Occurrence and bioaccumulation of parabens and their metabolites in the biota from a subtropical freshwater river ecosystem: Implications for human exposure

Widespread occurrence of parabens in the environment has been documented, whereas little information is available about the occurrence and bioaccumulation of parabens in the aquatic biota. In this study, plants (n = 14), plankton (n = 20), and fish muscle (n = 89) samples were collected from Dongjiang River Basin and analyzed for nine parabens and two of their metabolites using ultra-high performance liquid chromatogramtandem mass spectrometry. All the samples contained notable concentrations of parabens and the metabolites, and the total concentrations of parabens (sigma p-PBs; sum of nine parent compounds) ranged from 0.40 to 776 ng/g dry wt. MeP, EtP, and PrP were the predominant parent compounds in both plankton and fish, while in plants, MeP, BzP and EtP were the top three abundant chemicals. As the predominant metabolite, 4-HB was detected in 99% aquatic biota samples analyzed with the highest concentration (24800 ng/g, dry wt) detected in an alga. Significantly positively correlations among the concentrations of MeP, BzP, EtP and 4-HB in the fish muscle were found. Based on dry weight, bioaccumulation potentials of these chemical substances were estimated with bioaccumulation factor (BAF) values greater than 2000 L/kg, suggestive of bioaccumulative in aquatic biota. Based on the concentrations measured, the estimated daily intakes (EDIs) of parabens through fish consumption were estimated with the mean EDIs being 4.20, 2.41, and 1.93 ng/kg bw/day for toddlers, children, and adults in urban, respectively. This study provides baseline information about the occurrence and fate of parabens in the aquatic environment.

Automated summary

This study investigated the occurrence and bioaccumulation of parabens in the aquatic environment, specifically in the Dongjiang River Basin. The results showed that parabens were widely present in the samples and exhibited bioaccumulation potential. Additionally, the study estimated the daily intake of parabens through fish consumption.