☆ 4.6 Article

Theoretical Investigations on the Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes: Mechanism Insights and Regioselectivity Origins

ACS OMEGA (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Organic

Rh(III)-Catalyzed Oxidative C-H Activation/Annulation of Salicylaldehydes with Masked Enynes for the Synthesis of Chromones

Bo Li et al.

Summary: A rhodium(III)-catalyzed oxidative C-H activation/annulation of salicylaldehydes with propargylic acetates was developed for the regioselective synthesis of 3-vinyl chromones in good yields with broad functional group tolerance. 3-Vinyl chromones were converted into biologically active benzo[c]xanthone by I2-mediated oxidative electrocyclization.

JOURNAL OF ORGANIC CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Organic

Ru(II)-Catalyzed Decarbonylative Alkylation and Annulations of Benzaldehydes with Iodonium Ylides under Chelation Assistance

Xiang Li et al.

Summary: A Ru(II)-catalyzed synthesis method has been developed for the efficient formation of dibenzo[b,d]furans and NH-free carbazolones. The reaction shows mild conditions, low catalyst loading, and broad substrate compatibility. Hydroxy and free amino groups were found to be effective directing groups.

ORGANIC LETTERS (2022)

添加到收藏夹

Article Chemistry, Organic

Metal-Free One-Pot Annulative Coupling of 2-Hydroxybenzaldehydes with β-Ketothioamides: Access to Diverse 2-Arylimino-2H-Chromenes

Pragya Pali et al.

Summary: A concise and practical method has been developed to synthesize 2-arylimino-2H-chromene through a two-component cascade reaction, providing diverse chromene scaffolds and enriching the research field of beta-ketothioamides. The method is characterized by metal- and additive-free conditions, mild base, exclusive regioselectivity, high efficiency, and nonhazardous reagents.

JOURNAL OF ORGANIC CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

CpIr(iii) and CpRh(iii)-catalyzed annulation of salicylaldehydes with fluorinated vinyl tosylates

Shuwen Zhao et al.

Summary: A mild, selective, and redox-neutral C-H activation/annulation reaction of salicylaldehydes with fluorovinyl tosylates is reported. The use of monofluorovinyl tosylate leads to the synthesis of C2- and C3-substitution-free chromones, while difluorovinyl tosylate results in the construction of C2-fluoroalkoxy chromones. The reaction exhibits mild conditions and good functional-group tolerance.

CHEMICAL COMMUNICATIONS (2022)

添加到收藏夹

Review Chemistry, Organic

Synthesis and Reactivity of Electron-Deficient 3-Vinylchromones

Vyacheslav Y. Sosnovskikh

Summary: This review summarizes the methods and data for synthesizing electron-deficient 3-vinylchromones with electron-withdrawing groups, focusing on their reactivity and chemical properties. These compounds are obtained mainly through Knoevenagel condensation, Wittig reaction, and palladium-catalyzed cross-couplings, and exhibit high reactivity in reactions with mono- and dinucleophiles, ambiphilic cyclizations, and cycloaddition reactions. They serve as valuable building blocks for complex heterocyclic systems and their chemical transformations usually involve attacks at the C-2 atom, ring opening, and recyclization.

SYNOPEN (2021)

添加到收藏夹

Article Chemistry, Applied

Regioselective Access to 3-Ethylideneflavanones via Rhodium(I)-Catalyzed 1,3-Enyne Hydroacylation/Annulation Cascades

Zhi-Xin Chang et al.

Summary: The highly efficient synthesis of 3-ethylideneflavanones through sequential rhodium(I)-catalyzed hydroacylation of terminal aryl-substituted 1,3-enynes with chelating aldehydes and annulation is described. This method highlights unprecedented C3-regioselective hydroacylation of 1,3-enynes, excellent functional group compatibility, and complete atom economy.

ADVANCED SYNTHESIS & CATALYSIS (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors

Yan-Fa Yu et al.

ACS CHEMICAL NEUROSCIENCE (2020)

添加到收藏夹

Article Chemistry, Organic

Design and Synthesis of Novel Nonsteroidal Phytoestrogen-based Probes as Potential Biomarker: Evaluation of Anticancer Activity and Docking Studies

Sumit Kumar et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY (2017)

添加到收藏夹

Article Chemistry, Medicinal

Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances

Joana Reis et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

添加到收藏夹

Review Chemistry, Multidisciplinary

Analyzing Reaction Rates with the Distortion/Interaction-Activation Strain Model

F. Matthias Bickelhaupt et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

添加到收藏夹

Article Chemistry, Organic

One-Pot Synthesis of Benzopyran-4-ones with Cancer Preventive and Therapeutic Potential

Oualid Talhi et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Organic

Synthesis of 2,5-epoxy-1,4-benzoxazepines via rhodium(II)-catalyzed reaction of 1-tosyl-1,2,3-triazoles and salicylaldehydes

Jiang Meng et al.

TETRAHEDRON (2016)

添加到收藏夹

Review Chemistry, Multidisciplinary

Chromone: A Valid Scaffold in Medicinal Chemistry

Alexandra Gaspar et al.

CHEMICAL REVIEWS (2014)

添加到收藏夹

Article Chemistry, Multidisciplinary

Effect of the Damping Function in Dispersion Corrected Density Functional Theory

Stefan Grimme et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)

添加到收藏夹

Article Chemistry, Physical

A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu

Stefan Grimme et al.

JOURNAL OF CHEMICAL PHYSICS (2010)

添加到收藏夹

Review Chemistry, Physical

Benchmark Energetic Data in a Model System for Grubbs II Metathesis Catalysis and Their Use for the Development, Assessment, and Validation of Electronic Structure Methods

Yan Zhao et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)

添加到收藏夹

Review Chemistry, Physical

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

Aleksandr V. Marenich et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2009)

添加到收藏夹

Review Chemistry, Multidisciplinary

Density functionals with broad applicability in chemistry

Yan Zhao et al.

ACCOUNTS OF CHEMICAL RESEARCH (2008)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.