Attention deficits and depressive symptoms improve differentially after rehabilitation of post-COVID condition - A prospective cohort study

Editorial Material Psychiatry

Why the hypothesis of psychological mechanisms in long COVID is worth considering

Cedric Lemogne et al.

JOURNAL OF PSYCHOSOMATIC RESEARCH (2023)

Article Immunology

Association of cerebrospinal fluid brain-binding autoantibodies with cognitive impairment in post-COVID-19 syndrome

Christiana Franke et al.

Summary: Autoantibodies targeting brain epitopes are common in patients with post-COVID-19 syndrome (PCS) and strongly associate with pathological cognitive screening tests, particularly when found in cerebrospinal fluid (CSF).

BRAIN BEHAVIOR AND IMMUNITY (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Cognitive impairment in young adults with post COVID-19 syndrome

Elena Herrera et al.

Summary: This study aimed to examine cognitive domains in a large sample of post COVID-19 syndrome patients. A total of 214 patients, 85.04% women, aged 26 to 64 years (mean = 47.48 years), participated in the investigation. Tests assessing processing speed, attention, executive functions, and language modalities indicated alterations in tasks for 85% of the participants, with attention and executive functions showing the highest percentage of severe impairment. Age was found to have a positive correlation with performance, with older patients maintaining relatively preserved cognitive functions compared to younger patients who exhibited more pronounced and diverse cognitive impairments.

SCIENTIFIC REPORTS (2023)

添加到收藏夹

Article Neurosciences

What do we mean by long COVID? A scoping review of the cognitive sequelae of SARS‐CoV‐2 infection

Alessia Nicotra et al.

EUROPEAN JOURNAL OF NEUROLOGY (2023)

添加到收藏夹

Article Rehabilitation

First results from post-COVID inpatient rehabilitation

Alexa Kupferschmitt et al.

Summary: This study compared the psychological stress and rehabilitation outcomes of post-COVID patients with psychosomatic and psychocardiological patients. The results showed that post-COVID patients had a milder psychological burden compared to psychosomatic and psychocardiological patients. During rehabilitation, the symptom severity significantly decreased in post-COVID patients, and improvements were seen in self-efficacy and activity participation.

FRONTIERS IN REHABILITATION SCIENCES (2023)

添加到收藏夹

Article Medicine, General & Internal

The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome

Ravindra Ganesh et al.

Summary: This study described the clinical data from the first 108 patients seen in the Mayo Clinic post-COVID-19 care clinic (PCOCC). Several distinct clinical phenotypes were observed, with the fatigue predominant phenotype being the most common and associated with female sex and elevated IL-6 levels.

MAYO CLINIC PROCEEDINGS (2022)

添加到收藏夹

Article Public, Environmental & Occupational Health

Return to work after COVID-19 infection- A Danish nationwide registry study

P. A. Jacobsen et al.

Summary: This study aimed to investigate the return to work after COVID-19 and how the severity of the disease affects it. The study found that hospitalized patients have a lower chance of returning to work, and factors such as female sex, older age, and comorbidity are associated with a lower chance of returning to work.

PUBLIC HEALTH (2022)

添加到收藏夹

Review Multidisciplinary Sciences

Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue syndrome

Olga A. Sukocheva et al.

Summary: COVID-19 infection can lead to various pathologies and complications, exacerbating existing conditions in multiple body systems. Besides the respiratory organs, adverse effects of COVID-19 have been observed in the nervous, cardiovascular, gastrointestinal/metabolic, immune, and other systems. The post-COVID-19 condition shows overlapping symptoms with ME/CFS.

JOURNAL OF ADVANCED RESEARCH (2022)

添加到收藏夹

Review Clinical Neurology

Changes in cognitive functioning after COVID-19: A systematic review and meta-analysis

Lucia Crivelli et al.

Summary: This study conducted a systematic review and meta-analysis on the cognitive effects of COVID-19 in adults without prior cognitive impairment. The results showed that post-COVID-19 patients experienced impairments in executive functions, attention, and memory. A meta-analysis comparing recovered COVID-19 patients and healthy controls demonstrated lower general cognition in the post-infection period up to 7 months.

ALZHEIMERS & DEMENTIA (2022)

添加到收藏夹

Review Immunology

Fatigue and cognitive impairment in Post-COVID-19 Syndrome: A systematic review and meta-analysis

Felicia Ceban et al.

Summary: Post-COVID-19 syndrome, characterized by persistent symptoms after resolution of acute infection, is associated with significant fatigue and cognitive impairment. This study aimed to quantify the proportion of individuals experiencing fatigue and cognitive impairment 12 or more weeks after COVID-19 diagnosis, and to explore the inflammatory and functional consequences of post-COVID-19 syndrome. The results showed that a significant proportion of individuals continue to experience fatigue and cognitive impairment even after 12 or more weeks of COVID-19 diagnosis. Additionally, some individuals showed elevated levels of inflammatory markers and significant functional impairment.

BRAIN BEHAVIOR AND IMMUNITY (2022)

添加到收藏夹

Article Clinical Neurology

Post-COVID-19 fatigue: the contribution of cognitive and neuropsychiatric symptoms

Marco Calabria et al.

Summary: Fatigue is a common symptom of post-COVID-19 condition and is often accompanied by cognitive dysfunction and neuropsychiatric symptoms. This study found that different types of fatigue were predicted by apathy, anxiety, executive dysfunction, and attentional difficulties, suggesting the importance of considering holistic treatment approaches for COVID-19 patients experiencing fatigue.

JOURNAL OF NEUROLOGY (2022)

添加到收藏夹

Review Clinical Neurology

Post-COVID-19 Depressive Symptoms: Epidemiology, Pathophysiology, and Pharmacological Treatment

Mario Gennaro Mazza et al.

Summary: Depression, anxiety, and cognitive impairments are recognized as primary symptoms of the post-acute COVID-19 syndrome in survivors. Depressive symptoms after COVID-19 can affect neurocognitive functioning, sleep, quality of life, and global functioning. The underlying mechanisms are related to inflammation triggered by the immune response to the viral infection and persistent psychological burden. Screening, diagnosing, treating, and monitoring the psychopathology of COVID-19 survivors is essential to counteract the burden and disability caused by depression.

CNS DRUGS (2022)

添加到收藏夹

Review Behavioral Sciences

Cognitive impairment in people with previous COVID-19 infection: A scoping review

Margherita Bertuccelli et al.

Summary: A scoping review was conducted to map cognitive domain impairments and associated psycho-affective disorders in COVID-19 survivors. Memory, attention, and executive functions were found to be the most affected domains, while language and visuo-spatial abilities were less impacted. Reports also showed a frequent association between neurological and respiratory conditions with cognitive deficits, but inconclusive results on psycho-affective conditions.

CORTEX (2022)

添加到收藏夹

Article Psychology, Multidisciplinary

Relevance of the post-COVID syndrome within rehabilitation (PoCoRe): study protocol of a multi-centre study with different specialisations

Alexa Kupferschmitt et al.

Summary: This study aims to describe different functional impairments in COVID-19 rehabilitation patients and evaluate the effectiveness of specific rehabilitation measures. The study will be conducted in seven rehabilitation clinics of different specializations and will include 1000 cases. The findings of the study will contribute to improving the rehabilitation treatment and quality of life for post-COVID-19 patients.

BMC PSYCHOLOGY (2022)

添加到收藏夹

Article Respiratory System

S1 Guideline Post-COVID/Long-COVID

Andreas Rembert Koczulla et al.

Summary: The guideline on Post-COVID/Long-COVID initiated by the German Society of Pneumology is designed in a broad interdisciplinary approach based on current knowledge. It describes current symptoms, diagnostic approaches, and therapies with a specific focus and practical claim for continuous development and adaptation by the author team.

PNEUMOLOGIE (2021)

添加到收藏夹

Article Neurosciences

Long-Lasting Cognitive Abnormalities after COVID-19

Roberta Ferrucci et al.

Summary: Cognitive abnormalities were frequently found in COVID-19 patients 5 months after hospital discharge, with some experiencing deficits in processing speed and verbal memory. Bivariate analysis indicated a positive correlation between factors like arterial oxygen partial pressure, fractional inspired oxygen ratio, and SpO2 levels during hospitalization, and verbal memory performance.

BRAIN SCIENCES (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Post-acute COVID-19 syndrome

Ani Nalbandian et al.

Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.

NATURE MEDICINE (2021)

添加到收藏夹

Review Biology

Depressive and Neurocognitive Disorders in the Context of the Inflammatory Background of COVID-19

Eliza Dabrowska et al.

Summary: The impact of COVID-19 infection on the nervous system is characterized by neuroinflammation, depressive symptoms, and potential long-term effects. Research suggests that the immune response to the virus and pandemic-related stress may lead to chronic inflammatory processes. Symptoms of post-COVID-19 syndrome can persist for weeks. Fluoxetine, an SSRI antidepressant, shows promise in combating COVID-19. Continued research is crucial to understanding the pathomechanism of SARS-CoV-2 infection and its neuropsychiatric effects.

LIFE-BASEL (2021)

添加到收藏夹

Editorial Material Psychiatry

Psychiatric symptoms and cognitive impairment in Long COVID: the relevance of immunopsychiatry

Brenda W. J. H. Penninx

WORLD PSYCHIATRY (2021)

添加到收藏夹

Review Medicine, General & Internal

Biomarkers of Post-COVID Depression

Piotr Lorkiewicz et al.

Summary: Research indicates that the development of post-COVID depression may be similar to the pathophysiology of MDD, and the identification of biomarkers can help in quicker diagnosis and effective treatment of affected patients.

JOURNAL OF CLINICAL MEDICINE (2021)

添加到收藏夹

Article Sport Sciences