期刊
CHEMICAL COMMUNICATIONS
卷 59, 期 98, 页码 14555-14558出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d3cc04317g
关键词
-
We developed a simple and rational method to rank lead-likeness of molecules using continuous evaluation functions, which has proven to be competitive against known methods and has helped in selecting promising candidate molecules for epigenetic applications.
A simple and rational method to rank lead-likeness of molecules using continuous evaluation functions was hereby developed. This strategy proved to be competitive against known methods and finally helped in driving synthetic efforts towards candidates of interest for epigenetic applications against HDAC6, BRD4 and EZH2. We report a simple and rational method to rank lead-likeness of molecules using continuous evaluation functions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据