Effects of melancholic features on positive and negative suicidal ideation in patients with treatment-resistant depression and strong suicidal ideation receiving low-dose ketamine infusion

Article Psychiatry

Societal factors and psychological distress indicators associated with the recent rise in youth suicide in Taiwan: A time trend analysis

Yi-Han Chang et al.

Summary: Youth suicide rates and the prevalence of suicidal behaviors have been increasing in Taiwanese youth since the 2010s. These increases may be associated with parental divorce rates, Internet use, and poor sleep.

AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY (2023)

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Article Clinical Neurology

A Randomized, Double-Blind, Midazolam-Controlled Trial of Low-Dose Ketamine Infusion in Patients With Treatment-Resistant Depression and Prominent Suicidal Ideation

Tung-Ping Su et al.

Summary: This study suggests that low-dose ketamine infusion is a safe and effective treatment for patients with TRD and prominent suicidal ideation. The timing of ketamine administration, specifically the duration of the current depressive episode and the number of failed antidepressant trials, plays an important role in achieving therapeutic response.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2023)

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Article Medicine, General & Internal

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial

Mocrane Abbar et al.

Summary: The objective of this study was to confirm the rapid onset anti-suicidal benefits of ketamine in the short term and at six weeks, overall and according to diagnostic group. A double blind, randomized, placebo controlled trial was conducted on 156 participants. The results showed a higher rate of complete suicidal remission in the ketamine group on day 3.

BMJ-BRITISH MEDICAL JOURNAL (2022)

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Review Medicine, General & Internal

Suicide and self-harm

Duleeka Knipe et al.

Summary: Suicide and self-harm are major health and societal issues worldwide, with a higher burden observed in low-income and middle-income countries. The causes of these behaviors are multifactorial, influenced by factors such as gender, age, ethnicity, and geography. Clinical and public health interventions offer promise, but their effectiveness has mostly been studied in high-income countries. Predicting suicide is unlikely to be helpful, and intervention and prevention efforts should involve both clinical and community approaches, involving every healthcare professional.

LANCET (2022)

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Review Psychiatry

Prevalence and Correlates of Suicide and Nonsuicidal Self-injury in Children A Systematic Review and Meta-analysis

Richard T. Liu et al.

Summary: Considerably less is known about self-injurious thoughts and behaviors (SITBs) in preadolescence than older age groups, but the prevalence of preadolescent suicide has increased in recent years. This study aims to assess the prevalence and correlates of preadolescent SITBs, as well as compare them with adolescent SITBs in terms of associated characteristics.

JAMA PSYCHIATRY (2022)

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Review Psychiatry

Ketamine as a prophylactic resilience-enhancing agent

Audrey G. Evers et al.

Summary: Stress exposure is a major risk factor for psychiatric illnesses. This review explores the potential pro-resilience effect of ketamine in rodents and its preliminary evidence as a prophylactic treatment for postpartum depression in humans. Animal studies have shown that ketamine given prior to a stressor can protect against depressive-like behavior. Similar protective effects have been observed against PTSD-like behavior. Recent research also found that ketamine administration immediately after caesarian-section significantly reduced the prevalence of postpartum depression.

FRONTIERS IN PSYCHIATRY (2022)

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Article Biochemistry & Molecular Biology

International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators

Rebecca B. Price et al.

Summary: Ketamine has rapid antidepressant effects and can reduce depressive symptoms in a variety of patients. It is particularly effective in patients who have been resistant to previous medications. However, there are currently no specific clinical or demographic characteristics that can guide treatment decisions for ketamine.

MOLECULAR PSYCHIATRY (2022)

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Article Psychiatry

Suicide Risk and Protective Factors: A Network Approach

Mikayla S. Holman et al.

Summary: This study examines the interactions between risk and protective factors for suicide using network analysis and identifies the most central factors in this network. The findings highlight the importance of considering both risk and protective factors when assessing an individual's suicide risk.

ARCHIVES OF SUICIDE RESEARCH (2022)

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Article Neurosciences

Predictors of change in suicidal ideation across treatment phases of major depressive disorder: analysis of the STAR*D data

Cory R. Weissman et al.

Summary: The study analyzed STAR*D trial data and found that factors such as history of suicide attempts, comorbid medical illness, and family history of drug abuse can impact changes in suicidal ideation. Treatment with bupropion and buspirone was associated with reduction in suicidal ideation. Improvement in suicidal ideation was correlated with improvement in overall depression symptoms.

NEUROPSYCHOPHARMACOLOGY (2021)

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Article Psychology, Clinical

Happiness During Low-Dose Ketamine Infusion Predicts Treatment Response: Reexploring the Adjunctive Ketamine Study of Taiwanese Patients With Treatment-Resistant Depression

Mu-Hong Chen et al.

JOURNAL OF CLINICAL PSYCHIATRY (2020)

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Review Neurosciences

Translating Molecular and Neuroendocrine Findings in Posttraumatic Stress Disorder and Resilience to Novel Therapies

Jonathan DePierro et al.

BIOLOGICAL PSYCHIATRY (2019)

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Article Psychiatry

Association between depression subtypes and response to repeated-dose intravenous ketamine

C. Wang et al.

ACTA PSYCHIATRICA SCANDINAVICA (2019)

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Article Psychiatry

Circulating Levels of Brain-Derived Neurotrophic Factor and History of Suicide Attempts in Women

Anastacia Y. Kudinova et al.

SUICIDE AND LIFE-THREATENING BEHAVIOR (2019)

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Article Psychiatry

Ketamine for Rapid Reduction of Suicidal Thoughts in Major Depression: A Midazolam-Controlled Randomized Clinical Trial

Michael F. Grunebaum et al.

AMERICAN JOURNAL OF PSYCHIATRY (2018)

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Article Psychiatry

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

Samuel T. Wilkinson et al.

AMERICAN JOURNAL OF PSYCHIATRY (2018)

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Article Clinical Neurology

Major Depression and the Degree of Suicidality: Results of the European Group for the Study of Resistant Depression (GSRD)

Markus Dold et al.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2018)

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Review Biochemistry & Molecular Biology

Mechanisms of ketamine action as an antidepressant

P. Zanos et al.

MOLECULAR PSYCHIATRY (2018)

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Review Psychiatry

Brain derived neurotrophic factor (BDNF) and suicidal behavior: A review of studies from Asian countries

Akanksha Sonal et al.

ASIAN JOURNAL OF PSYCHIATRY (2018)

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Article Neurosciences

Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression

Tung-Ping Su et al.

NEUROPSYCHOPHARMACOLOGY (2017)

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Article Multidisciplinary Sciences

The Major Depressive Disorder Hierarchy: Rasch Analysis of 6 items of the Hamilton Depression Scale Covering the Continuum of Depressive Syndrome

Lucas Primo de Carvalho Alves et al.

PLOS ONE (2017)

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Article Neurosciences

Ketamine as a Prophylactic Against Stress-Induced Depressive-like Behavior

Rebecca A. Brachman et al.

BIOLOGICAL PSYCHIATRY (2016)

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Review Medicine, General & Internal

Suicide and suicidal behaviour

Gustavo Turecki et al.

LANCET (2016)

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Article Emergency Medicine

COMPARISON OF THE EFFECTS OF KETAMINE AND MORPHINE ON PERFORMANCE OF REPRESENTATIVE MILITARY TASKS

Steven J. Gaydos et al.

JOURNAL OF EMERGENCY MEDICINE (2015)

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Article Clinical Neurology

Brief, unidimensional melancholia rating scales are highly sensitive to the effect of citalopram and may have biological validity: Implications for the Research Domain Criteria (RDoC)

Soren D. Ostergaard et al.

JOURNAL OF AFFECTIVE DISORDERS (2014)

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Article Psychiatry

Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

James W. Murrough et al.

AMERICAN JOURNAL OF PSYCHIATRY (2013)

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Article Medicine, General & Internal

Changing trends in the prevalence of common mental disorders in Taiwan: a 20-year repeated cross-sectional survey

Tiffany Szu-Ting Fu et al.

LANCET (2013)

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Review Psychiatry

Synaptic Mechanisms Underlying Rapid Antidepressant Action of Ketamine

Ege T. Kavalaii et al.

AMERICAN JOURNAL OF PSYCHIATRY (2012)

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Article Neurosciences

Resilience to Chronic Stress Is Mediated by Hippocampal Brain-Derived Neurotrophic Factor

Dekel Taliaz et al.

JOURNAL OF NEUROSCIENCE (2011)

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Review Medicine, General & Internal

Brain-derived neurotrophic factor and suicide pathogenesis

Yogesh Dwivedi

ANNALS OF MEDICINE (2010)

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Article Clinical Neurology

Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: An examination of citalopram in the STAR*D study

Sidney Zisook et al.

JOURNAL OF AFFECTIVE DISORDERS (2009)

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Article Psychology, Clinical

The Maudsley Staging Method for Treatment-Resistant Depression: Prediction of Longer-Term Outcome and Persistence of Symptoms

Abebaw Fekadu et al.

JOURNAL OF CLINICAL PSYCHIATRY (2009)

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Article Clinical Neurology

The Montgomery Asberg and the Hamilton ratings of depression: A comparison of measures

Thomas J. Carmody et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2006)

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Article Neurosciences

Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs

F Karege et al.

MOLECULAR BRAIN RESEARCH (2005)

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Article Psychiatry

Melancholia and the probability and lethality of suicide attempts

MF Grunebaum et al.

BRITISH JOURNAL OF PSYCHIATRY (2004)

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Effects of melancholic features on positive and negative suicidal ideation in patients with treatment-resistant depression and strong suicidal ideation receiving low-dose ketamine infusion

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