期刊
JOURNAL OF THEORETICAL BIOLOGY
卷 576, 期 -, 页码 -出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jtbi.2023.111655
关键词
S-systems; Biochemical systems theory; Design principles; Systems biology; Systems design space analysis; Mathematically controlled comparisons; Robustness; Canonical nonlinear forms
Michael Savageau's Biochemical Systems Analysis papers have had a significant impact on Systems Biology, generating core concepts and tools. This article provides a brief summary of these papers and discusses the most relevant developments in Biochemical Systems Theory since their publication.
Michael Savageau's Biochemical Systems Analysis I, II, III papers, published in volumes 25 and 26 of the journal, kickstarted a research programme that originated many of the core concepts and tools of Systems Biology. This article briefly summarizes these papers and discusses the most relevant developments in Biochemical Systems Theory since their publication.
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