate aerobic activity is indicated to prevent kOA development, while minimally invasive injection therapy can contribute to improving motor function and symptomatology in symptomatic cases.

MEDICINA-LITHUANIA (2022)

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Association between Kinesiophobia and Knee Pain Intensity, Joint Position Sense, and Functional Performance in Individuals with Bilateral Knee Osteoarthritis

Mastour Saeed Alshahrani et al.

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HEALTHCARE (2022)

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Chris McGibbon et al.

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Injection route affects intra-articular hyaluronic acid distribution and clinical outcome in viscosupplementation treatment for knee osteoarthritis: a combined cadaver study and randomized clinical trial

Jun Xiao et al.

Summary: Hyaluronic acid coverage on the impaired cartilage is crucial for its beneficial effect on knee osteoarthritis, with distribution in different joints affected by the route of drug delivery. Intra-articular injection of HA through the medial midpatellar route showed superior clinical efficacy and cartilage coverage compared to the anteromedial route in treating mild-to-moderate KOA.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2021)

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Review Orthopedics

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Gerardo Fusco et al.

Summary: Knee osteoarthritis can be treated with injection therapies such as hyaluronic acid and cortico-steroids, as well as promising products like polydeoxyribonucleotide and biologic agents. While biological products have strong in vitro evidence, there is still a lack of robust clinical evidence for their effectiveness in treating OA symptoms. Emerging treatments including combined biological therapies and nano-molecular approaches are currently under development to expand the options for knee OA treatment.

EFORT OPEN REVIEWS (2021)

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JNP-JOURNAL FOR NURSE PRACTITIONERS (2021)

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Non-surgical osteoarthritis therapy, intra-articular drug delivery towards clinical applications

Yujie Liang et al.

Summary: Intra-articular drug delivery is a conservative treatment method that improves the bioavailability of therapeutic composites in OA joint cavity. New targeted nano-based drug delivery systems and gene delivery for OA therapy show promising prospects.

JOURNAL OF DRUG TARGETING (2021)

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Leena Sharma

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NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Review Dentistry, Oral Surgery & Medicine

Is there a difference in treatment effect of different intra-articular drugs for temporomandibular joint osteoarthritis? A systematic review of randomized controlled trials

A. Liapaki et al.

Summary: In patients with TMJOA, injectables in conjunction with arthrocentesis were found to be effective in alleviating pain and improving MMO. PRGF/PRP injections were more effective than HA. In terms of MMO improvement, arthrocentesis + PRP was superior to arthrocentesis + HA.

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY (2021)

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Review Environmental Sciences

Telehealth Use in Geriatrics Care during the COVID-19 Pandemic-A Scoping Review and Evidence Synthesis

Sathyanarayanan Doraiswamy et al.

Summary: Telehealth in geriatric care shows strengths in convenience and affordability, weaknesses in meeting specific physical and cognitive limitations, threats of inequity and lack of standardization, and opportunities in technologic advancements driven by simplicity and user-friendliness for older people. Optimizing telehealth services for older people requires greater government investments and active engagement by a broader participation of stakeholders.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Sasha Elbaz et al.

Summary: This systematic review aimed to explore the use, accessibility, and feasibility of telemedicine in older adults with dementia, as well as examine the potential mental health impacts of these technologies, through reviewing evidence from studies conducted during COVID-19. Despite the barriers, telemedicine was noted as a feasible approach to assist individuals with dementia in connecting with their service providers and family while reducing complications related to travel. Due to the COVID-19 pandemic, finding alternative ways to provide services to older adults with dementia through technology may continue to become more necessary as time goes on.

FRONTIERS IN NEUROLOGY (2021)

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Hyaluronic Acid: A Key Ingredient in the Therapy of Inflammation

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BIOMOLECULES (2021)

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Injection-Based Management of Osteoarthritis of the Knee: A Systematic Review of Guidelines

Vito Pavone et al.

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FRONTIERS IN PHARMACOLOGY (2021)

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Preoperative Nonsurgical Weight Loss Interventions Before Total Hip and Knee Arthroplasty: A Systematic Review

Michael W. Seward et al.

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Molecular Weight of Hyaluronic Acid Has Major Influence on Its Efficacy and Safety for Viscosupplementation in Hip Osteoarthritis: A Systematic Review and Meta-Analysis

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CARTILAGE (2021)

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A Systematic Review of Current Clinical Practice Guidelines on Intra-articular Hyaluronic Acid, Corticosteroid, and Platelet-Rich Plasma Injection for Knee Osteoarthritis: An International Perspective

Mark Phillips et al.

Summary: This study reviewed the role of injections in nonoperative management of knee osteoarthritis, focusing on intra-articular hyaluronic acid, intra-articular corticosteroids, and platelet-rich plasma. It found that most guidelines support the use of intra-articular hyaluronic acid and intra-articular corticosteroids for symptom relief in knee osteoarthritis.

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Jacquelin Peck et al.

Summary: Osteoarthritis (OA) is the most common form of arthritis in the US, affecting 22.7% of the adult population. Knee is the most commonly affected joint, followed by hands and hips. Treatment modalities include weight control, exercise, anti-inflammatory drugs, intra-articular platelet-rich plasma, corticosteroid injection, viscosupplementation, and surgery.

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A matrix metalloproteinase-generated neoepitope of CRP can identify knee and multi-joint inflammation in osteoarthritis

Louie C. Alexander et al.

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Differentiating factors of intra-articular injectables have a meaningful impact on knee osteoarthritis outcomes: a network meta-analysis

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