4.8 Article

Biomimetic nanoplatform with anti-inflammation and neuroprotective effects for repairing spinal cord injury in mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Materials Science, Biomaterials

Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Yuanyuan Ding et al.

Summary: Reactive oxygen species (ROS) have been recognized as a potential therapeutic target in cancer treatment, and various strategies and technologies have been explored to increase ROS levels in tumor tissues, including delivery of enzymes, nanozymes, biological molecules, Fenton-reagents, and modulation of antioxidant substances and input of mechanical and electromagnetic waves. These ROS-upregulating systems have shown promise in enhancing and synergizing cancer therapies such as chemotherapy, chemodynamic therapy, phototherapy, and immunotherapy. However, there are still challenges to overcome and future studies are needed to further advance this field.

BIOMATERIALS SCIENCE (2023)

Article Cell Biology

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

Helmut Sies et al.

Summary: This article discusses the key issues associated with identifying the physiological roles of oxidants, with a focus on H2O2 and O-2(.-). The article emphasizes the need for more precise measurement of oxidants and specific identification of their signaling targets. It also highlights the importance of inter-organellar communication and the contribution of environmental exposures. Development of tools for real-time detection and quantification of individual oxidants is crucial for achieving these goals.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)

Review Immunology

Reactive Oxygen Species in Macrophages: Sources and Targets

Marcella Canton et al.

Summary: Reactive oxygen species (ROS) are essential for macrophages to eliminate microorganisms, but also play roles in signal transduction, differentiation, and gene expression; different outcomes may result from ROS formation in specific subcellular sites; identifying the intracellular sources of ROS and their impact on cellular processes is crucial for developing therapies targeting oxidative signaling networks.

FRONTIERS IN IMMUNOLOGY (2021)

Article Clinical Neurology

Acute Traumatic Spinal Cord Injury

Ilyas Eli et al.

NEUROLOGIC CLINICS (2021)

Review Pharmacology & Pharmacy

Celastrol in metabolic diseases: Progress and application prospects

Shaohua Xu et al.

Summary: Celastrol, as an active ingredient derived from plants, has shown great potential in the treatment of metabolic diseases. Its anti-obesity effect is achieved through regulating various aspects, and it also shows effects on diseases like diabetes, atherosclerosis, and osteoporosis.

PHARMACOLOGICAL RESEARCH (2021)

Review Materials Science, Biomaterials

Recent progress in nanotechnology-based drug carriers for celastrol delivery

Ling Guo et al.

Summary: Celastrol, an active ingredient from Tripterygium wilfordii, has demonstrated potential pharmacological activities in various diseases, but its clinical application is limited by low bioavailability and toxicity. Nanotechnology offers a solution to enhance the utilization of Celastrol.

BIOMATERIALS SCIENCE (2021)

Article Nanoscience & Nanotechnology

Poly(lactic-co-glycolic) Acid-Lipid Hybrid Microparticles Enhance the Intracellular Uptake and Antibacterial Activity of Rifampicin

Sajedeh Maghrebi et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Nanoscience & Nanotechnology

Y Selenium-Doped Carbon Quantum Dots Efficiently Ameliorate Secondary Spinal Cord Injury via Scavenging Reactive Oxygen Species

Wenqi Luo et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Chemistry, Multidisciplinary

A Nanozyme with Photo-Enhanced Dual Enzyme-Like Activities for Deep Pancreatic Cancer Therapy

Shanshan Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Review Clinical Neurology

The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration

Thomas H. Hutson et al.

NATURE REVIEWS NEUROLOGY (2019)

Review Chemistry, Multidisciplinary

Crossing the blood-brain barrier with nanoparticles

Yiqun Zhou et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Article Multidisciplinary Sciences

NT3-chitosan enables de novo regeneration and functional recovery in monkeys after spinal cord injury

Jia-Sheng Rao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Review Pharmacology & Pharmacy

A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F

Shao-Ru Chen et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Cell & Tissue Engineering

Spinal Cord Regeneration

Wise Young

CELL TRANSPLANTATION (2014)

Review Chemistry, Multidisciplinary

PLGA-based nanoparticles: An overview of biomedical applications

Fabienne Danhier et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Review Medicine, General & Internal

Spinal-cord injury

JW McDonald et al.

LANCET (2002)

Review Clinical Neurology

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

AC Allison et al.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2001)