☆ 4.8 Article

Ultrasound-amplified polymetallic nanozyme-induced pyroptosis for lung cancer theranostics

NANO TODAY (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Multidisciplinary Sciences

Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme

Wenhui Gao et al.

Summary: We report a carbon dot (C-dot) superoxide dismutase (SOD) nanozyme with a catalytic activity comparable to that of natural enzymes. The SOD-like activity of C-dot nanozyme relies on specific chemical modifications and conjugated carbonyl groups for binding and electron transfer. Furthermore, the C-dot SOD nanozymes exhibit intrinsic targeting ability to oxidation-damaged cells and effectively protect neuron cells in the ischemic stroke mouse model.

NATURE COMMUNICATIONS (2023)

添加到收藏夹

Review Cell Biology

The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies

Heidi Braumueller et al.

Summary: Colorectal cancer (CRC) is a common tumor with limited treatment options. It is a genetic disease with mutations in specific oncogenes and tumor suppressor genes, as well as a multifactorial disease involving environmental factors. The cytokine networks between cancer cells, tumor microenvironment (TME), and microbiome are important in regulating tumor growth, metastasis, and treatment resistance in CRC.

CELLS (2023)

添加到收藏夹

Article Multidisciplinary Sciences

Structural mechanisms for regulation of GSDMB pore-forming activity

Xiu Zhong et al.

Summary: Cytotoxic lymphocyte-derived granzyme A (GZMA) cleaves GSDMB, a gasdermin-family pore-forming protein, to trigger target cell pyroptosis. This study reveals the mechanism of how the Shigella flexneri ubiquitin-ligase virulence factor IpaH7.8 targets both GSDMB and GSDMD. The study also highlights the influence of different splicing isoforms of GSDMB on pyroptotic activity.

NATURE (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

NIR-II laser-mediated photo-Fenton-like reaction via plasmonic Cu9S8 for immunotherapy enhancement

Lu An et al.

Summary: Chemodynamic therapy (CDT) is a method used to modulate the tumor microenvironment and extend the benefits of immune checkpoint therapy. A Near-Infrared (NIR)-II laser-mediated photoFenton-like reaction was proposed as an enhancement strategy to enhance the immune response. The experimental results show that this strategy effectively induces immunogenic cell death and dendritic cell maturation.

NANO TODAY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bimetallic oxide Cu1.5Mn1.5O4 cage-like frame nanospheres with triple enzyme-like activities for bacterial-infected wound therapy

Konglin Wu et al.

Summary: In this study, bimetallic oxide Cu1.5Mn1.5O4 cage-like nanospheres with a special mesoporous cavity structure were synthesized, exhibiting enhanced triple enzyme-like activities and potential applications in antibacterial therapy and wound disinfection.

NANO TODAY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Real-Time Detection of Hydroxyl Radical Generated at Operating Electrodes via Redox-Active Adduct Formation Using Scanning Electrochemical Microscopy

Jaxiry S. Barroso-Martinez et al.

Summary: The hydroxyl radical (•OH) is a highly attractive reactive oxygen species with potential applications in efficient wastewater treatment and electrosynthesis. However, its short lifetime poses challenges for in situ detection. In this study, we used spin traps and electron spin resonance to detect •OH in solution. We also developed a scanning electrochemical microscopy technique to detect its generation in real time from electrode surfaces. Our findings provide valuable insights for the detection and exploration of •OH in oxidation processes at electrode surfaces.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Engineering, Biomedical

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

Boyi Niu et al.

Summary: Glutathione (GSH) plays a crucial role in cellular antioxidative system, particularly in cancer cells, where a high level of GSH is essential for scavenging ROS and detoxifying xenobiotics. Depletion of GSH has been shown to enhance the efficacy of various therapies such as ROS-based therapy, ferroptosis, and chemotherapy. This review comprehensively discusses the importance of GSH depletion in cancer therapy and various strategies employed to achieve it.

BIOMATERIALS (2021)

添加到收藏夹

Article Engineering, Biomedical

Cancer immunogenic cell death via photo-pyroptosis with light-sensitive Indoleamine 2,3-dioxygenase inhibitor conjugate

Yang Lu et al.

Summary: NBS-1MT, an organic photo-immune activator, effectively triggers pyroptosis and disrupts the suppressive tumor microenvironment, activating the immune response and inhibiting tumor growth.

BIOMATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Constructing Electron Levers in Perovskite Nanocrystals to Regulate the Local Electron Density for Intensive Chemodynamic Therapy

Peiran Zhao et al.

Summary: By regulating the electron density of reaction center atoms, this study has successfully increased the catalytic activity of Fe, reduced the activation energy of the Fenton reaction, and increased the (OH)-O- production rate. This provides a new possibility for highly effective chemodynamic therapy.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Medicine, Research & Experimental

Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment

Sheng-Kai Hsu et al.

Summary: New types of programmed cell death, such as ferroptosis, necroptosis, and pyroptosis, have emerged in recent years, playing significant roles in cancer progression modulation and being closely related to immune regulation in the tumor microenvironment. Pyroptosis, in particular, has been identified as crucial for host defense and bridging innate and adaptive immunity, showing benefits for cancer immunotherapies.

THERANOSTICS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

A bioorthogonal system reveals antitumour immune function of pyroptosis

Qinyang Wang et al.

NATURE (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Nanozyme-based catalytic theranostics

Yanan Zhang et al.

RSC ADVANCES (2020)

添加到收藏夹

Review Multidisciplinary Sciences

A view on drug resistance in cancer

Neil Vasan et al.

NATURE (2019)

添加到收藏夹

Article Cell Biology

Assessment of the Immunosuppressive Potential of INF-γ Licensed Adipose Mesenchymal Stem Cells, Their Secretome and Extracellular Vesicles

Teresa Raquel Tavares Serejo et al.

CELLS (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

All-in-One Theranostic Nanoagent with Enhanced Reactive Oxygen Species Generation and Modulating Tumor Microenvironment Ability for Effective Tumor Eradication

Yang Liu et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Large Hollow Cavity Luminous Nanoparticles with Near-Infrared Persistent Luminescence and Tunable Sizes for Tumor Afterglow Imaging and Chemo-/Photodynamic Therapies

Jun Wang et al.

ACS NANO (2018)

添加到收藏夹

Article Engineering, Environmental

Surface Facet of CuFeO2 Nanocatalyst: A Key Parameter for H2O2 Activation in Fenton-Like Reaction and Organic Pollutant Degradation

Chu Dai et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2018)

添加到收藏夹

Article Multidisciplinary Sciences

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang et al.

NATURE (2017)

添加到收藏夹

Article Chemistry, Physical

Fe-g-C3N4/graphitized mesoporous carbon composite as an effective Fenton-like catalyst in a wide pH range

Jianqing Ma et al.

APPLIED CATALYSIS B-ENVIRONMENTAL (2017)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrasound-Induced Reactive Oxygen Species Mediated Therapy and Imaging Using a Fenton Reaction Activable Polymersome

Wei-Peng Li et al.

ACS NANO (2016)

添加到收藏夹

Article Environmental Sciences

Copper-promoted circumneutral activation of H2O2 by magnetic CuFe2O4 spinel nanoparticles: Mechanism, stoichiometric efficiency, and pathway of degrading sulfanilamide

Yong Feng et al.

CHEMOSPHERE (2016)

添加到收藏夹

Review Toxicology

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

Krishnendu Sinha et al.

ARCHIVES OF TOXICOLOGY (2013)

添加到收藏夹

Correction Multidisciplinary Sciences

A role for mitochondria in NLRP3 inflammasome activation (vol 469, pg 221, 2011)

Rongbin Zhou et al.

NATURE (2011)

添加到收藏夹

Review Biochemistry & Molecular Biology

Pattern Recognition Receptors and Inflammation

Osamu Takeuchi et al.

CELL (2010)

添加到收藏夹

Article Genetics & Heredity

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

Rajan P. Nair et al.

NATURE GENETICS (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

K Ito et al.

NATURE MEDICINE (2006)

添加到收藏夹

Article Biochemical Research Methods

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

Irfan Rahman et al.

NATURE PROTOCOLS (2006)

添加到收藏夹

Review Oncology

Hypoxia - A key regulatory factor in tumour growth

AL Harris

NATURE REVIEWS CANCER (2002)

添加到收藏夹

Article Multidisciplinary Sciences

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

L Alexopoulou et al.

NATURE (2001)

添加到收藏夹

Review Multidisciplinary Sciences

Oxidants, oxidative stress and the biology of ageing

T Finkel et al.

NATURE (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.