☆ 4.4 Review

Nanocarrier-mediated curcumin delivery: An adjuvant strategy for CNS disease treatment

EXPERIMENTAL BIOLOGY AND MEDICINE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Neurosciences

The effects of nano-curcumin supplementation on Th2/tregulatory axis in migraine patients: a randomized, double-blind, placebo-controlled trial

Mona Djalali et al.

Summary: This study investigated the effects of nano-curcumin supplementation on gene expression and serum levels of IL-4 and TGF-beta in migraine patients. The results showed that nano-curcumin treatment significantly increased IL-4 levels, but had minimal effects on TGF-beta gene expression and serum levels.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2023)

添加到收藏夹

Article Cell Biology

Curcumin-loaded human endometrial stem cells derived exosomes as an effective carrier to suppress alpha-synuclein aggregates in 6OHDA-induced Parkinson's disease mouse model

Mahsa Mobahat et al.

Summary: This study successfully enhanced the penetration of curcumin through the blood brain barrier into the brain by fabricating nanoformulated curcumin loaded exosomes. The new formulation improved the anti-Parkinsonism effects of curcumin, including suppressing alpha-synuclein aggregation and rescuing neuronal cell death.

CELL AND TISSUE BANKING (2023)

添加到收藏夹

Article Endocrinology & Metabolism

Curcumin-resveratrol nano-formulation counteracting hyperammonemia in rats

Maha Nasr et al.

Summary: Malnutrition and low dietary protein intake can lead to peripheral and central hyperammonemia, particularly in pediatrics. Curcumin and resveratrol have shown effectiveness against liver and brain injuries, but their bioavailability is low. This study investigated the use of a nanoemulsion formulation containing both curcumin and resveratrol in ameliorating protein-deficient diet-induced hyperammonemia in rats. The results demonstrated that the nanoemulsion effectively reduced ammonia levels, oxidative damage, and improved cellular energy performance in the liver and brain.

METABOLIC BRAIN DISEASE (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin-Loaded Mesenchymal Stem Cell-Derived Exosomes Efficiently Attenuate Proliferation and Inflammatory Response in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Xinghong He et al.

Summary: This study evaluated the potential of mesenchymal stem cell-derived exosomes loaded with curcumin (Curc-Exos) as a therapeutic strategy for rheumatoid arthritis. Curc-Exos exhibited improved stability compared to free curcumin. In vitro studies showed that Curc-Exos enhanced cytotoxicity and apoptosis in HIG-82 synovial cells, and reduced the expression of anti-apoptotic proteins and inflammatory mediators. This preliminary study demonstrates the suitability of Curc-Exos in counteracting the proliferation and inflammatory response in rheumatoid arthritis synovial fibroblasts.

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Three months of combination therapy with nano-curcumin reduces the inflammation and lipoprotein (a) in type 2 diabetic patients with mild to moderate coronary artery disease: Evidence of a randomized, double-blinded, placebo-controlled clinical trial

Mostafa Dastani et al.

Summary: Nano-curcumin has a significant impact on cardiovascular risk factors in type 2 diabetic patients, reducing inflammation marker hs-CRP and lipoprotein levels, and potentially preventing atherosclerosis progression and cardiovascular events.

BIOFACTORS (2023)

添加到收藏夹

Article Endocrinology & Metabolism

The Effects of Nano-curcumin Supplementation on Leptin and Adiponectin in Migraine Patients: A Double-blind Clinical Trial Study from Gene Expression to Clinical Symptoms

Mohsen Sedighiyan et al.

Summary: The study suggests that nano-curcumin supplementation can significantly up-regulate adiponectin mRNA expression, increase its serum levels, and significantly reduce the frequency, severity, and duration of headaches. Nano-curcumin supplementation may be considered as a promising approach for migraine management and improvement of clinical symptoms.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2023)

添加到收藏夹

Article Oncology

Efficacy of curcumin for amelioration of radiotherapy-induced oral mucositis: a preliminary randomized controlled clinical trial

Vahid Ramezani et al.

Summary: This study evaluated the safety and efficacy of curcumin mouthwash and curcumin-nanocapsule in the treatment of radiation-induced oral mucositis (ROM). The results showed that both oral and topical application of curcumin could effectively reduce the symptoms and pain associated with ROM, with good safety profiles.

BMC CANCER (2023)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

Curcumin nanoparticles: the topical antimycotic suspension treating oral candidiasis

Souzy Kamal Anwar et al.

Summary: Nanocurcumin exhibits a good antifungal effect for the treatment of oral candidiasis as an alternative therapy to nystatin, although it takes longer time for therapeutic efficacy to appear.

ODONTOLOGY (2023)

添加到收藏夹

Article Pharmacology & Pharmacy

Evaluation of nano-curcumin against inhaled paraquat-induced lung injury in rats

Seyedeh Zahra Ghasemi et al.

Summary: This study aimed to evaluate the protective activity of nano-curcumin against paraquat-induced lung injury and found that nano-curcumin could ameliorate the lung damage. It also showed a synergistic effect between nano-curcumin and pioglitazone.

PHARMACOLOGICAL REPORTS (2023)

添加到收藏夹

Article Chemistry, Medicinal

Promising clinical outcomes of nano-curcumin treatment as an adjunct therapy in hospitalized COVID-19 patients: A randomized, double-blinded, placebo-controlled trial

Majid Sadeghizadeh et al.

Summary: Different immunomodulation strategies have been used to manage COVID-19 due to the complex immune-inflammatory processes involved in the pathogenesis of this infection. Curcumin, with its anti-inflammatory and antiviral properties, showed effectiveness as a complementary therapy in moderate-severe COVID-19 patients. The study found that nano-curcumin treatment significantly decreased inflammatory markers, improved chest CT scores, oxygen saturation levels, and reduced hospitalization duration.

PHYTOTHERAPY RESEARCH (2023)

添加到收藏夹

Review Cell & Tissue Engineering

Osteoporosis treatment using stem cell-derived exosomes: a systematic review and meta-analysis of preclinical studies

Xiaoyu He et al.

Summary: This study provides systematic evidence demonstrating the efficacy of stem cell-derived exosomes in improving bone loss in the treatment of osteoporosis. The results suggest that exosome treatment increases bone mass, improves bone microarchitecture, and enhances bone strength. This provides important evidence for the development of new treatment methods for osteoporosis.

STEM CELL RESEARCH & THERAPY (2023)

添加到收藏夹

Article Immunology

Mesenchymal stem cell-derived exosomes for treatment of sepsis

Kento Homma et al.

Summary: The pathogenesis of sepsis is an imbalance between pro-inflammatory and anti-inflammatory responses. MSC-derived extracellular vesicles (EVs) have shown beneficial effects for the treatment of acute lung injury (ALI) and sepsis. However, the present study demonstrated that EVs isolated from bone marrow-derived MSCs failed to attenuate the severity of multiorgan dysfunctions.

FRONTIERS IN IMMUNOLOGY (2023)

添加到收藏夹

Review Immunology

Extracellular vesicles as potential biomarkers and treatment options for liver failure: A systematic review up to March 2022

Wang Lu et al.

Summary: This systematic review analyzed the potential of extracellular vesicles (EVs) in liver failure and found that EVs can be used as biomarkers and treatment options for liver failure. Larger studies are needed to verify the diagnostic, predictive, and therapeutic value of EVs in liver failure.

FRONTIERS IN IMMUNOLOGY (2023)

添加到收藏夹

Article Food Science & Technology

Adjunctive nano-curcumin therapy improves inflammatory and clinical indices in children with cystic fibrosis: A randomized clinical trial

Saeedeh Talebi et al.

Summary: This prospective randomized clinical trial aimed to evaluate the effects of nano-curcumin as an anti-inflammatory agent and a CFTR modulator on clinical and inflammatory markers in children with CF. The results showed that nano-curcumin decreased the levels of high-sensitivity C-reactive protein and fecal calprotectin, and increased the level of interleukin-10. Moreover, it improved the overall quality of life and the subscale scores of the questionnaire.

FOOD SCIENCE & NUTRITION (2023)

添加到收藏夹

Article Chemistry, Inorganic & Nuclear

Chitosan based wound dressing patch loaded with curcumin tagged ZnO nanoparticles for potential wound healing application

R. Niranjan et al.

Summary: Researchers have developed a PVA/Chi/ZnO-Cur patch by incorporating nano-curcumin onto zinc oxide nanoparticles to enhance its antimicrobial and wound healing activities. Characterization using various techniques confirmed the properties of the patch. In vitro evaluations showed excellent biocompatibility, sustained drug release, and significant anti-bacterial activity. An in vivo study further confirmed the patch's wound healing properties.

INORGANIC CHEMISTRY COMMUNICATIONS (2023)

添加到收藏夹

Article Pharmacology & Pharmacy

Co-delivery of curcumin and PTTG1 siRNA by galactose receptor-targeted liposomes for enhanced anti-tumor effects in hepatocellular carcinoma

Minhee Kim et al.

Summary: This study examined the efficacy of combination therapy for hepatocellular carcinoma (HCC) using two types of hepatoma-targeting ligand-based liposomes to co-deliver curcumin and pituitary tumor modifying gene-1 (PTTG1) siRNA. The results showed that the combination treatment effectively inhibited tumor growth by suppressing the expression of Bcl-2 gene and increasing the expression of Caspase-3 gene in HCC. In the nude mouse model, intravenous injection of these liver-targeted liposome nano-pharmaceuticals effectively inhibited tumor growth. These results demonstrate the high potential of this combination therapy for HCC treatment.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2023)

添加到收藏夹

Article Biochemistry & Molecular Biology

Intranasal delivery of darunavir improves brain drug concentrations in mice for effective HIV treatment

Asit Kumar et al.

Summary: This study demonstrated that intranasal delivery of darunavir can enhance its penetration into the brain, bypassing the blood-brain barrier. Compared to intravenous administration, intranasal administration significantly increased darunavir concentration in the brain at both low and high doses, while reducing its concentration in plasma and liver.

BIOCHEMISTRY AND BIOPHYSICS REPORTS (2023)

添加到收藏夹

Article Chemistry, Medicinal

Nano-curcumin supplementation in patients with mild and moderate acute pancreatitis: A randomized, placebo-controlled trial

Maedeh Chegini et al.

Summary: This study investigated the effectiveness of nano-curcumin as an anti-inflammatory agent in patients with mild and moderate acute pancreatitis (AP). It was a double-blind, parallel-arm randomized controlled trial conducted in Tehran, Iran. The results showed that nano-curcumin supplementation reduced hospital length of stay, decreased the need for analgesics, and improved overall appetite in patients with AP. No adverse effects or mortality were reported. Further larger-scale multi-center trials are needed to confirm these findings.

PHYTOTHERAPY RESEARCH (2023)

添加到收藏夹

Article Materials Science, Ceramics

5-fluorouracil and curcuminoids extract from Curcuma longa L. loaded into nanohydroxyapatite as a drug delivery carrier for SKOV-3 and HepG2 cancer cells treatment

Thu Phuong Nguyen et al.

Ceramics International (2023)

添加到收藏夹

Article Biophysics

Polyphosphazene nanodrugs for targeting delivery and inflammation responsive release of curcumin to treat acute lung injury by effectively inhibiting cytokine storms

Xiaochen Su et al.

Summary: This study developed a highly cross-linked polyphosphazene nano-drug (PHCH) that enhances the water dispersion and antioxidant properties of curcumin (CUR), leading to improved treatment of acute lung injury (ALI). PHCH releases CUR in an inflammation environment and demonstrates substantial anti-inflammation activity. The smart polyphosphazene nano-drug shows potential for the clinical treatment of various inflammatory diseases, including ALI.

COLLOIDS AND SURFACES B-BIOINTERFACES (2023)

添加到收藏夹

Article Urology & Nephrology

The nano-micellar curcumin improves International Prostate Symptoms Score (IPSS) in patients with benign prostatic hyperplasia: a randomized clinical trial

Ali Akbar Karami et al.

Summary: This study aimed to assess the effectiveness of nano-micellar curcumin on biomedical indicators in patients with benign prostatic hyperplasia (BPH). The results showed that nano-micellar curcumin had a significant effect on IPSS, a low effect on high-sensitive C-reactive protein (hs-CRP), and a low to intermediate effect on malondialdehyde (MDA) level. The effect on other parameters was negligible.

WORLD JOURNAL OF UROLOGY (2023)

添加到收藏夹

Article Andrology

Effect of curcumin, and nano-curcumin on sperm function in varicocele rat model

Mohamad Reza Sadraei et al.

Summary: The study found that both curcumin and nano-curcumin as natural antioxidants had significant effects on spermatogenesis and sperm function in varicocelised rats, with nano-curcumin showing more effectiveness. This suggests that nano-curcumin may be a preferable option for treating infertility in individuals with varicocele.

ANDROLOGIA (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Does nano-curcumin supplementation improve hematological indices in critically ill patients with sepsis? A randomized controlled clinical trial

Fatemeh Naeini et al.

Summary: Nano-curcumin supplementation has a beneficial effect on hematological indices and inflammatory biomarkers in critically ill patients with sepsis, making it a potentially useful adjuvant therapy. However, more trials are needed to further explore the effects of nano-curcumin in the management of sepsis and its complications.

JOURNAL OF FOOD BIOCHEMISTRY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Neuroprotective effects of curcumin via autophagy induction in 6-hydrox-ydopamine Parkinson's models

Hai-Jun He et al.

Summary: The study shows that curcumin has neuroprotective effects in Parkinson's disease, both in vitro and in vivo. It inhibits cell apoptosis and induces autophagy through the AKT/mTOR signaling pathway. This leads to reduced accumulation of α-synuclein and improved parkinsonian disability scores.

NEUROCHEMISTRY INTERNATIONAL (2022)

添加到收藏夹

Article Chemistry, Medicinal

Curcumin suppress inflammatory response in traumatic brain injury via p38/MAPK signaling pathway

Guoqiang Li et al.

Summary: This study demonstrates the protective effect of curcumin on traumatic brain injury (TBI) and its molecular mechanisms involving the p38/MAPK signaling pathway. Curcumin ameliorates secondary brain injury and inflammation associated with TBI, indicating its potential as a therapeutic approach for TBI-related inflammation.

PHYTOTHERAPY RESEARCH (2022)

添加到收藏夹

Article Chemistry, Medicinal

Antiinflammatory potential of nano-curcumin as an alternative therapeutic agent for the treatment of mild-to-moderate hospitalized COVID-19 patients in a placebo-controlled clinical trial

Ali Asadirad et al.

Summary: This study found that nano-curcumin can be used as a complementary medication with anti-inflammatory effects to inhibit inflammatory complications and improve clinical manifestations and laboratory parameters in COVID-19 patients.

PHYTOTHERAPY RESEARCH (2022)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

COMPARATIVE EFFICACY OF 1% CURCUMIN NANOMICELLE GEL AND 2% CURCUMIN GEL FOR TREATMENT OF RECURRENT APHTHOUS STOMATITIS: A DOUBLE-BLIND RANDOMIZED CLINICAL TRIAL

Mahin Bakhshi et al.

Summary: This study demonstrates that 1% curcumin nanomicelle gel can effectively treat RAS, reducing pain and decreasing the size of lesions.

JOURNAL OF EVIDENCE-BASED DENTAL PRACTICE (2022)

添加到收藏夹

Review Pharmacology & Pharmacy

Evaluation of Recent Intranasal Drug Delivery Systems to the Central Nervous System

Tyler P. Crowe et al.

Summary: Neurological diseases are becoming increasingly prevalent and pose a significant burden on healthcare systems and societies. Intranasal administration, which bypasses the blood-brain barrier, shows promise in delivering potential therapies for these diseases. Optimizing this administration route can improve treatment safety and efficacy.

PHARMACEUTICS (2022)

添加到收藏夹

Article Chemistry, Medicinal

Targeted Drug Delivery to the Central Nervous System Using Extracellular Vesicles

Lina Zhou et al.

Summary: This article discusses the barrier of BBB to drug penetration and the use of EVs for targeted drug delivery to the CNS. Limited information on clinical trials is available, but studies on the peripheral nervous system may shed light on strategies for CNS drug delivery.

PHARMACEUTICALS (2022)

添加到收藏夹

Article Biology

The effects of nano-curcumin supplementation on adipokines levels in obese and overweight patients with migraine: a double blind clinical trial study

Mohsen Sedighiyan et al.

Summary: This study aimed to investigate the effects of nano-curcumin supplementation on adipokines levels and clinical signs in obese and overweight patients with migraine. The results showed that nano-curcumin can significantly reduce MCP-1 serum levels and also significantly reduce the attack frequencies, severity, and duration of headaches. These findings suggest that targeting curcumin may be a promising approach to migraine management.

BMC RESEARCH NOTES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dual Mechanism of Action of Curcumin in Experimental Models of Multiple Sclerosis

Ines ELBini-Dhouib et al.

Summary: The study found that curcumin has anti-inflammatory and antioxidant effects, which can alleviate the symptoms of multiple sclerosis and promote remyelination.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nano-Liposomes Double Loaded with Curcumin and Tetrandrine: Preparation, Characterization, Hepatotoxicity and Anti-Tumor Effects

Jia-Wen Song et al.

Summary: This study encapsulated curcumin and tetrandrine in nano-liposomes and added a stabilizer to improve their physicochemical properties and anti-tumor effects. The nano-liposomes showed high stability, solubility, and strong inhibitory effect on various cancer cells, with no significant toxicity observed in zebrafish.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Toward the Noninvasive Diagnosis of Alzheimer's Disease: Molecular Basis for the Specificity of Curcumin for Fibrillar Amyloid-β

Beenish Khurshid et al.

Summary: Recent studies have found that curcumin can be used for noninvasive optical imaging of retinal amyloid-beta plaques. Molecular dynamics simulations reveal that curcumin has specificity for different amyloid morphologies and its interaction is finely balanced with self-aggregation, which potentially increases the fluorescence signal.

ACS OMEGA (2022)

添加到收藏夹

Article Nutrition & Dietetics

Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial

Abbas Ali Sangouni et al.

Summary: This study investigated the effects of curcumin and/or coenzyme Q10 supplementation on the components of metabolic syndrome. The results showed that curcumin can improve dyslipidemia, but has no effect on body composition, hypertension, and glycemic control. Both coenzyme Q10 and the combination of curcumin and coenzyme Q10 showed no therapeutic effects in subjects with metabolic syndrome.

NUTRITION JOURNAL (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nano-curcumin supplementation in critically ill patients with sepsis: a randomized clinical trial investigating the inflammatory biomarkers, oxidative stress indices, endothelial function, clinical outcomes and nutritional status

Arash Karimi et al.

Summary: This study investigated the effects of nano-curcumin on patients with sepsis and found that it could improve inflammatory biomarkers, endothelial function, and oxidative stress indices, as well as reduce the duration of mechanical ventilation and disease progression. However, it did not show significant improvements in biochemical factors and nutritional status.

FOOD & FUNCTION (2022)

添加到收藏夹

Article Neurosciences

The synergistic effects of nano-curcumin and coenzyme Q10 supplementation in migraine prophylaxis: a randomized, placebo-controlled, double-blind trial

Mohammad Parohan et al.

Summary: The combined supplementation of nano-curcumin and CoQ10 showed significant improvement in migraine symptoms and quality of life, with no reported side effects.

NUTRITIONAL NEUROSCIENCE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano-Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial

Niyaz M. Honarvar et al.

Summary: The combination of n-3 fatty acids and nano-curcumin significantly reduced migraine attack frequency and serum IL-1 beta levels, suggesting a potential therapeutic effect for migraine management. Further studies are needed to confirm these findings.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2021)

添加到收藏夹

Article Biology

The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial

Mina Abdolahi et al.

Summary: The study found that both omega-3 fatty acids (W-3 FAs) and the combination of W-3 and nanocurcumin can reduce serum levels and gene expression of VCAM in patients with episodic migraine. Nanocurcumin supplementation alone and the control group did not show significant changes.

BMC RESEARCH NOTES (2021)

添加到收藏夹

Article Cell Biology

Using gelatin/curcumin nano-fiber membranes as scaffolds in a subcutaneous model for tissue engineered cartilages

Bo Kyoung Kang et al.

Summary: This study explored the feasibility of using gelatin/curcumin nano-fiber membranes as scaffolds to construct engineered cartilage tissues. The results showed that curcumin had no significant effect on chondrocyte growth, but the experimental group exhibited thicker and more homogeneous cartilage matrix compared to the control group. Overall, gelatin/curcumin scaffolds hold great clinical potential in the construction of engineered cartilage tissues.

CELL AND TISSUE BANKING (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Nanoparticles for Targeted Brain Drug Delivery: What Do We Know?

Ruben G. R. Pinheiro et al.

Summary: Nanomedicine has the potential to treat neurological diseases by modifying nanoparticles to cross the blood-brain barrier and target the brain tissue directly.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

添加到收藏夹

Review Nanoscience & Nanotechnology

Potential of Nanocarrier-Based Drug Delivery Systems for Brain Targeting: A Current Review of Literature

Badriyah Shadid Alotaibi et al.

Summary: The emergence of nanotechnologies, such as nanocarriers and nanotherapeutics, has revolutionized treatment strategies with more efficacious drug delivery systems, particularly for targeting brain diseases. Various nanocarrier-based composites have been developed for drug targeting towards brain cells, with ongoing advancements in technologies and research in this area.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2021)

添加到收藏夹

Article Endocrinology & Metabolism

Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective An- gioplasty; A Randomized Clinical Trial

Bijan Helli et al.

Summary: This study found that both curcumin and nano-curcumin have significant effects on improving lipid profiles, oxidative stress, and inflammatory factors related to heart in patients. Nano-curcumin showed better efficacy than curcumin in certain indicators.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2021)

添加到收藏夹

Article Oncology

Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling

L. Gao et al.

Summary: Curcumin can inhibit the proliferation and induce apoptosis of gemcitabine-resistant non-small cell lung cancer by upregulating the expression of lncRNA-MEG3 and PTEN. This study provides evidence for the potential clinical application of curcumin in the treatment of gemcitabine-resistant non-small cell lung cancer.

CLINICAL & TRANSLATIONAL ONCOLOGY (2021)

添加到收藏夹

Article Neurosciences

Neuroprotective effects of curcumin-loaded nanophytosome on ketamine-induced schizophrenia-like behaviors and oxidative damage in male mice

Akbar Hajizadeh Moghaddam et al.

Summary: The study demonstrated that developing curcumin-loaded nanophytosome can enhance the bioavailability of curcumin, resulting in stronger neuroprotective effects against ketamine-induced schizophrenia-like behaviors and oxidative damages.

NEUROSCIENCE LETTERS (2021)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Strategies for delivering therapeutics across the blood-brain barrier

Georg C. Terstappen et al.

Summary: The blood-brain barrier presents a challenge for delivering therapeutics to the central nervous system, particularly for biopharmaceuticals. Non-invasive approaches have been developed to help overcome this challenge, with increasing research efforts focusing on technologies to deliver therapeutics to the CNS, some of which have entered clinical testing. Developing effective strategies for crossing the blood-brain barrier is crucial for treating CNS disorders, with a particular emphasis on non-invasive methods such as receptor-mediated transcytosis and the use of neurotropic viruses, nanoparticles, and exosomes.

NATURE REVIEWS DRUG DISCOVERY (2021)

添加到收藏夹

Review Nutrition & Dietetics

Potential Therapeutic Effects of Curcumin on Glycemic and Lipid Profile in Uncomplicated Type 2 Diabetes-A Meta-Analysis of Randomized Controlled Trial

Emma Altobelli et al.

Summary: The study demonstrated that curcumin has a positive impact on glycemic and lipid profiles in subjects with uncomplicated type 2 diabetes, showing significant reductions in glycosylated hemoglobin, HOMA, and LDL. However, further research is needed to test the efficacy and safety of curcumin in this population.

NUTRIENTS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Enhanced anticancer activities of curcumin-loaded green gum acacia-based silver nanoparticles against melanoma and breast cancer cells

Imran Ali et al.

Summary: The green-synthesized silver nanoparticles as nano-carriers effectively increased the loading capacity of curcumin, demonstrating good anticancer activities against various cancer cell lines.

APPLIED NANOSCIENCE (2021)

添加到收藏夹

Article Chemistry, Medicinal

The effects of nano-curcumin supplementation on glycemic control, blood pressure, lipid profile, and insulin resistance in patients with the metabolic syndrome: A randomized, double-blind clinical trial

Zohre Bateni et al.

Summary: This study demonstrated that supplementation with nano-micelle curcumin significantly reduced serum triglyceride levels and HOMA-beta in MetS patients. However, there were no significant differences in other anthropometric measurements, blood pressure, and lipid profile variables at the end of the study.

PHYTOTHERAPY RESEARCH (2021)

添加到收藏夹

Review Chemistry, Medicinal

The Immunomodulatory and Anti-Inflammatory Effect of Curcumin on Immune Cell Populations, Cytokines, and In Vivo Models of Rheumatoid Arthritis

Sebastian Makuch et al.

Summary: Rheumatoid arthritis is a chronic autoimmune disorder that affects joints, leading to irreversible tissue degeneration and inflammation. Curcumin, a natural compound with anti-inflammatory properties, shows potential in modulating inflammatory responses and could play a role in the treatment of rheumatoid arthritis.

PHARMACEUTICALS (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Curcumin Loading on Alginate Nano-Micelle for Anti-Infection and Colonic Wound Healing

Zhiyong Zhang et al.

Summary: The study demonstrated that C-A-NM has a positive impact on wound healing in the colon, with significant effects in promoting collagen induction and reducing bacterial activity.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Novel concept of exosome-like liposomes for the treatment of Alzheimer's disease

Mario Fernandes et al.

Summary: Exosomes-like liposomes were developed for controlled delivery, efficiently encapsulating curcumin and showing potential neuroprotection without toxicity. These innovative carriers are stable, protect the cargo, and are uptaken by neuronal cells, offering a positive alternative strategy for Alzheimer's disease therapy.

JOURNAL OF CONTROLLED RELEASE (2021)

添加到收藏夹

Review Chemistry, Medicinal

Effects of the Use of Curcumin on Ulcerative Colitis and Crohn's Disease: A Systematic Review

Ricardo de Alvares Goulart et al.

Summary: Curcuma longa derivatives have been considered as adjuvants in the therapeutic approach of patients with inflammatory bowel disease (IBD). Clinical trials and meta-analyses have shown promising results in using curcumin in patients with Crohn's disease (CD) and ulcerative colitis (UC), but there are also controversial findings.

JOURNAL OF MEDICINAL FOOD (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Recent advances on drug development and emerging therapeutic agents for Alzheimer's disease

Teeba Athar et al.

Summary: Alzheimer's disease is a complex, multifactorial, and progressive neurodegenerative disease with currently limited treatment options. Despite global efforts to identify new therapeutic agents, only one drug has been approved by the FDA for the treatment of AD since 2003. Further research is needed to develop novel therapeutic strategies to combat this century-old disease.

MOLECULAR BIOLOGY REPORTS (2021)

添加到收藏夹

Article Chemistry, Medicinal

A triple-blind, placebo-controlled, randomized clinical trial to evaluate the effect of curcumin-containing nanomicelles on cellular immune responses subtypes and clinical outcome in COVID-19 patients

Mehdi Hassaniazad et al.

Summary: This study showed that nano-curcumin may accelerate recovery of the acute inflammatory phase in COVID-19 patients by modulating inflammatory immune responses, indicating its potential effectiveness in controlling inflammatory responses in inflammatory diseases, including COVID-19.

PHYTOTHERAPY RESEARCH (2021)

添加到收藏夹

Review Geriatrics & Gerontology

Extracellular Vesicles for the Diagnosis and Treatment of Parkinson's Disease

Raghavendra Upadhya et al.

Summary: Extracellular vesicles shed by neurons and glia play crucial roles in neurodegenerative diseases, transferring pathological miRNAs and proteins while also serving as carriers for therapeutic drugs. They hold promise for both treatment and biomarker discovery in neurodegenerative diseases.

AGING AND DISEASE (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

The blood-brain barrier: Physiology and strategies for drug delivery

Rucha Pandit et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

添加到收藏夹

Review Food Science & Technology

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

Sita Sharan Patel et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Synthesis of Silver Nanoparticles Using Curcumin-Cyclodextrins Loaded into Bacterial Cellulose-Based Hydrogels for Wound Dressing Applications

Abhishek Gupta et al.

BIOMACROMOLECULES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nonwoven fabric supported, chitosan membrane anchored with curcumin/TiO2 complex: Scaffolds for MRSA infected wound skin reconstruction

Roopesh Marulasiddeshwara et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Clinical Neurology

The global burden of neurological disorders: translating evidence into policy

Valery L. Feigin et al.

LANCET NEUROLOGY (2020)

添加到收藏夹

Article Materials Science, Multidisciplinary

Overcoming blood-brain barrier transport: Advances in nanoparticle-based drug delivery strategies

Shichao Ding et al.

MATERIALS TODAY (2020)

添加到收藏夹

Article Oncology

Antimicrobial photodynamic and wound healing activity of curcumin encapsulated in silica nanoparticles

Mahtab Mirzahosseinipour et al.

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)

添加到收藏夹

Article Chemistry, Medicinal

Beneficial effects of nano-curcumin supplement on depression and anxiety in diabetic patients with peripheral neuropathy: A randomized, double-blind, placebo-controlled clinical trial

Sara Asadi et al.

PHYTOTHERAPY RESEARCH (2020)

添加到收藏夹

Review Chemistry, Medicinal

Molecular mechanism of curcumin action in signaling pathways: Review of the latest research

Przemyslaw Liczbinski et al.

PHYTOTHERAPY RESEARCH (2020)

添加到收藏夹

Article Engineering, Biomedical

Neuronal mitochondria-targeted delivery of curcumin by biomimetic engineered nanosystems in Alzheimer's disease mice

Chunhong Gao et al.

ACTA BIOMATERIALIA (2020)

添加到收藏夹

Article Endocrinology & Metabolism

Aerobic exercise and nano-curcumin supplementation improve inflammation in elderly females with metabolic syndrome

Ali Osali

DIABETOLOGY & METABOLIC SYNDROME (2020)

添加到收藏夹

Article Neurosciences

Protein Aggregation and Dysfunction of Autophagy-Lysosomal Pathway: A Vicious Cycle in Lysosomal Storage Diseases

Antonio Monaco et al.

FRONTIERS IN MOLECULAR NEUROSCIENCE (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Nanocurcumin: A Promising Candidate for Therapeutic Applications

Adhimoolam Karthikeyan et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

HSA-curcumin nanoparticles: a promising substitution for Curcumin as a Cancer chemoprevention and therapy

Zahra Matloubi et al.

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

添加到收藏夹

Article Clinical Neurology

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia A Randomized Clinical Trial

Suzanne Craft et al.

JAMA NEUROLOGY (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

AmyloLipid Nanovesicles: A self-assembled lipid-modified starch hybrid system constructed for direct nose-to-brain delivery of curcumin

Amnon C. Sintov

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

An EGF- and Curcumin-Co-Encapsulated Nanostructured Lipid Carrier Accelerates Chronic-Wound Healing in Diabetic Rats

Hye-Jin Lee et al.

MOLECULES (2020)

添加到收藏夹

Letter Medicine, Research & Experimental

The clinical effect of Nano micelles containing curcumin as a therapeutic supplement in patients with COVID-19 and the immune responses balance changes following treatment: A structured summary of a study protocol for a randomised controlled trial

Mehdi Hassaniazad et al.

TRIALS (2020)

添加到收藏夹

Review Pharmacology & Pharmacy

Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications

Javad Sharifi-Rad et al.

FRONTIERS IN PHARMACOLOGY (2020)

添加到收藏夹

Article Immunology

Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients

Hamed Valizadeh et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Curcumin-laden exosomes target ischemic brain tissue and alleviate cerebral ischemia-reperfusion injury by inhibiting ROS-mediated mitochondrial apoptosis

Ruyi He et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

添加到收藏夹

Review Nutrition & Dietetics

The Potential Role of Nutraceuticals as an Adjuvant in Breast Cancer Patients to Prevent Hair Loss Induced by Endocrine Therapy

Giorgio Dell'Acqua et al.

NUTRIENTS (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Targeted exosome coating gene-chem nanocomplex as nanoscavenger for clearing α-synuclein and immune activation of Parkinson's disease

Linying Liu et al.

SCIENCE ADVANCES (2020)

添加到收藏夹

Article Integrative & Complementary Medicine

The effects of nano-curcumin supplementation on Th1/Th17 balance in migraine patients: A randomized controlled clinical trial

Mona Djalali et al.

COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE (2020)

添加到收藏夹

Article Integrative & Complementary Medicine

Comparison of oral Nano-Curcumin with oral prednisolone on oral lichen planus: a randomized double-blinded clinical trial

Seyed Javad Kia et al.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2020)

添加到收藏夹

Article Rheumatology

The Effect of Nanocurcumin in Improvement of Knee Osteoarthritis: A Randomized Clinical Trial

Kamila Hashemzadeh et al.

CURRENT RHEUMATOLOGY REVIEWS (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Facile design of autogenous stimuli-responsive chitosan/hyaluronic acid nanoparticles for efficient small molecules to protein delivery

Parinaz Sabourian et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Article Immunology

Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress

Wen-yuan Zhang et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin and/or omega-3 polyunsaturated fatty acids supplementation reduces insulin resistance and blood lipids in individuals with high risk of type 2 diabetes: a randomised controlled trial

Rohith N. Thota et al.

LIPIDS IN HEALTH AND DISEASE (2019)

添加到收藏夹

Article Nutrition & Dietetics

Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with nonalcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial

Seyed Ali Jazayeri-Tehrani et al.

NUTRITION & METABOLISM (2019)

添加到收藏夹

Article Endocrinology & Metabolism

The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms

Mina Abdolahi et al.

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS (2019)

添加到收藏夹

Article Multidisciplinary Sciences

pH-responsive and targeted delivery of curcumin via phenylboronic acid-functionalized ZnO nanoparticles for breast cancer therapy

Mousumi Kundu et al.

JOURNAL OF ADVANCED RESEARCH (2019)

添加到收藏夹

Article Integrative & Complementary Medicine

Nano curcumin supplementation reduced the severity of diabetic sensorimotor polyneuropathy in patients with type 2 diabetes mellitus: A randomized double-blind placebo- controlled clinical trial

Sara Asadi et al.

COMPLEMENTARY THERAPIES IN MEDICINE (2019)

添加到收藏夹

Article Clinical Neurology

Safety and efficacy of midazolam nasal spray in the outpatient treatment of patients with seizure clusters-a randomized, double-blind, placebo-controlled trial

Kamil Detyniecki et al.

EPILEPSIA (2019)

添加到收藏夹

Article Nutrition & Dietetics

Low-Dose Curcumin Nanoparticles Normalise Blood Pressure in Male Wistar Rats with Diet-Induced Metabolic Syndrome

Ryan du Preez et al.

NUTRIENTS (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects

Raghavendhar R. Kotha et al.

MOLECULES (2019)

添加到收藏夹

Article Neurosciences

Neuroprotective effects of curcumin lipid-core nanocapsules in a model Alzheimer's disease induced by β-amyloid 1-42 peptide in aged female mice

Renata Giacomeli et al.

BRAIN RESEARCH (2019)

添加到收藏夹

Article Biophysics

Enhanced wound healing by PVA/Chitosan/Curcumin patches: In vitro and in vivo study

R. Niranjan et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

添加到收藏夹

Article Oncology

Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer

Lihua Wang et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

A novel synthesis of selenium nanoparticles encapsulated PLGA nanospheres with curcumin molecules for the inhibition of amyloid beta aggregation in Alzheimer's disease

Xinlong Huo et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2019)

添加到收藏夹

Review Physiology

BLOOD-BRAIN BARRIER: FROM PHYSIOLOGY TO DISEASE AND BACK

Melanie D. Sweeney et al.

PHYSIOLOGICAL REVIEWS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells

Jiawei Zhang et al.

MOLECULAR IMMUNOLOGY (2019)

添加到收藏夹

Article Acoustics

Ultrasound Microbubbles Enhance the Activity of Vancomycin Against Staphylococcus epidermidis Biofilms In Vivo

Ying Dong et al.

JOURNAL OF ULTRASOUND IN MEDICINE (2018)

添加到收藏夹

Article Immunology

Curcumin affords neuroprotection and inhibits α-synuclein aggregation in lipopolysaccharide-induced Parkinson's disease model

Neha Sharma et al.

INFLAMMOPHARMACOLOGY (2018)

添加到收藏夹

Article Engineering, Biomedical

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

Tian Tian et al.

BIOMATERIALS (2018)

添加到收藏夹

Article Neurosciences

A Novel Combination of ω-3 Fatty Acids and Nano-Curcumin Modulates Interleukin-6 Gene Expression and High Sensitivity C-reactive Protein Serum Levels in Patients with Migraine: A Randomized Clinical Trial Study

Mina Abdolahi et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2018)

添加到收藏夹

Article Cell Biology

Phytosomal curcumin inhibits tumor growth in colitis-associated colorectal cancer

Reyhaneh Moradi Marjaneh et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Curcumin targets multiple enzymes involved in the ROS metabolic pathway to suppress tumor cell growth

Yonika Arum Larasati et al.

SCIENTIFIC REPORTS (2018)

添加到收藏夹

Article Medicine, Research & Experimental

Localized delivery of curcumin into brain with polysorbate 80-modified cerasomes by ultrasound-targeted microbubble destruction for improved Parkinson's disease therapy

Nisi Zhang et al.

THERANOSTICS (2018)

添加到收藏夹

Article Pharmacology & Pharmacy

Polymeric Nano-Encapsulation of Curcumin Enhances its Anti-Cancer Activity in Breast (MDA-MB231) and Lung (A549) Cancer Cells Through Reduction in Expression of HIF-1 alpha and Nuclear p65 (Rel A)

Mohammed N. Khan et al.

CURRENT DRUG DELIVERY (2018)

添加到收藏夹

Article Cell Biology

Curcumin Attenuates gp120-Induced Microglial Inflammation by Inhibiting Autophagy via the PI3K Pathway

Guiling Chen et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery

Niyanta N. Kumar et al.

JOURNAL OF CONTROLLED RELEASE (2018)

添加到收藏夹

Article Instruments & Instrumentation

Curcumin-loaded self-nanomicellizing solid dispersion system: part II: in vivo safety and efficacy assessment against behavior deficit in Alzheimer disease

Ankit Parikh et al.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH (2018)

添加到收藏夹

Article Nanoscience & Nanotechnology

Curcumin-loaded chitosan-bovine serum albumin nanoparticles potentially enhanced A β 42 phagocytosis and modulated macrophage polarization in Alzheimer's disease

Rui Yang et al.

NANOSCALE RESEARCH LETTERS (2018)

添加到收藏夹

Review Integrative & Complementary Medicine

Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers

Rohitash Jamwal

JOURNAL OF INTEGRATIVE MEDICINE-JIM (2018)

添加到收藏夹

Review Oncology

Nutraceuticals in prostate cancer therapeutic strategies and their neo-adjuvant use in diverse populations

Dominique Reed et al.

NPJ PRECISION ONCOLOGY (2018)

添加到收藏夹

Article Neurosciences

Enhanced Therapeutic Potential of Nano-Curcumin Against Subarachnoid Hemorrhage-Induced Blood-Brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress

Zong-yong Zhang et al.

MOLECULAR NEUROBIOLOGY (2017)

添加到收藏夹

Article Genetics & Heredity

The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients

Mina Abdolahi et al.

IMMUNOGENETICS (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Nano cellulose dispersed chitosan film with Ag NPs/Curcumin: An in vivo study on Albino Rats for wound dressing

S. K. Bajpai et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel

Lin Sun et al.

JOURNAL OF CONTROLLED RELEASE (2017)

添加到收藏夹

Article Chemistry, Medicinal

A Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group Study

Augustine Amalraj et al.

JOURNAL OF MEDICINAL FOOD (2017)

添加到收藏夹

Article Materials Science, Biomaterials

Effects of curcumin-loaded PLGA nanoparticles on the RG2 rat glioma model

Merdan Orunoglu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

添加到收藏夹

Article Biotechnology & Applied Microbiology

Nanoformulated natural therapeutics for management of streptozotocin-induced diabetes: potential use of curcumin nanoformulation

Yousra M. El-Far et al.

NANOMEDICINE (2017)

添加到收藏夹

Article Materials Science, Multidisciplinary

Nano-formulated curcumin accelerates acute wound healing through Dkk-1-mediated fibroblast mobilization and MCP-1-mediated anti-inflammation

Xinyi Dai et al.

NPG ASIA MATERIALS (2017)

添加到收藏夹

Article Multidisciplinary Sciences

Nanocurcumin is superior to native curcumin in preventing degenerative changes in Experimental Cerebral Malaria

Chaitanya Dende et al.

SCIENTIFIC REPORTS (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Antiplasmodial Activity and Toxicological Assessment of Curcumin PLGA-Encapsulated Nanoparticles

Zulaikha A. Busari et al.

FRONTIERS IN PHARMACOLOGY (2017)

添加到收藏夹

Article Neurosciences

The Combined Effects of ω-3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients

Neda Soveyd et al.

CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2017)

添加到收藏夹

Review Medicine, Research & Experimental

Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies

Hamed Mirzaei et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Docosahexaenoic acid-mediated, targeted and sustained brain delivery of curcumin microemulsion

Rajshree L. Shinde et al.

DRUG DELIVERY (2017)

添加到收藏夹

Article Neurosciences

Effects of nanoparticle-encapsulated curcumin on HIV-gp120-associated neuropathic pain induced by the P2X3 receptor in dorsal root ganglia

Shanhong Zhao et al.

BRAIN RESEARCH BULLETIN (2017)

添加到收藏夹

Article Pharmacology & Pharmacy

Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus

Raghu Ganugula et al.

BRITISH JOURNAL OF PHARMACOLOGY (2017)

添加到收藏夹

Article Medicine, Research & Experimental

Anti-oxidative effects of curcumin on immobilization-induced oxidative stress in rat brain, liver and kidney

Saeed Samarghandian et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Delivery of Dual Drug Loaded Lipid Based Nanoparticles across the Blood-Brain Barrier Impart Enhanced Neuroprotection in a Rotenone Induced Mouse Model of Parkinson's Disease

Paromita Kundu et al.

ACS CHEMICAL NEUROSCIENCE (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Neuroprotective effect of curcumin-loaded lactoferrin nano particles against rotenone induced neurotoxicity

V. Satish Bollimpelli et al.

NEUROCHEMISTRY INTERNATIONAL (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Curcumin Nanoformulation for Cervical Cancer Treatment

Mohd S. Zaman et al.

SCIENTIFIC REPORTS (2016)

添加到收藏夹

Article Multidisciplinary Sciences

Curcumin inhibits HIV-1 by promoting Tat protein degradation

Amjad Ali et al.

SCIENTIFIC REPORTS (2016)

添加到收藏夹

Review Chemistry, Medicinal

Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives

Vanessa Lopes-Rodrigues et al.

PHARMACEUTICALS (2016)

添加到收藏夹

Article Neurosciences

Curcumin, encapsulated in nano-sized PLGA, down-regulates nuclear factor κB (p65) and subarachnoid hemorrhage induced early brain injury in a rat model

Chih-Zen Chang et al.

BRAIN RESEARCH (2015)

添加到收藏夹

Article Nanoscience & Nanotechnology

Curcumin-encapsulated nanoparticles as innovative antimicrobial and wound healing agent

Aimee E. Krausz et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin Increases HSP70 Expression in Primary Rat Cortical Neuronal Apoptosis Induced by gp120 V3 Loop Peptide

Chenglai Xia et al.

NEUROCHEMICAL RESEARCH (2015)

添加到收藏夹

Article Pharmacology & Pharmacy

Curcumin Inhibits the AKT/NF-κB Signaling via CpG Demethylation of the Promoter and Restoration of NEP in the N2a Cell Line

Yushuang Deng et al.

AAPS JOURNAL (2014)

添加到收藏夹

Article Pharmacology & Pharmacy

Development and optimization of curcumin-loaded mannosylated chitosan nanoparticles using response surface methodology in the treatment of visceral leishmaniasis

Pramila Chaubey et al.

EXPERT OPINION ON DRUG DELIVERY (2014)

添加到收藏夹

Review Chemistry, Multidisciplinary

Quantitative analysis of drug delivery to the brain via nasal route

Luba Kozlovskaya et al.

JOURNAL OF CONTROLLED RELEASE (2014)

添加到收藏夹

Article Medicine, Research & Experimental

Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia

A. Kalani et al.

LIFE SCIENCES (2014)

添加到收藏夹

Review Biochemistry & Molecular Biology

The Chemistry of Curcumin: From Extraction to Therapeutic Agent

Kavirayani Indira Priyadarsini

MOLECULES (2014)

添加到收藏夹

Article Pharmacology & Pharmacy

Enhanced brain targeting of curcumin by intranasal administration of a thermosensitive poloxamer hydrogel

Xi Chen et al.

JOURNAL OF PHARMACY AND PHARMACOLOGY (2013)

添加到收藏夹

Article Pharmacology & Pharmacy

Innovative Preparation of Curcumin for Improved Oral Bioavailability

Hiroki Sasaki et al.

BIOLOGICAL & PHARMACEUTICAL BULLETIN (2011)

添加到收藏夹

Review Oncology

Advanced Drug Delivery Systems of Curcumin for Cancer Chemoprevention

Shyam S. Bansal et al.

CANCER PREVENTION RESEARCH (2011)

添加到收藏夹

Article Neurosciences

Neuroprotective and Neurorescue Effects of a Novel Polymeric Nanoparticle Formulation of Curcumin (NanoCurc (TM)) in the Neuronal Cell Culture and Animal Model: Implications for Alzheimer's Disease

Balmiki Ray et al.

JOURNAL OF ALZHEIMERS DISEASE (2011)

添加到收藏夹

Article Biochemistry & Molecular Biology

Curcumin Modulates Nuclear Factor κB (NF-κB)-mediated Inflammation in Human Tenocytes in Vitro ROLE OF THE PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY

Constanze Buhrmann et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

添加到收藏夹

Article Pharmacology & Pharmacy

Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer

J. Shaikh et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2009)

添加到收藏夹

Review Medicine, Research & Experimental

Bioavailability of curcumin: Problems and promises

Preetha Anand et al.

MOLECULAR PHARMACEUTICS (2007)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.