期刊
CLINICAL NUTRITION
卷 42, 期 12, 页码 2540-2545出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.clnu.2023.10.014
关键词
Lactose; Malabsorption; Sarcopenia; Intolerance; Older
Lactose malabsorption is a common condition caused by intestinal lactase deficiency, but it doesn't always result in gastrointestinal symptoms. Excluding milk and dairy products from the diet may lead to nutritional disadvantages, especially for older adults. Milk and dairy products are important sources of nutrients that can impact bone and muscle health. Additionally, dairy intake has been associated with prevention of chronic diseases and overall mortality.
Lactose malabsorption is a very common condition due to intestinal lactase deficiency. Post weaning, a genetically programmed and irreversible reduction of lactase activity occurs in the majority of the world's population. Lactose malabsorption does not necessarily result in gastrointestinal symptoms, i.e. lactose intolerance, which occurs in approximately one third of those with lactase deficiency. In the absence of well-established guidelines, the common therapeutic approach tends to exclude milk and dairy products from the diet.However, this strategy may have serious nutritional disadvantages. Mainly in particular categories, such as the older adults, the approach to lactose malabsorption may deserve careful considerations. Milk and dairy products are an important supply of a wide range of nutrients that contribute to meet the nutritional needs in different life stages. Dietary composition can significantly impact the mechanisms leading to age-related loss of bone mineral density, skeletal muscle mass or function and overall risk of sarcopenia. Moreover, in the latest years, different lines of evidence have highlighted an association between dairy intake and prevention of chronic diseases as well as all-cause mortality.The aim of this opinion paper is to provide an overview of lactose malabsorption and intolerance in the older adults and their implications in clinical practice.(c) 2023 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
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