相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis
Kate Sowerby et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2023)
Use of benznidazole to treat chronic Chagas disease: An updated systematic review with a meta-analysis
Clara Crespillo-Andujar et al.
PLOS NEGLECTED TROPICAL DISEASES (2022)
Chagas Disease: Chronic Chagas Cardiomyopathy
Natalia Giraldo Echavarria et al.
CURRENT PROBLEMS IN CARDIOLOGY (2021)
Trypanothione Metabolism as Drug Target for Trypanosomatids
Maria Dolores Pineyro et al.
CURRENT PHARMACEUTICAL DESIGN (2021)
Biosynthesis, Quantification and Genetic Diseases of the Smallest Signaling Thiol Metabolite: Hydrogen Sulfide
Joanna Myszkowska et al.
ANTIOXIDANTS (2021)
Transplantation for Chagas Heart Disease: a Comprehensive Review
Fernando Bacal et al.
CURRENT TRANSPLANTATION REPORTS (2021)
Targeting Trypanothione Reductase, a Key Enzyme in the Redox Trypanosomatid Metabolism, to Develop New Drugs against Leishmaniasis and Trypanosomiases
Theo Battista et al.
MOLECULES (2020)
Recent Advancement in the Search of Innovative Antiprotozoal Agents Targeting Trypanothione Metabolism
Francesco Saccoliti et al.
CHEMMEDCHEM (2020)
American trypanosomiasis (Chagas disease) in solid organ transplantation
Marcelo Radisic et al.
TRANSPLANT INFECTIOUS DISEASE (2020)
Chagas cardiomyopathy and heart failure: From epidemiology to treatment
Erico Santos et al.
REVISTA PORTUGUESA DE CARDIOLOGIA (2020)
Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol
Maria L. Cafferata et al.
REPRODUCTIVE HEALTH (2020)
Dual and Opposite Roles of Reactive Oxygen Species (ROS) in Chagas Disease: Beneficial on the Pathogen and Harmful on the Host
Edio Maldonado et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
Drug Target Selection for Trypanosoma cruzi Metabolism by Metabolic Control Analysis and Kinetic Modeling
Emma Saavedra et al.
CURRENT MEDICINAL CHEMISTRY (2019)
Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity
Zabdi Gonzalez-Chavez et al.
REDOX BIOLOGY (2019)
Hyperhomocysteinemia as a Risk Factor and Potential Nutraceutical Target for Certain Pathologies
Caterina Tinelli et al.
FRONTIERS IN NUTRITION (2019)
Chagas heart disease: A contemporary review
Alejandro Velasco et al.
JOURNAL OF NUCLEAR CARDIOLOGY (2018)
Buthionine sulfoximine is a multitarget inhibitor of trypanothione synthesis in Trypanosomacruzi
Citlali Vazquez et al.
FEBS LETTERS (2017)
Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the EPIC-Oxford cohort
J. A. Schmidt et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2016)
Expanding the tool box for genetic manipulation of Trypanosoma cruzi
Gabriela de Assis Burle-Caldas et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2015)
Cystathionine γ- lyase, an Enzyme Related to the Reverse Transsulfuration Pathway, is Functional in Leishmania spp
Lucila Giordana et al.
JOURNAL OF EUKARYOTIC MICROBIOLOGY (2014)
A fluorescent probe for intracellular cysteine overcoming the interference by glutathione
Minggang Tian et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Trypanosoma cruzi Antioxidant Enzymes As Virulence Factors in Chagas Disease
Lucia Piacenza et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Drug target validation of the trypanothione pathway enzymes through metabolic modelling
Viridiana Olin-Sandoval et al.
FEBS JOURNAL (2012)
Functional characterization of enzymes involved in cysteine biosynthesis and H2S production in Trypanosoma cruzi
Daniela Marciano et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2012)
Shotgun Sequencing Analysis of Trypanosoma cruzi I Sylvio X10/1 and Comparison with T. cruzi VI CL Brener
Oscar Franzen et al.
PLOS NEGLECTED TROPICAL DISEASES (2011)
Targeting Trypanothione Metabolism in Trypanosomatid Human Parasites
Viridiana Olin-Sandoval et al.
CURRENT DRUG TARGETS (2010)
Characterization of Trypanosoma cruzi l-cysteine transport mechanisms and their adaptive regulation
Gaspar E. Canepa et al.
FEMS MICROBIOLOGY LETTERS (2009)
Structural Basis for the Inhibition Mechanism of Human Cystathionine γ-Lyase, an Enzyme Responsible for the Production of H2S
Qingxiang Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values
Julie Furne et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2008)
Metabolic control analysis: A tool for designing strategies to manipulate metabolic pathways
Rafael Moreno-Sanchez et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2008)
The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements
Eva Gluenz et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2007)
Protein production by auto-induction in high-density shaking cultures
FW Studier
PROTEIN EXPRESSION AND PURIFICATION (2005)
Glycolysis in Entamoeba histolytica -: Biochemical characterization of recombinant glycolytic enzymes and flux control analysis
E Saavedra et al.
FEBS JOURNAL (2005)
Cystathionine β-synthase:: Structure, function, regulation, and location of homocystinuria-causing mutations
EW Miles et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Visualization of PLP-bound intermediates in hemeless variants of human cystathionine β-synthase:: evidence that lysine 119 is a general base
R Evande et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2004)
The Mathematics of Metabolic Control Analysis revisited
D Visser et al.
METABOLIC ENGINEERING (2002)
Metabolic control analysis in drug discovery and disease
M Cascante et al.
NATURE BIOTECHNOLOGY (2002)
Characterization of transsulfuration and cysteine biosynthetic pathways in the protozoan hemoflagellate, Trypanosoma cruzi -: Isolation and molecular characterization of cystathionine β-synthase and serine acetyltransferase from Trypanosoma
T Nozaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)