4.5 Article

Paxillin/HDAC6 regulates microtubule acetylation to promote directional migration of keratinocytes driven by electric fields

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Emergency Medicine

CD9 negatively regulates collective electrotaxis of the epidermal monolayer by controlling and coordinating the polarization of leader cells

Xiaoqiang Liu et al.

Summary: This study investigates the mechanism of polarization and coordination of leader cells during electrotactic collective migration. The results demonstrate that CD9 plays a crucial role by controlling and coordinating the polarization of leader cells through the ADAM17/HB-EGF/EGFR signaling pathway.

BURNS & TRAUMA (2023)

Article Gastroenterology & Hepatology

Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the Histone Deacetylase 6/Tripartite Motif Containing 28/Zinc Finger Protein 354C Corepressor Complex

Zhe Li et al.

Summary: In this study, a novel antisense lncRNA, LINC00624, was identified in hepatocellular carcinoma, which promotes tumor growth and metastasis by disrupting the formation of the HDAC6-TRIM28-ZNF354C transcriptional corepressor complex and releasing transcriptional inhibition on CHD1L and BCL9 genes.

HEPATOLOGY (2021)

Review Engineering, Biomedical

Accelerated Skin Wound Healing by Electrical Stimulation

Ruizeng Luo et al.

Summary: When the integrity of the skin is compromised, an endogenous electric field is generated to facilitate wound healing, while exogenous electric fields can assist in treating wounds that cannot heal on their own. The effects of exogenous electrical stimulation on wound healing involve inflammation, blood flow, cell proliferation and migration, and wound scarring. New electrical stimulation methods and devices are characterized by being safe, low-cost, stable, and small in size.

ADVANCED HEALTHCARE MATERIALS (2021)

Article Cell Biology

Tubulin acetylation promotes penetrative capacity of cells undergoing radial intercalation

Caitlin Collins et al.

Summary: Post-translational modification of tubulin plays a crucial role in regulating the penetrative capacity of cells undergoing radial intercalation. Modulating tubulin acetylation in intercalating cells alters developmental timing, with more acetylation leading to faster penetration. Cells preferentially penetrate higher-order vertices over tricellular vertices, indicating that lower-order vertices are more restrictive sites of insertion. Increasing tubulin acetylation shifts the accessibility of intercalating cells towards more restrictive junctions, as described by a geometric-based mathematical model.

CELL REPORTS (2021)

Article Cell Biology

The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration

Nader Rahimi et al.

Summary: TMIGD1 interacts with ERM family proteins moesin and ezrin, regulating their cellular localization and impacting cell morphology, migration, and mitotic spindle organization. The findings provide a molecular framework for understanding the complex functional interplay between TMIGD1 and ERM family proteins in the regulation of cell adhesion and mitotic spindle assembly, with implications in physiological and pathological processes such as cancer progression.

JOURNAL OF BIOMEDICAL SCIENCE (2021)

Review Cell & Tissue Engineering

Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization

Tong Xiao et al.

STEM CELL RESEARCH & THERAPY (2020)

Article Cell Biology

Polarization of ADAM17-driven EGFR signalling in electric field-guided collective migration of epidermal sheets

Naixin Jia et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)

Review Pharmacology & Pharmacy

Electric field-responsive nanoparticles and electric fields: physical, chemical, biological mechanisms and therapeutic prospects

Jelena Kolosnjaj-Tabi et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Article Biochemistry & Molecular Biology

DYRK1B regulates Hedgehog-induced microtubule acetylation

Rajeev Singh et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Article Cell Biology

Microtubules and Microtubule-Associated Proteins

Holly Goodson et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)

Review Emergency Medicine

Electrically stimulated cell migration and its contribution to wound healing

Guangping Tai et al.

BURNS & TRAUMA (2018)

Review Biochemistry & Molecular Biology

Tubulin Post-Translational Modifications and Microtubule Dynamics

Dorota Wloga et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Review Oncology

Paxillin: a crossroad in pathological cell migration

Ana Mara Lopez-Colome et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)

Article Cell Biology

Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration

Fatemeh Dubois et al.

MOLECULAR BIOLOGY OF THE CELL (2017)

Review Biochemistry & Molecular Biology

Causes and Consequences of Microtubule Acetylation

Carsten Janke et al.

CURRENT BIOLOGY (2017)

Article Obstetrics & Gynecology

Acetylated α-tubulin is reduced in individuals with poor sperm motility

Shweta Bhagwat et al.

FERTILITY AND STERILITY (2014)

Review Cell Biology

Wound repair and regeneration: Mechanisms, signaling, and translation

Sabine A. Eming et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Review Cell Biology

Microtubules in Cell Migration

Sandrine Etienne-Manneville

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 29 (2013)

Article Biochemistry & Molecular Biology

Extracellular Signal-regulated Kinase (ERK) Phosphorylates Histone Deacetylase 6 (HDAC6) at Serine 1035 to Stimulate Cell Migration

Kendra A. Williams et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Biotechnology & Applied Microbiology

Current Aspects in the Pathophysiology and Treatment of Chronic Wounds in Diabetes Mellitus

Elena Tsourdi et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Review Surgery

Wound Repair and Regeneration

J. M. Reinke et al.

EUROPEAN SURGICAL RESEARCH (2012)

Article Biochemistry & Molecular Biology

Opposing Roles for TRAF1 in the Alternative versus Classical NF-κB Pathway in T Cells

Ann J. McPherson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Cell Biology

Nonpolarized signaling reveals two distinct modes of 3D cell migration

Ryan J. Petrie et al.

JOURNAL OF CELL BIOLOGY (2012)

Article Cell Biology

Electric fields guide migration of epidermal stem cells and promote skin wound healing

Li Li et al.

WOUND REPAIR AND REGENERATION (2012)

Article Biology

Extracellular Electrical Fields Direct Wound Healing and Regeneration

Mark A. Messerli et al.

BIOLOGICAL BULLETIN (2011)

Article Biochemistry & Molecular Biology

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

David Kaluza et al.

EMBO JOURNAL (2011)

Review Biotechnology & Applied Microbiology

The Role of HDAC6 in Cancer

Grace I. Aldana-Masangkay et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

Article Cell Biology

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis

Nicholas O. Deakin et al.

MOLECULAR BIOLOGY OF THE CELL (2011)

Article Cell & Tissue Engineering

Electrically Guiding Migration of Human Induced Pluripotent Stem Cells

Jiaping Zhang et al.

STEM CELL REVIEWS AND REPORTS (2011)

Article Rehabilitation

Electrical Stimulation Therapy Increases Rate of Healing of Pressure Ulcers in Community-Dwelling People With Spinal Cord Injury

Pamela E. Houghton et al.

ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION (2010)

Article Cell Biology

Post-translational modifications of microtubules

Dorota Wloga et al.

JOURNAL OF CELL SCIENCE (2010)

Review Dentistry, Oral Surgery & Medicine

Factors Affecting Wound Healing

S. Guo et al.

JOURNAL OF DENTAL RESEARCH (2010)

Review Oncology

The cytoskeleton and cancer

Alan Hall

CANCER AND METASTASIS REVIEWS (2009)

Article Cell Biology

Wound repair at a glance

Tanya J. Shaw et al.

JOURNAL OF CELL SCIENCE (2009)

Review Cell Biology

Electrical fields in wound healing-An overriding signal that directs cell migration

Min Zhao

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2009)

Article Cell Biology

Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites

Andrey Efimov et al.

JOURNAL OF CELL SCIENCE (2008)

Review Cell Biology

HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions

Agustin Valenzuela-Fernandez et al.

TRENDS IN CELL BIOLOGY (2008)

Review Physiology

Paxillin: Adapting to change

MC Brown et al.

PHYSIOLOGICAL REVIEWS (2004)

Review Cell Biology

Post-translational modifications regulate microtubule function

S Westermann et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)

Article Multidisciplinary Sciences

HDAC6 is a microtubule-associated deacetylase

C Hubbert et al.

NATURE (2002)

Review Cell Biology

Paxillin and focal adhesion signalling

CE Turner

NATURE CELL BIOLOGY (2000)