☆ 4.8 Review

Bioinspired nanomaterials for the treatment of bacterial infections

NANO RESEARCH (2023)

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Review Environmental Sciences

Nanozyme-based pollutant sensing and environmental treatment: Trends, challenges, and perspectives

Ragini Singh et al.

Summary: Nanozymes are nanomaterials that have enzyme-like properties and unique physical and chemical characteristics. They have shown great potential in environmental monitoring and remediation of pollutants, including heavy metals and organic compounds. However, their inherent toxicity needs to be evaluated and monitored to ensure their safe use.

SCIENCE OF THE TOTAL ENVIRONMENT (2023)

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Article Materials Science, Multidisciplinary

Copper-doped melanin nanozyme with enhanced photothermal and peroxidase-like catalytic property for synergistic antimicrobial effect

Xiaojing He et al.

Summary: By binding Cu2+ with melanin to form a nanozyme, the near infrared light absorption and photothermal performance of melanin were significantly enhanced. The nanozyme exhibited excellent peroxidase-like catalytic activity, converting H2O2 into toxic hydroxyl radicals. The synergistic antibacterial effect achieved through the combination of nanozyme catalysis and enhanced photothermal property could effectively kill bacteria within only 5 minutes under 808 nm laser irradiation, which holds great potential for the design of antimicrobial materials.

MATERIALS LETTERS (2023)

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Article Materials Science, Biomaterials

Tailored anti-biofilm activity-Liposomal delivery for mimic of small antimicrobial peptide

Lisa Myrseth Hemmingsen et al.

Summary: The eradication of bacteria in biofilms is a major challenge in treating chronic wounds. Antimicrobial peptides and their mimics are potential options, but their clinical use is limited. A study explored the use of a synthetic mimic of an antimicrobial peptide incorporated into liposomes to improve its anti-biofilm effect and anti-inflammatory activity. The results showed that the liposomes effectively eradicated biofilms and reduced inflammation, making them a promising therapeutic option for bacteria-infected chronic wounds.

BIOMATERIALS ADVANCES (2023)

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Article Biochemistry & Molecular Biology

Gold Nanoparticles Functionalized with 2-Thiouracil for Antiproliferative and Photothermal Therapies in Breast Cancer Cells

Genesis Lorenzana-Vazquez et al.

Summary: Nanoparticles, specifically gold nanoparticles (AuNPs), have been used in cancer treatment to transport drugs to specific body parts. This study focuses on utilizing the photothermal therapy (PTT) property of gold nanoparticles, which convert light to heat and induce cellular damage, to enhance the antiproliferative activity of the anticancer compound 2-thiouracil (2-TU). The functionalization of AuNPs with 2-TU resulted in increased antiproliferative activity and the ability to reduce the drug concentration and side effects during treatment via synergistic effects.

MOLECULES (2023)

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Review Medicine, General & Internal

Immunotherapies against human bacterial and fungal infectious diseases: A review

Hafsa Qadri et al.

Summary: Ongoing struggles with infectious diseases highlight the global public health threat they pose, including the current SARS-Co-V2 outbreak. Drug-resistant pathogens have led to severe infectious diseases with rising fatality rates. To overcome the limitations of current management and control processes, new treatment solutions, such as immunotherapies, hold potential in strengthening the body's immune system to fight infections. Immunotherapies are being researched as alternative treatments for infectious diseases, improving our understanding of the relationship between pathogens and the host immune system.

FRONTIERS IN MEDICINE (2023)

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Article Engineering, Environmental

Valence-switchable and biocatalytic vanadium-based MXene nanoplatform with photothermal-enhanced dual enzyme-like activities for anti-infective therapy

Xiaoshuai Sun et al.

Summary: This study developed vanadium nitride MXene (V2N) with superior catalytic activity as a nanozyme. V2N exhibited dual enzyme-like (oxidase-like and peroxidase-like) catalytic activity and generated reactive oxygen species at the nanoscale, thus effectively eradicating bacteria in vitro and promoting the healing of subcutaneous abscesses.

CHEMICAL ENGINEERING JOURNAL (2023)

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Article Engineering, Environmental

Single-Atom-Catalyzed MXene-Based nanoplatform with Photo-Enhanced Peroxidase-Like activity nanotherapeutics for Staphylococcus aureus infection

ZhangPing Li et al.

Summary: Researchers synthesized platinum single atoms hybridized on titanium carbide MXene and demonstrated their catalytic and photothermal properties, which have potential applications in anti-infection therapy.

CHEMICAL ENGINEERING JOURNAL (2023)

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Review Chemistry, Inorganic & Nuclear

Carbon-based nanozymes: Design, catalytic mechanism, and bioapplication

Yun Sun et al.

Summary: Carbon-based nanomaterials with enzyme-like activity show great potential in biomedical applications. They have abundant active sites, excellent stability, and good biological safety. The unique optical, thermal, and acoustic properties of carbon-based nanozymes provide a multifunctional platform. This review discusses their recent research progress, challenges, and perspectives.

COORDINATION CHEMISTRY REVIEWS (2023)

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Article Medicine, Research & Experimental

Polyethylene glycol (PEG)-associated immune responses triggered by clinically relevant lipid nanoparticles in rats

Haiyang Wang et al.

npj Vaccines (2023)

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Review Chemistry, Multidisciplinary

Recent Advances in Nanozymes: From Matters to Bioapplications

Yongjian Ai et al.

Summary: The article summarizes the latest developments in nanozyme research, including the preparation of different raw materials, the various enzyme-like catalytic activities of nanozymes, and their wide-ranging biological applications. Additionally, it outlines the current challenges faced by nanozymes and offers future research directions.

ADVANCED FUNCTIONAL MATERIALS (2022)

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Article Chemistry, Multidisciplinary

Peroxidase-Mimetic Copper-Doped Carbon-Dots for Oxidative Stress-Mediated Broad-Spectrum and Efficient Antibacterial Activity

Yuhui Wang et al.

Summary: This study presents a new strategy for the design of antimicrobial nano-agents using Cu-doped CDs. The Cu-CDs showed superior antimicrobial activity by triggering oxidative stress and membrane disruption.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

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Article Chemistry, Multidisciplinary

A Self-Assembled Fmoc-Diphenylalanine Hydrogel-Encapsulated Pt Nanozyme as Oxidase- and Peroxidase-Like Breaking pH Limitation for Potential Antimicrobial Application

Jun Chen et al.

Summary: A novel approach using Fmoc-FF hydrogel to enhance the oxidase and peroxidase-like activities of nanozymes at neutral or alkaline pH levels is proposed, resulting in 6 to 26-fold increased activity. This design breaks the pH limitation of nanozymes and promotes their biological applications.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

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Article Biotechnology & Applied Microbiology

Synthesis of taurine-Cu3(PO4)2 hybrid nanoflower and their peroxidase-mimic and antimicrobial properties

Sevim Gokce Yilmaz et al.

Summary: In this study, taurine-incorporated hybrid nanoflowers with peroxidase-mimic and antimicrobial activities were synthesized. The effects of taurine concentration, metal ion types, and pH values on the formation of nanoflowers were systematically investigated. The efficient reaction of nanoflowers can be attributed to their porous structure and the presence of transition metal ions. Moreover, the nanoflowers exhibited remarkable antimicrobial properties.

JOURNAL OF BIOTECHNOLOGY (2022)

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Article Materials Science, Multidisciplinary

Comparative analysis of synthesis, characterization, antimicrobial, antioxidant, and enzyme inhibition potential of roses petal based synthesized copper oxide nanoparticles

Madiha Asghar et al.

Summary: This study compares the physicochemical and biological properties of copper oxide nanoparticles synthesized from different species of roses. The results show that the size and structure of the nanoparticles are influenced by the plant species, and R.k-CuO NPs exhibit higher antioxidant and inhibitory potentials, suggesting potential biomedical applications.

MATERIALS CHEMISTRY AND PHYSICS (2022)

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Article Medicine, Research & Experimental

Mild Hyperthermia Induced by Hollow Mesoporous Prussian Blue Nanoparticles in Alliance with a Low Concentration of Hydrogen Peroxide Shows Powerful Antibacterial Effect

Yuting Li et al.

Summary: This article introduces a treatment strategy that uses hollow mesoporous Prussian blue nanoparticles in combination with hydrogen peroxide to induce mild hyperthermia, which shows a powerful inhibition effect on bacteria and promotes wound healing.

MOLECULAR PHARMACEUTICS (2022)

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Article Chemistry, Multidisciplinary

Haloperoxidase-mimicking CeO2-x nanorods for the deactivation of human coronavirus OC43

Jiayan Lang et al.

Summary: CeO2-x nanorods with optimized aspect ratio demonstrated strong antiviral efficacies against human coronavirus OC43.

NANOSCALE (2022)

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Article Chemistry, Analytical

SARS-CoV-2 detection with aptamer-functionalized gold nanoparticles

Srivatsa Aithal et al.

Summary: The study introduces a rapid detection test for SARS-CoV-2 utilizing nanoprobes functionalized with specific aptamer to identify spike membrane protein. The nanoprobes successfully detect spike protein concentrations of 16 nM and higher.

TALANTA (2022)

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Article Engineering, Biomedical

Cholesterol Microdomain Enhances the Biofilm Eradication of Antibiotic Liposomes

Jianjun Xie et al.

Summary: Resistance and tolerance of biofilms to antibiotics pose a major challenge in bacterial infection treatment. This study develops biofilm-targeted antibiotic liposomes by adjusting their cholesterol content, resulting in enhanced antibacterial and biofilm eradication effects. The improved effect is attributed to effective drug release through the pores formed by cholesterol microdomains in liposomes combining with membrane-damaged toxins in biofilms.

ADVANCED HEALTHCARE MATERIALS (2022)

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Article Materials Science, Biomaterials

Fabrication of a Lignin-Copper Sulfide-Incorporated PVA Hydrogel with Near-Infrared-Activated Photothermal/Photodynamic/Peroxidase-like Performance for Combating Bacteria and Biofilms

Yuanxiang Xie et al.

Summary: This study addresses the challenges of antibiotic-resistant bacteria and biofilms by fabricating a LS-CuS@PVA composite hydrogel. The LS-CuS@PVA hydrogel exhibits excellent antibacterial and antibiofilm activity under near-infrared light irradiation, attributed to the synergistic effects of photothermal and photodynamic effects, as well as reactive oxygen species.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2022)

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Article Multidisciplinary Sciences

An imidazolium-based zwitterionic polymer for antiviral and antibacterial dual functional coatings

Pengyu Chen et al.

Summary: A zwitterionic polymer was designed and synthesized to achieve contact deactivation of coronavirus in dry ambient conditions and reduce virus adhesion and bacterial biofilm formation in wet conditions. The polymer was produced using a substrate-independent and solvent-free process and can be applied to various substrates.

SCIENCE ADVANCES (2022)

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Article Pharmacology & Pharmacy

Reversible regulation of enzyme-like activity of molybdenum disulfide quantum dots for colorimetric pharmaceutical analysis

Juan Tan et al.

Summary: This study presents a new strategy for reversible regulation of nanozyme activity by using MoS2 quantum dots as building blocks. The presence of Fe3+ enhances the peroxidase-like activity of the nanozyme, while the addition of captopril inhibits this enhancement. Based on this finding, a colorimetric method for captopril detection is developed, which is simple, rapid, reliable, and low-cost, and can be read with a smartphone.

JOURNAL OF PHARMACEUTICAL ANALYSIS (2022)

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Article Nanoscience & Nanotechnology

Superoxide Radical-Mediated Self-Synthesized Au/MoO3-x Hybrids with Enhanced Peroxidase-like Activity and Photothermal Effect for Anti-MRSA Therapy

Mengyu Cao et al.

Summary: There has been a rapid increase in MRSA infections in recent years, with high mortality rates due to delayed wound healing caused by biofilms formed by MRSA. This study developed a self-synthesis strategy to prepare a plasmonic-semiconductor hybrid, Au-doped MoO3-x (Au/MoO3-x), for the elimination of MRSA infections. The hybrid exhibited high efficiency in eliminating MRSA bacteria and showed excellent biosafety.

ACS APPLIED MATERIALS & INTERFACES (2022)

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Article Engineering, Environmental

Manganese single-atom catalysts for catalytic-photothermal synergistic anti-infected therapy

Wang Xu et al.

Summary: This study develops a novel photothermal-catalytic antibacterial therapy using spherical mesoporous manganese single atom catalysts (Mn SACs) to treat bacteria-infected inflammation. The results demonstrate that this approach has better antibacterial effect against Escherichia coli and Staphylococcus aureus, and shows great biocompatibility for in vivo therapy.

CHEMICAL ENGINEERING JOURNAL (2022)

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Review Engineering, Chemical

Biomimetic Metallic Nanostructures for Biomedical Applications, Catalysis, and Beyond

Mohammad Tavakkoli Yaraki et al.

Summary: Nature has inspired the development of green and sustainable nanomaterials with biomimetic functions. These biomimetic metallic nanostructures, synthesized from natural resources such as plant extracts and bacteria, possess unique biomimetic properties including precise biorecognition, self-assembly, and enzymatic activity. They have attracted tremendous attention in fields such as healthcare, agriculture, energy, and environmental sciences.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2022)

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Article Chemistry, Multidisciplinary

cRGD enables rapid phagocytosis of liposomal vancomycin for intracellular bacterial clearance

Guanghui Li et al.

Summary: In this study, the in vivo fate and mechanism of cyclic RGD peptide functionalized liposome (cRGD-sLip) were investigated. It was found that cRGD-sLip demonstrated effective targeted drug delivery to bacteria-infected macrophages, improving the therapeutic efficacy of existing antibiotics in the treatment of intracellular bacterial infection.

JOURNAL OF CONTROLLED RELEASE (2022)

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Article Engineering, Biomedical

Metal-Organic Framework Modified MoS2 Nanozyme for Synergetic Combating Drug-Resistant Bacterial Infections via Photothermal Effect and Photodynamic Modulated Peroxidase-Mimic Activity

Zi-Yang Liao et al.

Summary: The UNMS NCs exhibit efficient antibacterial activity against multidrug-resistant bacteria, with a synergistic effect of photothermal, photodynamic, and enzymatic activities, generating reactive oxygen species. They show high catalytic activity over a wide pH range, excellent antibacterial ability against ampicillin-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus, with negligible cytotoxicity.

ADVANCED HEALTHCARE MATERIALS (2022)

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Review Pharmacology & Pharmacy

Current approaches of nanomedicines in the market and various stage of clinical translation

Xiaoting Shan et al.

Summary: Compared with traditional drug therapy, nanomedicines have shown intriguing biological features that enhance therapeutic efficiency and reduce toxicity. This review provides an overview of currently launched or in-clinical-trial nanomedicines, highlighting the diversified trends in carrier types, applied indications, and mechanisms of action. Additionally, the review presents the applications of nanomedicines in the prevention, diagnosis, and treatment of various diseases, such as cancer, infections, blood disorders, cardiovascular diseases, immuno-associated diseases, and nervous system diseases. The article also offers considerations and perspectives for the research and development of nanomedicines to facilitate their translation into clinical practice.

ACTA PHARMACEUTICA SINICA B (2022)

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Article Pharmacology & Pharmacy

Evaluation of CTB-sLip for Targeting Lung Metastasis of Colorectal Cancer

Xiaoying Zhang et al.

Summary: In this study, CTB protein was successfully conjugated with PEGylated liposomes to form CTB-sLip nanocarriers. The CTB-sLip demonstrated high targeting capability to human-derived colorectal cancer cells and lung metastasis in nude mice models. However, repeated injections of CTB-sLip induced the production of antibodies, but it still showed potential for the diagnosis of lung metastasis of colorectal cancer.

PHARMACEUTICS (2022)

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Review Pharmacology & Pharmacy

Drug Nanocrystals for Active Tumor-Targeted Drug Delivery

Linwei Lu et al.

Summary: Drug nanocrystals can enhance the solubility and bioavailability of poorly water-soluble drugs, and active tumor-targeted drug delivery systems can improve the efficacy and safety of chemotherapy.

PHARMACEUTICS (2022)

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Article Chemistry, Multidisciplinary

Synergy of light-controlled Pd nanozymes with NO therapy for biofilm elimination and diabetic wound treatment acceleration

T. Huang et al.

Summary: Nanozymes and nitric oxide synergize to enhance antibacterial and antibiofilm activity, with Pd-MOF@PAzo@SNP nanoplatform showing controlled nanozyme activity under UV light and releasing NO in response to UV irradiation, exhibiting excellent outcomes in chronic wound management.

MATERIALS TODAY CHEMISTRY (2022)

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Article Medicine, General & Internal

Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019

Kevin S. Ikuta et al.

Summary: This study provides comprehensive estimates of deaths associated with 33 bacterial pathogens worldwide, highlighting the significant global health burden of bacterial infections. Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae, Klebsiella pneumoniae, and Pseudomonas aeruginosa are the top five deadliest pathogens, and the deadliest infectious syndromes and pathogens vary by location and age.

LANCET (2022)

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Article Chemistry, Analytical

A label-free biosensor for selective detection of Gram-negative bacteria based on the oxidase-like activity of cupric oxide nanoparticles

Suqi Deng et al.

Summary: A label-free biosensor based on cupric oxide nanoparticles was developed for selective detection of Gram-negative bacteria. The biosensor showed good performance in detecting bacteria in food and water samples, and a portable smartphone-based device was also designed for on-site detection.

MICROCHIMICA ACTA (2022)

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Article Chemistry, Multidisciplinary

Copper Doped Carbon Dots for Addressing Bacterial Biofilm Formation, Wound Infection, and Tooth Staining

Meng Liu et al.

Summary: Oral infectious diseases and tooth staining are major challenges in dental healthcare. Researchers have developed copper-doped carbon dots (Cu-CDs) that can inhibit bacterial adhesion and eradicate biofilms in the oral environment without causing harm to surrounding tissues. Cu-CDs also show excellent antibacterial ability against both Gram-positive and Gram-negative bacteria. In addition, Cu-CDs have a better performance in tooth whitening compared to other alternatives, with minimal damage to enamel and dentin. The biocompatible Cu-CDs have great potential for eliminating oral pathogenic biofilms and promoting oral health.

ACS NANO (2022)

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Article Chemistry, Multidisciplinary

On-demand synthesis of antiseptics at the site of infection for treatment of otitis media

Jiayan Lang et al.

Summary: Otitis media is a common reason for pediatric antibiotic prescriptions. The current treatment faces challenges such as antibiotic resistance and difficulty in drug administration. A novel local treatment method was developed, which converted a metabolic product of the pathogen into a potent antiseptic. This method showed promising results in animal experiments.

NANO TODAY (2022)

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Article Chemistry, Analytical

Sensitive plasmonic ELISA assay based on butyrylcholinesterase catalyzed hydrolysis for the detection of Staphylococcus aureus

Jing-Wen Xue et al.

Summary: This paper presents a highly sensitive ELISA method for the detection of Staphylococcus aureus (S. aureus). The method utilizes magnetic beads and gold nanoparticles to capture and quantify S. aureus through a colorimetric reaction. The method provides a high sensitivity and has the potential for both visual detection and microplate reader measurement.

SENSORS AND ACTUATORS B-CHEMICAL (2022)

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Review Chemistry, Multidisciplinary

Biomimetic Nanomaterials: Diversity, Technology, and Biomedical Applications

Kamil G. Gareev et al.

Summary: Biomimetic nanomaterials (BNMs) are functional materials that mimic the structure of natural prototypes. This review provides an overview of the classification and applications of BNMs.

NANOMATERIALS (2022)

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Article Chemistry, Physical

Carbon dots derived from folic acid as an ultra-succinct smart antimicrobial nanosystem for selective killing of S. aureus and biofilm eradication

Meizhe Yu et al.

Summary: This study developed an efficient and safe antimicrobial nanosystem that can counteract bacterial infections with responsive antibacterial behavior. The nanosystem showed excellent performance and biocompatibility, making it highly relevant for clinical applications.

CARBON (2022)

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Article Multidisciplinary Sciences

Depletable peroxidase-like activity of Fe3O4 nanozymes accompanied with separate migration of electrons and iron ions

Haijiao Dong et al.

Summary: The explicit peroxidase-like catalytic mechanism of Fe3O4 nanozymes remains unclear. In this study, the authors demonstrate the electron transfer mechanism of Fe(II) ions, which regenerate surface Fe(II) and are crucial for sustaining the peroxidase-like catalytic reaction. They also identify the phase transformation and depletion of activity after prolonged catalysis, highlighting the importance of considering both surface and internal atoms in the design and application of nanozymes.

NATURE COMMUNICATIONS (2022)

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Article Materials Science, Biomaterials

Iron oxide nanoparticles with photothermal performance and enhanced nanozyme activity for bacteria-infected wound therapy

Jiaxin Guo et al.

Summary: The article introduces a photothermal-enzymes combined antibacterial treatment platform using iron oxide nanoparticles. The nanoparticles possess peroxidase-like catalytic activity, which can produce bactericidal ·OH in a slightly acidic environment, and can kill bacteria by destroying bacterial cell membranes through the photothermal effect. This treatment method shows high antibacterial efficacy against Escherichia coli and Staphylococcus aureus, and has potential in treating infected wounds.

REGENERATIVE BIOMATERIALS (2022)

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Article Nanoscience & Nanotechnology

Bacitracin-Functionalized Dextran-MoSe2 with Peroxidase-like and Near-Infrared Photothermal Activities for Low-Temperature and Synergetic Antibacterial Applications

Tianran Lin et al.

Summary: AMP/dex-MoSe2 nanosheets were developed for low-temperature and synergetic antibacterial applications. The nanosheets combined near-infrared photothermal and peroxidase-like activities with the bacterial membrane-binding ability of an antimicrobial peptide (AMP). The production of hydroxyl radicals and antibacterial efficiency were accelerated by low-temperature heat sterilization with NIR irradiation. AMP/dex-MoSe2 showed superior antibacterial effect on Gram-negative Escherichia coli under NIR irradiation compared to other methods.

ACS APPLIED BIO MATERIALS (2022)

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Article Chemistry, Multidisciplinary

Potential antimicrobial, antidiabetic, catalytic, antioxidant and ROS/RNS inhibitory activities of Silybum marianum mediated biosynthesized copper oxide nanoparticles

Junaid Iqbal et al.

Summary: The use of medicinal plants for the synthesis of nanoparticles has several advantages and in this study, Silybum marianum was used to synthesize CuO-NPs. The synthesized nanoparticles exhibited spherical morphology, crystalline structure, and showed strong bactericidal activity, dose-dependent cytotoxicity, high antioxidant potential, and excellent enzyme inhibition potential. The findings suggest that biosynthesized CuO-NPs possess significant in vitro biological and biomedical properties.

RSC ADVANCES (2022)

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Article Chemistry, Multidisciplinary

Multi-activity cobalt ferrite/MXene nanoenzymes for drug-free phototherapy in bacterial infection treatment

Jiacheng Shi et al.

Summary: The use of CM nanoenzymes for phototherapy shows great potential in inhibiting bacterial infections. CM nanoenzymes possess photothermal and photodynamic induced phototherapy functions, as well as multi-enzyme-mimicking activities. In vitro and in vivo experiments demonstrate the significant antibacterial effects of CM nanoenzymes.

RSC ADVANCES (2022)

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Article Immunology

Assessment of Data Supporting the Efficacy of New Antibiotics for Treating Infections Caused by Multidrug-resistant Bacteria

Dafna Yahav et al.

Summary: The study assessed the data supporting FDA approval of new drugs to treat MDR bacterial infections, as well as postmarketing studies. Results showed that most drugs were initially approved based on trials evaluating infections caused by non-MDR organisms, with limited postmarketing efficacy data available.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Chemistry, Multidisciplinary

Serum protein-based nanoparticles for cancer diagnosis and treatment

Haroon Iqbal et al.

Summary: Serum protein, a versatile carrier in cancer nanomedicine, has shown superior biocompatibility and targeting capacity. Serum protein-based nanoparticles hold great potential for cancer treatment, but face challenges that need to be addressed for a bright future.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Engineering, Chemical

Silver nanoparticles as an effective antimicrobial against otitis media pathogens

Xiaojing Ma et al.

Summary: Researchers developed polyvinylpyrrolidone-coated silver nanoparticles to completely eradicate common OM pathogens and a hydrogel formulation for sustained local delivery, achieving promising antimicrobial results against bacterial OM.

AICHE JOURNAL (2021)

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Article Biochemical Research Methods

Iodine-doped carbon dots with inherent peroxidase catalytic activity for photocatalytic antibacterial and wound disinfection

XiuLi Wang et al.

Summary: The synthesized N/I-CDs exhibit good fluorescence properties and peroxidase-like activity, catalyzing the generation of reactive oxygen species under visible light and showing strong photocatalytic antibacterial activity in vitro, achieving 100% antibacterial efficiency against Staphylococcus aureus and Escherichia coli in the presence of exogenous H2O2. In vivo wound disinfection experiments demonstrate the high antibacterial efficiency, low toxicity, and potential application of N/I-CDs due to their good biocompatibility and nanozyme activity.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2021)

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Article Chemistry, Physical

NIR enhanced peroxidase-like activity of Au@CeO2 hybrid nanozyme by plasmon-induced hot electrons and photothermal effect for bacteria killing

Chuang Liu et al.

Summary: By constructing a dumbbell-shaped Au@CeO2 hybrid nanozyme with strong surface plasmon resonance response in the Near Infrared (NIR) range, the peroxidase-like activity of Au@CeO2 was significantly enhanced under 808 nm irradiation. The efficient utilization of plasmon excitation through spatially separated structure led to improved antibacterial efficacy.

APPLIED CATALYSIS B-ENVIRONMENTAL (2021)

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Article Engineering, Multidisciplinary

Bifunctional cupric oxide nanoparticle-catalyzed self-cascade oxidation reactions of ascorbic acid for bacterial killing and wound disinfection

Quan-Quan Zhuang et al.

Summary: The study demonstrated a novel antibacterial system composed of cupric oxide nanoparticles and ascorbic acid, which effectively eradicated Escherichia coli and Staphylococcus aureus without noticeable cytotoxicity to mammalian tissues. The antibacterial system killed bacteria through multiple mechanisms, mainly attributed to the generation of reactive oxygen species.

COMPOSITES PART B-ENGINEERING (2021)

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Article Green & Sustainable Science & Technology

Efficient arsenic removal by a bifunctional heterogeneous catalyst through simultaneous hydrogen peroxide (H2O2) catalytic oxidation and adsorption

Jing Su et al.

Summary: This study developed a novel heterogeneous catalytic system using manganese-doped Lanthanum oxycarbonate (MnL) to catalyze the oxidation of As(III) by H2O2 and simultaneously adsorb the generated As(V), significantly increasing the removal rate of As(III) and demonstrating a wide pH range capability for oxidation. Mechanistic studies revealed that long-lived superoxide radicals were the dominant active species for As(III) oxidation and Mn atoms with low valence states played a crucial role in providing extra active sites for radical production. The La and Mn sites in MnL efficiently immobilized the generated As(V) by forming precipitates, resulting in a final As removal efficiency of 99% even after three cycles of reutilization.

JOURNAL OF CLEANER PRODUCTION (2021)

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Article Engineering, Multidisciplinary

Engineered Biomimetic Platelet Membrane-Coated Nanoparticles Block Staphylococcus aureus Cytotoxicity and Protect Against Lethal Systemic Infection

Jwa-Kyung Kim et al.

Summary: The use of human platelet membrane-coated nanoparticles as a biomimetic decoy strategy can neutralize Staphylococcus aureus toxins, protect host cells, and enhance resistance to invasive infections.

ENGINEERING (2021)

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Article Chemistry, Physical

Progress and Perspective on Carbon-Based Nanozymes for Peroxidase-like Applications

Xingyu Wang et al.

Summary: This article discusses the peroxidase mimicry of carbon-based nanozymes, analyzing the effects of their structure and surface properties on activity, demonstrating the potential of carbon nitride quantum dot systems in nanozyme applications.

JOURNAL OF PHYSICAL CHEMISTRY LETTERS (2021)

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Article Chemistry, Multidisciplinary

Facile Separation of PEGylated Liposomes Enabled by Anti-PEG scFv

Wenjing Tang et al.

Summary: A facile PEG-scFv-based separation method combined with HPLC was developed to quantify free and liposomal doxorubicin in plasma, showing higher accuracy and sensitivity compared to traditional SPE methods. This approach is suitable for quality assessment and pharmacokinetics evaluation of PEGylated liposomal drugs and other PEGylated nanocarriers.

NANO LETTERS (2021)

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Article Chemistry, Multidisciplinary

Anti-PEG scFv corona ameliorates accelerated blood clearance phenomenon of PEGylated nanomedicines

Zui Zhang et al.

Summary: This study utilized PEG single-chain variable fragment (PEG-scFv) to ameliorate the ABC phenomenon of PEGylated nanomedicines, showing promising results in animal and human experiments. The application of anti-PEG scFv provides a new avenue for improving the performance of PEGylated nanomedicines and mitigating individual differences caused by varying levels of anti-PEG antibodies.

JOURNAL OF CONTROLLED RELEASE (2021)

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Article Chemistry, Analytical

Nanozyme sensor based-on platinum-decorated polymer nanosphere for rapid and sensitive detection of Salmonella typhimurium with the naked eye

Jiao Hu et al.

Summary: A nanozyme Ps-Pt with ultrahigh peroxidase-like catalytic activity was synthesized by growing Pt nanoparticles on the surface of carboxyl functionalized polymer nanospheres; Immune Ps-Pt (IPs-Pt) with higher stability and more antibodies was obtained through a two-step binding method; A simple colorimetric assay based on IPs-Pt showed high sensitivity and 100% accuracy in detecting S. typhi, indicating its feasibility in practical applications.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

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Review Chemistry, Multidisciplinary

Immune Cell Membrane-Coated Biomimetic Nanoparticles for Targeted Cancer Therapy

Fatemeh Oroojalian et al.

Summary: Nanotechnology offers promising opportunities for cancer management, particularly through biomimetic approaches using immune cell membranes to coat nanoparticles for improved stability and targeting; the surface proteins from immune cells can provide various functionalities to nanoparticles, enhancing their efficacy and reducing toxicity.

SMALL (2021)

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Review Chemistry, Physical

Polymer-Based Nanosystems-A Versatile Delivery Approach

Adelina-Gabriela Niculescu et al.

Summary: Polymer-based nanoparticles customized for size, morphology, and surface properties are gaining attention for drug, biomolecule, and gene delivery. They protect payloads from degradation and sustain controlled drug release, reducing clearance and increasing stability, solubility, and optimal concentration at target sites, especially in vaccine development.

MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Rough Carbon-Iron Oxide Nanohybrids for Near-Infrared-II Light-Responsive Synergistic Antibacterial Therapy

Zhiwen Liu et al.

Summary: This study developed carbon-iron oxide nanohybrids with rough surfaces (RCF) for NIR-II light-responsive synergistic antibacterial therapy, showing broad-spectrum synergistic antibacterial effects and satisfactory biocompatibility in vivo.

ACS NANO (2021)

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Review Chemistry, Multidisciplinary

Progress in the Application of Carbon Dots-Based Nanozymes

Jun Jin et al.

Summary: Nanozymes, as functional nanomaterials with enzyme-like properties, have advantages over natural enzymes in terms of stability, cost, design versatility, and applicability. Carbon dots are an ideal choice for composite materials due to their unique physical and chemical properties. Thorough understanding of the working principles, performance evaluation, and application scope of CDs-based nanozymes is crucial for their development in various fields.

FRONTIERS IN CHEMISTRY (2021)

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Review Biochemistry & Molecular Biology

Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance

Magda Ferreira et al.

Summary: Antimicrobial resistance poses a serious public health problem, but encapsulating antibiotics in liposomes can enhance therapeutic effects, reduce drug toxicity, and combat resistant bacteria.

MOLECULES (2021)

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Review Nanoscience & Nanotechnology

Nanotechnology approaches for global infectious diseases

Ameya R. Kirtane et al.

Summary: Infectious diseases pose a significant burden on global health, particularly in the treatment of diseases like malaria, tuberculosis, and HIV. Nanotechnology shows promise in improving treatment outcomes by enhancing drug targeting and patient adherence.

NATURE NANOTECHNOLOGY (2021)

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Article Chemistry, Multidisciplinary

Near-Infrared-Activated Efficient Bacteria-Killing by Lignin-Based Copper Sulfide Nanocomposites with an Enhanced Photothermal Effect and Peroxidase-like Activity

Yuanxiang Xie et al.

Summary: Lignin-copper sulfide (LS-CuS) nanocomposites synthesized using lignosulfonate as a growth template exhibit enhanced photothermal performance and peroxidase-like activity under near-infrared light activation, leading to efficient bacteria-killing through synergistic photothermal-catalytic effects. Moreover, blending LS-CuS nanocomposites with waterborne polyurethane results in hybrid films with over 90% bactericidal efficacy in 5 minutes. The study suggests a sustainable and cost-effective approach to designing lignin-based inorganic nanocomposites with high bacteria-killing efficiency.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2021)

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Article Pharmacology & Pharmacy

The Impact of an Efflux Pump Inhibitor on the Activity of Free and Liposomal Antibiotics against Pseudomonas aeruginosa

Douweh Leyla Gbian et al.

Summary: This study evaluated the efficacy of liposomal gentamicin and erythromycin combined with PABN against P. aeruginosa isolates. The results showed that this combination significantly reduced the minimum inhibitory and bactericidal concentrations, inhibited biofilm formation, and affected virulence factor production and motility of the bacteria to various degrees.

PHARMACEUTICS (2021)

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Article Nanoscience & Nanotechnology

Gold-Platinum Nanodots with High-Peroxidase-like Activity and Photothermal Conversion Efficiency for Antibacterial Therapy

Shengnan Zhang et al.

Summary: The study introduces a simple and fast synthesized gold-platinum nanodots that exhibit broad-spectrum antibacterial properties against bacterial infections and have been shown to promote wound healing in in vivo experiments. These nanodots have good biocompatibility and low toxicity, showing potential as a new option for future antibacterial therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

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Review Pharmacology & Pharmacy

Liposome composition in drug delivery design, synthesis, characterization, and clinical application

Danielle E. Large et al.

Summary: Liposomal drug delivery is a highly adaptable therapeutic platform for treating a wide range of diseases. The molecular diversity in liposome composition enables drug delivery with unique physiological functions, such as pH response and reduced systemic toxicity.

ADVANCED DRUG DELIVERY REVIEWS (2021)

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Article Chemistry, Multidisciplinary

Bamboo-Like Nanozyme Based on Nitrogen-Doped Carbon Nanotubes Encapsulating Cobalt Nanoparticles for Wound Antibacterial Applications

Shaoying He et al.

Summary: An artificial nanozyme N-CNTs@Co with efficient oxidase-mimicking activity was developed in this study, showing a higher activity compared to iron-centered nanomaterials. It can catalyze oxygen to produce reactive oxygen species, leading to a favorable antibacterial effect against Staphylococcus aureus and Escherichia coli. The nanozyme exhibited high antibacterial efficiency without the development of resistance in bacteria and was further confirmed in wound healing experiments in vivo.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Article Chemistry, Multidisciplinary

Bacterial Outer Membrane-Coated Mesoporous Silica Nanoparticles for Targeted Delivery of Antibiotic Rifampicin against Gram-Negative Bacterial Infection In Vivo

Shuang Wu et al.

Summary: This study introduces a biomimetic nanodelivery system consisting of outer membrane vesicles isolated from E. coli as shell and rifampicin-loaded mesoporous silica nanoparticles as core, aiming to enhance bacterial targeting and uptake, thus improving antimicrobial activity against Gram-negative bacteria.

ADVANCED FUNCTIONAL MATERIALS (2021)

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Article Nanoscience & Nanotechnology

Near-Infrared Light Enhanced Peroxidase-Like Activity of PEGylated Palladium Nanozyme for Highly Efficient Biofilm Eradication

Sijin Xiang et al.

Summary: Eradication of biofilm-growing bacteria is crucial for infection control. A PEGylated palladium nanozyme with peroxidase-like activity shows high efficiency in destroying biofilm matrix and killing bacteria. The synergistic treatment based on Pd-PEG+H2O2+NIR combination exhibits outstanding antibacterial effects with low biotoxicity.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2021)

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Article Multidisciplinary Sciences

Glucose-oxidase like catalytic mechanism of noble metal nanozymes

Jinxing Chen et al.

Summary: Gold nanoparticles exhibit enzyme-like activities and can mimic the catalytic process of glucose oxidation enzyme, producing H2O2; other noble metal nanoparticles can also catalyze glucose oxidation reaction, where oxygen is preferably reduced to water.

NATURE COMMUNICATIONS (2021)

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Review Biotechnology & Applied Microbiology

Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol

Pooria Nakhaei et al.

Summary: Liposomes are a type of nanoparticles with a phospholipid membrane, rich in lipid contents, where cholesterol plays a vital role in stability. Despite various applications of liposomes, stability limitations still exist due to ingredient influence.

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2021)

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Review Chemistry, Multidisciplinary

Manganese-based advanced nanoparticles for biomedical applications: future opportunity and challenges

Shagufta Haque et al.

Summary: Nanotechnology, particularly manganese-based nanoparticles, shows great potential in biomedical applications. While there are numerous research reports on manganese nanoparticles, there is a lack of comprehensive review on recent developments and potential applications. This review article surveys the recent advancements in manganese nanomaterials in biomedical fields and discusses future prospects and challenges for wider applications.

NANOSCALE (2021)

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Article Materials Science, Biomaterials

Manganese dioxide nanozyme for reactive oxygen therapy of bacterial infection and wound healing

Li Liu et al.

Summary: The research team has developed a nanozyme that generates reactive oxygen species with high stability and biocompatibility, effectively killing multidrug resistant pathogens, preventing and disrupting biofilm formation, and demonstrating excellent antibacterial performance. This oxidative therapy based nanozyme shows promising potential in treating skin and soft tissue infections in mice.

BIOMATERIALS SCIENCE (2021)

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Review Chemistry, Multidisciplinary

Chemical design principles of next-generation antiviral surface coatings

Nan Wang et al.

Summary: The COVID-19 pandemic has accelerated the development of high-performance antiviral surface coatings and emphasized the importance of understanding the chemical design principles behind them. Cutting-edge advances in material science are being used to engineer antiviral surface coatings that can inhibit membrane-enveloped and non-enveloped viruses. The integration of chemical design principles and advanced material fabrication strategies is leading to next-generation surface coatings that can help prevent viral pandemics and other infectious disease threats.

CHEMICAL SOCIETY REVIEWS (2021)

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Review Nanoscience & Nanotechnology

The age of bioinspired molybdenum-involved nanozymes: Synthesis, catalytic mechanisms, and biomedical applications

Yan Zu et al.

Summary: Bioinspired Mo-based nanozymes, utilizing molybdenum as a transition metal with variable oxidation states, exhibit tunable enzyme-like activity and multifunctionality by regulating their physicochemical properties. These nanomaterials show great potential for biomedical applications with unique structures and physicochemical features.

VIEW (2021)

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Article Chemistry, Analytical

In vitro measurement of superoxide dismutase-like nanozyme activity: a comparative study

Yufeng Liu et al.

Summary: This study evaluated the sensitivity and accuracy of several commonly used in vitro detection methods for SOD-like nanozymes. Different probes have varying sensitivity and suitability for detecting SOD-like nanozymes, and precautions were proposed for each method.

ANALYST (2021)

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Article Chemistry, Multidisciplinary

Gold nanoplates with superb photothermal efficiency and peroxidase-like activity for rapid and synergistic antibacterial therapy

Lu Yan et al.

Summary: Gold nanoplates show high photothermal conversion efficiency and peroxidase-like activity, and when combined with low H2O2 concentration, low AuNPT dosage, and laser irradiation, they exhibit excellent synergistic antibacterial ability and wound healing in vivo.

CHEMICAL COMMUNICATIONS (2021)

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Article Chemistry, Physical

Bienzymatic synergism of vanadium oxide nanodots to efficiently eradicate drug-resistant bacteria during wound healing in vivo

Weishuai Ma et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2020)

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Article Engineering, Biomedical

Encapsulation of collagen mimetic peptide-tethered vancomycin liposomes in collagen-based scaffolds for infection control in wounds

Raj Kumar Thapa et al.

ACTA BIOMATERIALIA (2020)

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Article Chemistry, Physical

Bifunctionalized novel Co-V MMO nanowires: Intrinsic oxidase and peroxidase like catalytic activities for antibacterial application

Yi Wang et al.

APPLIED CATALYSIS B-ENVIRONMENTAL (2020)

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Article Infectious Diseases

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Chih-Cheng Lai et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

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Review Infectious Diseases

Antibiotics targeting bacterial ribosomal subunit biogenesis

W. Scott Champney

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)

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Article Chemistry, Physical

Electrochemical generation of Fe3C/N-doped graphitic carbon nanozyme for efficient wound healing in vivo

Yang Li et al.

CARBON (2020)

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Article Biochemistry & Molecular Biology

Enzyme Mimic Nanomaterials and Their Biomedical Applications

Yingxu Shang et al.

CHEMBIOCHEM (2020)

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Article Biochemistry & Molecular Biology

Bimetallic CuCo2S4 Nanozymes with Enhanced Peroxidase Activity at Neutral pH for Combating Burn Infections

Dandan Li et al.

CHEMBIOCHEM (2020)

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Article Chemistry, Multidisciplinary

A Convenient Colorimetric Bacteria Detection Method Utilizing Chitosan-Coated Magnetic Nanoparticles

Thao Nguyen Le et al.

NANOMATERIALS (2020)

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Article Chemistry, Multidisciplinary

Test-System for Bacteria Sensing Based on Peroxidase-Like Activity of Inkjet-Printed Magnetite Nanoparticles

Maxim Zakharzhevskii et al.

NANOMATERIALS (2020)

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Article Chemistry, Physical

Tuning the ATP-triggered pro-oxidant activity of iron oxide-based nanozyme towards an efficient antibacterial strategy

Nv Srikanth Vallabani et al.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2020)

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Review Medical Laboratory Technology

Topical application of bacteriophages for treatment of wound infections

Rachel Yoon Kyung Chang et al.

TRANSLATIONAL RESEARCH (2020)

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Article Chemistry, Multidisciplinary

Silver nanoparticles-decorated reduced graphene oxide: A novel peroxidase-like activity nanomaterial for development of a colorimetric glucose biosensor

Hoang V. Tran et al.

ARABIAN JOURNAL OF CHEMISTRY (2020)

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Article Pharmacology & Pharmacy

Silver Nanoparticles Coated Poly(L-Lactide) Electrospun Membrane for Implant Associated Infections Prevention

Jiaolong Wang et al.

FRONTIERS IN PHARMACOLOGY (2020)

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Review Chemistry, Multidisciplinary

Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses

Mahmoud Nasrollahzadeh et al.

NANOMATERIALS (2020)

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Review Pharmacology & Pharmacy

Recent advancements in liposome technology

Nina Filipczak et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

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Article Materials Science, Ceramics

Superoxide anion: Critical source of high performance antibacterial activity in Co-Doped ZnO QDs

Junli Liu et al.

CERAMICS INTERNATIONAL (2020)

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Review Pharmacology & Pharmacy

Inhaled Liposomal Antimicrobial Delivery in Lung Infections

Matteo Bassetti et al.

DRUGS (2020)

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Article Chemistry, Multidisciplinary

Iron nanoparticles augmented chemodynamic effect by alternative magnetic field for wound disinfection and healing

Fei Gao et al.

JOURNAL OF CONTROLLED RELEASE (2020)

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Article Engineering, Environmental

Cerium-mediated photooxidation for tuning pH-dependent oxidase-like activity

Shijia Li et al.

CHEMICAL ENGINEERING JOURNAL (2020)

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Article Biochemistry & Molecular Biology

Core-shell Au@Co-Fe hybrid nanoparticles as peroxidase mimetic nanozyme for antibacterial application

Mahboubeh Mirhosseini et al.

PROCESS BIOCHEMISTRY (2020)

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Article Multidisciplinary Sciences

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

Tengfei Liu et al.

NATURE COMMUNICATIONS (2020)

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Article Green & Sustainable Science & Technology

In situ growth of gold and silver nanoparticles onto phyto-functionalized boron nitride nanosheets: Catalytic, peroxidase mimicking, and antimicrobial activity

Aarti R. Deshmukh et al.

JOURNAL OF CLEANER PRODUCTION (2020)

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Article Chemistry, Analytical

Colorimetric immunoassay for rapid detection of Staphylococcus aureus based on etching-enhanced peroxidase-like catalytic activity of gold nanoparticles

Shuo Yao et al.

MICROCHIMICA ACTA (2020)

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Article Chemistry, Multidisciplinary

Highlights in Mesoporous Silica Nanoparticles as a Multifunctional Controlled Drug Delivery Nanoplatform for Infectious Diseases Treatment

Gabriela Correa Carvalho et al.

PHARMACEUTICAL RESEARCH (2020)

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Article Materials Science, Biomaterials

N, S, and P-Co-doped Carbon Quantum Dots: Intrinsic Peroxidase Activity in a Wide pH Range and Its Antibacterial Applications

Kumud Malika Tripathi et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2020)

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Review Biochemistry & Molecular Biology

Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

Natassja G. Bush et al.

MOLECULES (2020)

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Article Materials Science, Multidisciplinary

Peroxidase-like behavior and photothermal effect of chitosan-coated Prussian-blue nanoparticles: dual-modality antibacterial action with enhanced bioaffinity

Nayanika Chakraborty et al.

MATERIALS ADVANCES (2020)

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Article Chemistry, Multidisciplinary

Nanocomposite antimicrobials prevent bacterial growth through the enzyme-like activity of Bi-doped cerium dioxide (Ce1-xBixO2-δ)

Hajo Frerichs et al.

NANOSCALE (2020)

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Review Biophysics

Nanozymes used for antimicrobials and their applications

Dezhi Yang et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

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Article Materials Science, Biomaterials

Oral biofilm elimination by combining iron-based nanozymes and hydrogen peroxide-producing bacteria

Yanqiu Wang et al.

BIOMATERIALS SCIENCE (2020)

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Article Chemistry, Multidisciplinary

ATP fosters the tuning of nanostructured CeO2peroxidase-like activity for promising antibacterial performance

Benazir Chishti et al.

NEW JOURNAL OF CHEMISTRY (2020)

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Article Chemistry, Analytical

Redox Recycling-Triggered Peroxidase-Like Activity Enhancement of Bare Gold Nanoparticles for Ultrasensitive Colorimetric Detection of Rare-Earth Ce3+ Ion

Hao-Hua Deng et al.

ANALYTICAL CHEMISTRY (2019)

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Review Biochemistry & Molecular Biology

Silver Nanoparticles: Synthesis and Application for Nanomedicine

Sang Hun Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

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Article Chemistry, Multidisciplinary

Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

Dandan Luo et al.

JOURNAL OF CONTROLLED RELEASE (2019)

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Article Infectious Diseases

Iron oxide nanoparticles based antiviral activity of H1N1 influenza A virus

Rishikesh Kumar et al.

JOURNAL OF INFECTION AND CHEMOTHERAPY (2019)

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Article Immunology

Clinical Pharmacokinetics, Pharmacodynamics, Safety and Efficacy of Liposomal Amphotericin B

Andreas H. Groll et al.

CLINICAL INFECTIOUS DISEASES (2019)

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Article Chemistry, Multidisciplinary

Manganese as a Catalytic Mediator for Photo-oxidation and Breaking the pH Limitation of Nanozymes

Jinyi Zhang et al.

NANO LETTERS (2019)

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Article Chemistry, Analytical

CuO nanoparticles as haloperoxidase-mimics: Chloride-accelerated heterogeneous Cu-Fenton chemistry for H2O2 and glucose sensing

Li Wang et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

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Article Biotechnology & Applied Microbiology

ARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology

Thomas Ming Swi Chang

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2019)

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Review Chemistry, Multidisciplinary

Nanozymes: From New Concepts, Mechanisms, and Standards to Applications

Minmin Liang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

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Article Engineering, Biomedical

Bioinspired Liposomes for Oral Delivery of Colistin to Combat Intracellular Infections by Salmonella enterica

Sara Menina et al.

ADVANCED HEALTHCARE MATERIALS (2019)

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Article Chemistry, Multidisciplinary

Critical Comparison of the Superoxide Dismutase-like Activity of Carbon Antioxidant Nanozymes by Direct Superoxide Consumption Kinetic Measurements

Gang Wu et al.

ACS NANO (2019)

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Article Oncology

NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act. In. Sarc): a multicentre, phase 2-3, randomised, controlled trial

Sylvie Bonvalot et al.

LANCET ONCOLOGY (2019)

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Review Microbiology

Antibiotics: past, present and future

Matthew I. Hutchings et al.

CURRENT OPINION IN MICROBIOLOGY (2019)

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Article Chemistry, Multidisciplinary

Copper/Carbon Hybrid Nanozyme: Tuning Catalytic Activity by the Copper State for Antibacterial Therapy

Juqun Xi et al.

NANO LETTERS (2019)

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Article Chemistry, Multidisciplinary

Dextran-Coated Iron Oxide Nanoparticles as Biomimetic Catalysts for Localized and pH-Activated Biofilm Disruption

Pratap C. Naha et al.

ACS NANO (2019)

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Article Biochemical Research Methods

Aptamer-mediated colorimetric and electrochemical detection of Pseudomonas aeruginosa utilizing peroxidase-mimic activity of gold NanoZyme

Ritu Das et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2019)

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Article Chemistry, Analytical

Ultrasensitive Colorimetric Detection of Murine Norovirus Using NanoZyme Aptasensor

Pabudi Weerathunge et al.

ANALYTICAL CHEMISTRY (2019)

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Article Biophysics

Highly efficient and selective antimicrobial isonicotinylhydrazide-coated polyoxometalate-functionalized silver nanoparticles

Akhela Umapathi et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2019)

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Article Chemistry, Multidisciplinary

Chiral Molecule-mediated Porous CuxO Nanoparticle Clusters with Antioxidation Activity for Ameliorating Parkinson's Disease

Changlong Hao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

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Article Biotechnology & Applied Microbiology

Biogenic synthesis and effect of silver nanoparticles (AgNPs) to combat catheter-related urinary tract infections

Meera Divya et al.

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY (2019)

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Review Chemistry, Multidisciplinary

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)

Jiangjiexing Wu et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Article Medicine, Research & Experimental

Catalytic inactivation of influenza virus by iron oxide nanozyme

Tao Qin et al.

THERANOSTICS (2019)

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Review Chemistry, Multidisciplinary

Combatting antibiotic-resistant bacteria using nanomaterials

Akash Gupta et al.

CHEMICAL SOCIETY REVIEWS (2019)

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Review Chemistry, Medicinal

Immucillins in Infectious Diseases

Gary B. Evans et al.

ACS INFECTIOUS DISEASES (2018)

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Review Chemistry, Multidisciplinary

Enzyme Mimicry for Combating Bacteria and Biofilms

Zhaowei Chen et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

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Article Nanoscience & Nanotechnology

Nanozymatic Antioxidant System Based on MoS2 Nanosheets

Tongming Chen et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

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Article Chemistry, Multidisciplinary

Protein-Directed Metal Oxide Nanoflakes with Tandem Enzyme-Like Characteristics: Colorimetric Glucose Sensing Based on One-Pot Enzyme-Free Cascade Catalysis

Lei Han et al.

ADVANCED FUNCTIONAL MATERIALS (2018)

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Article Biotechnology & Applied Microbiology

Multifunctional theranostic applications of biocompatible green-synthesized colloidal nanoparticles

Muhammad Ovais et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2018)

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Review Nanoscience & Nanotechnology

Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies

Yun'an Qing et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2018)

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Review Biochemistry & Molecular Biology

Prussian Blue Nanoparticles as a Versatile Photothermal Tool

Giacomo Dacarro et al.

MOLECULES (2018)

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Article Chemistry, Multidisciplinary

Unraveling the Enzymatic Activity of Oxygenated Carbon Nanotubes and Their Application in the Treatment of Bacterial Infections

Huan Wang et al.

NANO LETTERS (2018)

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Article Chemistry, Multidisciplinary

Green synthesis of catalytic gold/bismuth oxyiodide nanocomposites with oxygen vacancies for treatment of bacterial infections

Chia-Lun Hsu et al.

NANOSCALE (2018)

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Article Biochemical Research Methods

Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes

Bing Jiang et al.

NATURE PROTOCOLS (2018)

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Review Polymer Science

Biomimetic antimicrobial polymers: recent advances in molecular design

Cansu Ergene et al.

POLYMER CHEMISTRY (2018)

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Article Chemistry, Multidisciplinary

ROS scavenging Mn3O4 nanozymes for in vivo anti-inflammation

Jia Yao et al.

CHEMICAL SCIENCE (2018)

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Article Multidisciplinary Sciences

Differential Pd-nanocrystal facets demonstrate distinct antibacterial activity against Gram-positive and Gram-negative bacteria

Ge Fang et al.

NATURE COMMUNICATIONS (2018)

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Article Chemistry, Multidisciplinary

Graphene Oxide Quantum Dots Reduce Oxidative Stress and Inhibit Neurotoxicity In Vitro and In Vivo through Catalase-Like Activity and Metabolic Regulation

Chaoxiu Ren et al.

ADVANCED SCIENCE (2018)

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Review Pharmacology & Pharmacy

Application of Nanoparticle Technologies in the Combat against Anti-Microbial Resistance

Mayur Kumar et al.

PHARMACEUTICS (2018)

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Article Critical Care Medicine

Amikacin Liposome Inhalation Suspension for Treatment-Refractory Lung Disease Caused by Mycobacterium avium Complex (CONVERT)

David E. Griffith et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)

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Article Biochemical Research Methods

Mercaptopyrimidine-Conjugated Gold Nanoclusters as Nanoantibiotics for Combating Multidrug-Resistant Superbugs

Youkun Zheng et al.

BIOCONJUGATE CHEMISTRY (2018)

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Article Pharmacology & Pharmacy

Intravenous delivery of a liposomal formulation of voriconazole improves drug pharmacokinetics, tissue distribution, and enhances antifungal activity

Danillo F. M. C. Veloso et al.

DRUG DELIVERY (2018)

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Article Chemistry, Multidisciplinary

Porous Gold Nanoshells on Functional NH2-MOFs: Facile Synthesis and Designable Platforms for Cancer Multiple Therapy

Chuang Liu et al.

SMALL (2018)

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Article Multidisciplinary Sciences

Copper Redox Cycling Inhibits Aβ Fibre Formation and Promotes Fibre Fragmentation, while Generating a Dityrosine Aβ Dimer

Miao Gu et al.

SCIENTIFIC REPORTS (2018)

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Review Engineering, Biomedical

Self-Assembled Nanomedicines for Anticancer and Antibacterial Applications

Lingyun Zhou et al.

ADVANCED HEALTHCARE MATERIALS (2018)

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Article Medicine, General & Internal

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017

Gregory A. Roth et al.

LANCET (2018)

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Article Pharmacology & Pharmacy

Coating Nanoparticles with Gastric Epithelial Cell Membrane for Targeted Antibiotic Delivery against Helicobacter pylori Infection

Pavimol Angsantikul et al.

ADVANCED THERAPEUTICS (2018)

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Article Nanoscience & Nanotechnology

Antifouling Manganese Oxide Nanoparticles: Synthesis, Characterization, and Applications for Enhanced MR Imaging of Tumors

Peng Wang et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

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Review Biochemical Research Methods

Biointerfacing and Applications of Cell Membrane-Coated Nanoparticles

Ashley V. Kroll et al.

BIOCONJUGATE CHEMISTRY (2017)

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Review Nanoscience & Nanotechnology

Effective use of nanocarriers as drug delivery systems for the treatment of selected tumors

Fakhar Ud Din et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)

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Review Pharmacology & Pharmacy

Physicochemical properties of mucus and their impact on transmucosal drug delivery

Jasmim Leal et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)

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Article Chemistry, Analytical

Facile synthesis of iridium nanoparticles with superior peroxidase-like activity for colorimetric determination of H2O2 and xanthine

Malin Cui et al.

SENSORS AND ACTUATORS B-CHEMICAL (2017)

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Review Medicine, Research & Experimental

Iron Oxide Nanozyme: A Multifunctional Enzyme Mimetic for Biomedical Applications

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THERANOSTICS (2017)

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Article Materials Science, Biomaterials

Graphene Quantum Dot/Silver Nanoparticle Hybrids with Oxidase Activities for Antibacterial Application

Shuai Chen et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

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Article Materials Science, Biomaterials

Graphene Quantum Dot/Silver Nanoparticle Hybrids with Oxidase Activities for Antibacterial Application

Shuai Chen et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2017)

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Article Infectious Diseases

Epidemic of Mycoplasma pneumoniae infection in Denmark, 2010 and 2011

S A Uldum et al.

Eurosurveillance (2017)

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Article Chemistry, Multidisciplinary

Fabricating MnO2 Nanozymes as Intracellular Catalytic DNA Circuit Generators for Versatile Imaging of Base-Excision Repair in Living Cells

Feng Chen et al.

ADVANCED FUNCTIONAL MATERIALS (2017)

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Article Nanoscience & Nanotechnology

Single Continuous Near-Infrared Laser-Triggered Photodynamic and Photothermal Ablation of Antibiotic-Resistant Bacteria Using Effective Targeted Copper Sulfide Nanoclusters

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ACS APPLIED MATERIALS & INTERFACES (2017)

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Review Biochemistry & Molecular Biology

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ANNUAL REVIEW OF BIOCHEMISTRY, VOL 86 (2017)

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Review Microbiology

Filamentous Fungal Human Pathogens from Food Emphasising Aspergillus, Fusarium and Mucor

R. Russell M. Paterson et al.

MICROORGANISMS (2017)

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Article Chemistry, Physical

Cobalt nanoparticles for biomedical applications: Facile synthesis, physiochemical characterization, cytotoxicity behavior and biocompatibility

S. M. Ansari et al.

APPLIED SURFACE SCIENCE (2017)

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Article Nanoscience & Nanotechnology

Synergistic antimicrobial therapy using nanoparticles and antibiotics for the treatment of multidrug-resistant bacterial infection

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NANO FUTURES (2017)

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Article Biophysics

ATP-mediated intrinsic peroxidase-like activity of Fe3O4-based nanozyme: One step detection of blood glucose at physiological pH

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COLLOIDS AND SURFACES B-BIOINTERFACES (2017)

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Article Biochemical Research Methods

Fatty Acid Comprising Lysine Conjugates: Anti-MRSA Agents That Display In Vivo Efficacy by Disrupting Biofilms with No Resistance Development

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BIOCONJUGATE CHEMISTRY (2017)

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Article Engineering, Biomedical

Rationally designed dual functional block copolymers for bottlebrush-like coatings: In vitro and in vivo antimicrobial, antibiofilm, and antifouling properties

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ACTA BIOMATERIALIA (2017)

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MICROORGANISMS (2017)

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Pore-forming toxins: ancient, but never really out of fashion

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NATURE REVIEWS MICROBIOLOGY (2016)

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Biomimetic and Bioinspired Synthesis of Nanomaterials/Nanostructures

Guangtao Zan et al.

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Direct electrochemical detection of kanamycin based on peroxidase-like activity of gold nanoparticles

Chunshuai Wang et al.

ANALYTICA CHIMICA ACTA (2016)

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Side Chain Degradable Cationic-Amphiphilic Polymers with Tunable Hydrophobicity Show in Vivo Activity

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Article Biophysics

Sensitive detection of Escherichia coli O157:H7 using Pt-Au bimetal nanoparticles with peroxidase-like amplification

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BIOSENSORS & BIOELECTRONICS (2016)

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Article Biotechnology & Applied Microbiology

Detection of Influenza Virus Using Peroxidase-Mimic of Gold Nanoparticles

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BIOTECHNOLOGY AND BIOENGINEERING (2016)

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Article Biochemistry & Molecular Biology

Transition metal oxide nanoparticles are effective in inhibiting lung cancer cell survival in the hypoxic tumor microenvironment

Namita Pandey et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2016)

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Meeting Abstract Infectious Diseases

Antiviral effect of Glycine coated Iron oxide nanoparticles iron against H1N1 influenza A virus

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INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2016)

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A 980 nm driven photothermal ablation of virulent and antibiotic resistant Gram-positive and Gram-negative bacteria strains using Prussian blue nanoparticles

Houcem Maaoui et al.

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Review Chemistry, Multidisciplinary

Mechanisms of the Antimicrobial Activities of Graphene Materials

Xuefeng Zou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Article Chemistry, Multidisciplinary

Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

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Review Infectious Diseases

Systematic review of antibiotic resistance in acne: an increasing topical and oral threat

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LANCET INFECTIOUS DISEASES (2016)

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Bacterial Hyaluronidase Self-Triggered Prodrug Release for Chemo-Photothermal Synergistic Treatment of Bacterial Infection

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SMALL (2016)

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Article Medicine, Research & Experimental

Aminoglycosides: An Overview

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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

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Lincosamides, Streptogramins, Phenicols, and Pleuromutilins: Mode of Action and Mechanisms of Resistance

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COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)

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Review Chemistry, Inorganic & Nuclear

Nanozymes in bionanotechnology: from sensing to therapeutics and beyond

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INORGANIC CHEMISTRY FRONTIERS (2016)

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Review Pharmacology & Pharmacy

Current Trends in Development of Liposomes for Targeting Bacterial Biofilms

Zora Rukavina et al.

PHARMACEUTICS (2016)

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Review Pharmacology & Pharmacy

Molecular imprinted polymers as drug delivery vehicles

Shabi Abbas Zaidi

DRUG DELIVERY (2016)

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Article Psychology, Clinical

The Negative Side Effects of Vocational Education: A Cross-National Analysis of the Relative Unemployment Risk of Young Non-Western Immigrants in Europe

Bram Lancee

AMERICAN BEHAVIORAL SCIENTIST (2016)

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Article Engineering, Biomedical

Mechanism of pH-switchable peroxidase and catalase-like activities of gold, silver, platinum and palladium

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BIOMATERIALS (2015)

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Article Nanoscience & Nanotechnology

Extracellular Biosynthesis of Copper and Copper Oxide Nanoparticles by Stereum hirsutum, a Native White-Rot Fungus from Chilean Forests

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Article Nanoscience & Nanotechnology

Colorimetric Detection System for Salmonella typhimurium Based on Peroxidase-Like Activity of Magnetic Nanoparticles with DNA Aptamers

Ji Young Park et al.

JOURNAL OF NANOMATERIALS (2015)

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Article Chemistry, Multidisciplinary

Mechanisms of Oxidase and Superoxide Dismutation-like Activities of Gold, Silver, Platinum, and Palladium, and Their Alloys: A General Way to the Activation of Molecular Oxygen

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

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Modulating Antibacterial Immunity via Bacterial Membrane-Coated Nanoparticles

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NANO LETTERS (2015)

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Article Engineering, Biomedical

Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug-Resistant MRSA Systemic Infection

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ADVANCED HEALTHCARE MATERIALS (2015)

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Article Biotechnology & Applied Microbiology

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

Brian D. Henry et al.

NATURE BIOTECHNOLOGY (2015)

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Review Microbiology

Molecular mechanisms of antibiotic resistance

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NATURE REVIEWS MICROBIOLOGY (2015)

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Core-Shell Supramolecular Gelatin Nanoparticles for Adaptive and On-Demand Antibiotic Delivery

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ACS NANO (2014)

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Graphene Quantum Dots-Band-Aids Used for Wound Disinfection

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Molybdenum Trioxide Nanoparticles with Intrinsic Sulfite Oxidase Activity

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ACS NANO (2014)

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Article Biochemistry & Molecular Biology

Cationic Methacrylate Polymers as Topical Antimicrobial Agents against Staphylococcus aureus Nasal Colonization

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BIOMACROMOLECULES (2014)

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Review Biochemical Research Methods

Caged protein nanoparticles for drug delivery

Nicholas M. Molino et al.

CURRENT OPINION IN BIOTECHNOLOGY (2014)

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State-of-the-art in design rules for drug delivery platforms: Lessons learned from FDA-approved nanomedicines

Charlene M. Dawidczyk et al.

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Article Chemistry, Physical

Ceria-supported copper nanoparticles: A highly efficient and recyclable catalyst for N-arylation of indole

Othmane Amadine et al.

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL (2014)

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Article Chemistry, Multidisciplinary

Polyacrylic Acid-Coated Iron Oxide Nanoparticles for Targeting Drug Resistance in Mycobacteria

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LANGMUIR (2014)

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Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

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NANO LETTERS (2014)

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Review Biotechnology & Applied Microbiology

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

Vladimir P. Torchilin

NATURE REVIEWS DRUG DISCOVERY (2014)

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Review Biotechnology & Applied Microbiology

Ligand-targeted liposome design: challenges and fundamental considerations

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TRENDS IN BIOTECHNOLOGY (2014)

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An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

Amit A. Vernekar et al.

NATURE COMMUNICATIONS (2014)

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Inhaled liposomal amikacin

Valerie Waters et al.

EXPERT REVIEW OF RESPIRATORY MEDICINE (2014)

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Review Pharmacology & Pharmacy

Nanotechnology as a therapeutic tool to combat microbial resistance

Robert Y. Pelgrift et al.

ADVANCED DRUG DELIVERY REVIEWS (2013)

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Activation of H2O2 and superoxide production using a novel cobalt complex based on a polyampholyte

Lucia V. Lombardo Lupano et al.

APPLIED CATALYSIS A-GENERAL (2013)

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Intrinsic catalytic activity of Au nanoparticles with respect to hydrogen peroxide decomposition and superoxide scavenging

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BIOMATERIALS (2013)

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A universal strategy for the hierarchical assembly of functional 0/2D nanohybrids

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Aerobic Copper-Catalyzed Organic Reactions

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CHEMICAL REVIEWS (2013)

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Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

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CHEMICAL SOCIETY REVIEWS (2013)

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Review Food Science & Technology

Antibiotic-Resistant Bacteria: A Challenge for the Food Industry

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CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2013)

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Review Chemistry, Multidisciplinary

Composite magnetic-plasmonic nanoparticles for biomedicine: Manipulation and imaging

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NANO TODAY (2013)

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Review Microbiology

Antimicrobial activity of metals: mechanisms, molecular targets and applications

Joseph A. Lemire et al.

NATURE REVIEWS MICROBIOLOGY (2013)

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Review Microbiology

Role of Pore-Forming Toxins in Bacterial Infectious Diseases

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MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2013)

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Review Microbiology

Beta-lactamase induction and cell wall metabolism in Gram-negative bacteria

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FRONTIERS IN MICROBIOLOGY (2013)

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Article Chemistry, Multidisciplinary

Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity

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Mechanisms of the pH dependent generation of hydroxyl radicals and oxygen induced by Ag nanoparticles

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BIOMATERIALS (2012)

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Review Chemistry, Multidisciplinary

Copper Nanoparticle-Catalyzed Carbon?Carbon and Carbon?Heteroatom Bond Formation with a Greener Perspective

Brindaban C. Ranu et al.

CHEMSUSCHEM (2012)

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Review Microbiology

Predictors of Mortality in Staphylococcus aureus Bacteremia

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CLINICAL MICROBIOLOGY REVIEWS (2012)

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Article Neurosciences

Nanoparticle Delivery of Transition-Metal Chelators to the Brain: Oxidative Stress will Never See it Coming!

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CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2012)

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Review Chemistry, Multidisciplinary

Doxil® - The first FDA-approved nano-drug: Lessons learned

Yechezkel (Chezy) Barenholz

JOURNAL OF CONTROLLED RELEASE (2012)

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Article Chemistry, Multidisciplinary

Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

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Article Nanoscience & Nanotechnology

Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation

Filipe Natalio et al.

NATURE NANOTECHNOLOGY (2012)

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Analytical and environmental applications of nanoparticles as enzyme mimetics

Jianxin Xie et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2012)

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Review Biotechnology & Applied Microbiology

Antibacterial properties of nanoparticles

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TRENDS IN BIOTECHNOLOGY (2012)

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Biosynthesis of Au nanoparticles using olive leaf extract

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ARABIAN JOURNAL OF CHEMISTRY (2012)

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Review Immunology

The potential of nitric oxide releasing therapies as antimicrobial agents

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VIRULENCE (2012)

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Review Pharmacology & Pharmacy

Novel classes of antibiotics or more of the same?

Anthony R. M. Coates et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

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Article Infectious Diseases

Resistance class 1 integron in clinical methicillin-resistant Staphylococcus aureus strains in southern China, 2001-2006

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CLINICAL MICROBIOLOGY AND INFECTION (2011)

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Article Chemistry, Physical

Peroxidase-like catalytic activity of cubic Pt nanocrystals

Ming Ma et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2011)

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Article Chemistry, Physical

Silver Nanoparticle-Reactive Oxygen Species Interactions: Application of a Charging-Discharging Model

Di He et al.

JOURNAL OF PHYSICAL CHEMISTRY C (2011)

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Article Chemistry, Multidisciplinary

Bacterial Toxin-Triggered Drug Release from Gold Nanoparticle-Stabilized Liposomes for the Treatment of Bacterial Infection

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Article Chemistry, Multidisciplinary

Amine-Assisted Synthesis of Concave Polyhedral Platinum Nanocrystals Having {411} High-Index Facets

Xiaoqing Huang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

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Erythrocyte membrane-camouflaged polymeric nanoparticles as a biomimetic delivery platform

Che-Ming J. Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Susceptibility of Gram-positive and -negative bacteria to novel nitric oxide-releasing nanoparticle technology

Adam Friedman et al.

VIRULENCE (2011)

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Review Chemistry, Multidisciplinary

De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

Gregory N. Tew et al.

ACCOUNTS OF CHEMICAL RESEARCH (2010)

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Article Biochemistry & Molecular Biology

Study of the Multidrug Membrane Transporter of Single Living Pseudomonas aeruginosa Cells Using Size-Dependent Plasmonic Nanoparticle Optical Probes

Prakash D. Nallathamby et al.

BIOCHEMISTRY (2010)

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Article Chemistry, Multidisciplinary

Nanoceria exhibit redox state-dependent catalase mimetic activity

Talib Pirmohamed et al.

CHEMICAL COMMUNICATIONS (2010)

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Molecular implications in the nanoencapsulation of the anti-tuberculosis drug rifampicin within flower-like polymeric micelles

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COLLOIDS AND SURFACES B-BIOINTERFACES (2010)

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Article Infectious Diseases

Encapsulation in fusogenic liposomes broadens the spectrum of action of vancomycin against Gram-negative bacteria

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INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2010)

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Article Chemistry, Medicinal

Structure-Activity Relationships of Polymyxin Antibiotics

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JOURNAL OF MEDICINAL CHEMISTRY (2010)

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Review Nanoscience & Nanotechnology

Nanodelivery in airway diseases: Challenges and therapeutic applications

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NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2010)

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Review Microbiology

A brief history of the antibiotic era: lessons learned and challenges for the future

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FRONTIERS IN MICROBIOLOGY (2010)

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The Global Problem of Antibiotic Resistance

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CRITICAL REVIEWS IN IMMUNOLOGY (2010)

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Redefining Chronic Viral Infection

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CELL (2009)

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Review Infectious Diseases

Colistin in the 21st century

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CURRENT OPINION IN INFECTIOUS DISEASES (2009)

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Review Pathology

Nanoparticle-based targeted drug delivery

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EXPERIMENTAL AND MOLECULAR PATHOLOGY (2009)

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Tuning selectivity in catalysis by controlling particle shape

Ilkeun Lee et al.

NATURE MATERIALS (2009)

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Article Chemistry, Inorganic & Nuclear

Synthesis, structure, and catalase-like activity of a novel manganese(II) complex: Dichloro[ 1,3-bis(2′-benzimidazolylimino)isoindoline]manganese(II)

Jozsef Kaizer et al.

POLYHEDRON (2009)

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Review Cell Biology

Human skin wounds: A major and snowballing threat to public health and the economy

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WOUND REPAIR AND REGENERATION (2009)

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Article Biochemistry & Molecular Biology

SOD-like activity of Mn(II) β-octabromo-meso-tetrakis(N-methylpyridinium-3-yl)-porphyrin equals that of the enzyme itself

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ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2008)

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The role of cerium redox state in the SOD mimetic activity of nanoceria

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BIOMATERIALS (2008)

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Review Nanoscience & Nanotechnology

Drug delivery and nanoparticles: Applications and hazards

Wim H. De Jong et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2008)

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Review Pharmacology & Pharmacy

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

Tatsuhiro Ishida et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)

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Article Infectious Diseases

Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections

P. Meers et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2008)

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Article Chemistry, Multidisciplinary

Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats

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JOURNAL OF CONTROLLED RELEASE (2008)

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Review Plant Sciences

Synergism between natural products and antibiotics against infectious diseases

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PHYTOMEDICINE (2008)

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Review Immunology

Antifungal immunotherapy and immunomodulation: A double-hitter approach to deal with invasive fungal infections

M. Hamad

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2008)

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Article Nanoscience & Nanotechnology

Synthesis and effect of silver nanoparticles on the antibacterial activity of different antibiotics against Staphylococcus aureus and Escherichia coli

Ahmad R. Shahverdi et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2007)

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Article Chemistry, Medicinal

In vitro antimicrobial activity of liposomes containing ciprofloxacin, meropenem and gentamicin against gram-negative clinical bacterial strains

Jerzy Gubernator et al.

LETTERS IN DRUG DESIGN & DISCOVERY (2007)

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Article Chemistry, Medicinal

Topical delivery of silver nanoparticles promotes wound healing

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CHEMMEDCHEM (2007)

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Review Infectious Diseases

The molecular evolution of methicillin-resistant Staphylococcus aureus

R. H. Deurenberg et al.

CLINICAL MICROBIOLOGY AND INFECTION (2007)

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Review Biotechnology & Applied Microbiology

New-concept chemotherapy by nanoparticles of biodegradable polymers: where are we now?

Si-Shen Feng

NANOMEDICINE (2006)

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Article Chemistry, Multidisciplinary

PEG-modified gold nanorods with a stealth character for in vivo applications

Takuro Niidome et al.

JOURNAL OF CONTROLLED RELEASE (2006)

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Article Multidisciplinary Sciences

General strategies for nanoparticle dispersion

ME Mackay et al.

SCIENCE (2006)

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Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

T Yamase

JOURNAL OF MATERIALS CHEMISTRY (2005)

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Article Oncology

Complete tumor response following intratumoral 32P BioSilicon on human hepatocellular and pancreatic carcinoma xenografts in nude mice

K Zhang et al.

CLINICAL CANCER RESEARCH (2005)

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Article Biotechnology & Applied Microbiology

Development of a rapid immunochromatographic strip for detection of Escherichia coli O157

BY Jung et al.

JOURNAL OF FOOD PROTECTION (2005)

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Article Oncology

Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer

JF Kukowska-Latallo et al.

CANCER RESEARCH (2005)

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Review Public, Environmental & Occupational Health

Bacterial resistance to silver in wound care

SL Percival et al.

JOURNAL OF HOSPITAL INFECTION (2005)

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Article Infectious Diseases

A case-control study for multidrug-resistant tuberculosis:: Risk factors in four European countries

M Casal et al.

MICROBIAL DRUG RESISTANCE (2005)

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Article Chemistry, Multidisciplinary

Superoxide dismutase-like activity of cobalt(II) complexes based on a sugar platform

F Bellot et al.

CHEMICAL COMMUNICATIONS (2005)

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Article Chemistry, Multidisciplinary

Helical peptoid mimics of magainin-2 amide

JA Patch et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)

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Review Microbiology

Persistence of antibiotic resistant bacteria

DI Andersson

CURRENT OPINION IN MICROBIOLOGY (2003)

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Article Multidisciplinary Sciences

Redefining cholesterol's role in the mechanism of the cholesterol's-dependent cytolysins

KS Giddings et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

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Review Microbiology

Bacterial silver resistance: molecular biology and uses and misuses of silver compounds

S Silver

FEMS MICROBIOLOGY REVIEWS (2003)

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Review Infectious Diseases

Antibiotic efflux pumps in prokaryotic cells:: occurrence, impact on resistance and strategies for the future of antimicrobial therapy

F Van Bambeke et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2003)

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Review Pharmacology & Pharmacy

Voriconazole

L Jeu et al.

CLINICAL THERAPEUTICS (2003)

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Review Immunology

Voriconazole: A new triazole antifungal agent

LB Johnson et al.

CLINICAL INFECTIOUS DISEASES (2003)

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Review Immunology

Bacterial resistance: Origins, epidemiology, and impact

DM Livermore

CLINICAL INFECTIOUS DISEASES (2003)

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Review Microbiology

Resistance mechanisms of Gram-positive bacteria

B Berger-Bächi

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2002)

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Article Chemistry, Inorganic & Nuclear

A dinuclear manganese(II) complex with the {Mn2(μ-O2CCH3)3}+ core:: Synthesis, structure, characterization, electroinduced transformation, and catalase-like activity

I Romero et al.

INORGANIC CHEMISTRY (2002)

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Article Chemistry, Inorganic & Nuclear

Synthesis, characterization and SOD-like activities of manganese-containing complexes with N,N,N′,N′-tetrakis(2′-benzimidazolyl methyl)-1,2-ethanediamine (EDTB)

ZR Liao et al.

POLYHEDRON (2001)

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Review Infectious Diseases

The problem with cephalosporins

SJ Dancer

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2001)

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Article Immunology

Antibiotic resistance: Consequences of inaction

SB Levy

CLINICAL INFECTIOUS DISEASES (2001)

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Article Immunology

The changing epidemiology of Staphylococcus aureus?

HF Chambers

EMERGING INFECTIOUS DISEASES (2001)

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Review Immunology

Epidemiology and pathogenesis of Neisseria meningitidis

YL Tzeng et al.

MICROBES AND INFECTION (2000)

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Article Biochemistry & Molecular Biology

Demonstration of a fusion mechanism between a fluid bactericidal liposomal formulation and bacterial cells

S Sachetelli et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)

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Review Pharmacology & Pharmacy

Tuftsin-bearing liposomes in treatment of macrophage-based infections

AK Agrawal et al.

ADVANCED DRUG DELIVERY REVIEWS (2000)

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