期刊
NUTRIENTS
卷 15, 期 22, 页码 -出版社
MDPI
DOI: 10.3390/nu15224763
关键词
low-carbohydrate diet; low-fat diet; metabolic-dysfunction-associated fatty liver disease; severe fibrosis; quality of macronutrients
This study found that healthy low-carbohydrate diet (LCD) and low-fat diet (LFD) can protect against metabolic-dysfunction-associated fatty liver disease (MAFLD), while unhealthy LFD can increase the risk of MAFLD. Both the quantity and quality of macronutrients have significant influences on MAFLD.
Background: This observational cross-sectional study was designed to explore the effects of a low-carbohydrate diet (LCD) and a low-fat diet (LFD) on metabolic-dysfunction-associated fatty liver disease (MAFLD). Methods: This study involved 3961 adults. The associations between LCD/LFD scores and MAFLD were evaluated utilizing a multivariable logistic regression model. Additionally, a leave-one-out model was applied to assess the effect of isocaloric substitution of specific macronutrients. Results: Participants within the highest tertile of healthy LCD scores (0.63; 95% confidence interval [CI], 0.45-0.89) or with a healthy LFD score (0.64; 95%CI, 0.48-0.86) faced a lower MAFLD risk. Furthermore, compared with tertile 1, individuals with unhealthy LFD scores in terile 2 or tertile 3 had 49% (95%CI, 1.17-1.90) and 77% (95%CI, 1.19-2.63) higher risk levels for MAFLD, respectively. Conclusions: Healthy LCD and healthy LFD are protective against MAFLD, while unhealthy LFD can increase the risk of MAFLD. Both the quantity and quality of macronutrients might have significant influences on MAFLD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据