4.6 Article

The Management of Data for the Banking, Qualification, and Distribution of Induced Pluripotent Stem Cells: Lessons Learned from the European Bank for Induced Pluripotent Stem Cells

期刊

CELLS
卷 12, 期 23, 页码 -

出版社

MDPI
DOI: 10.3390/cells12232756

关键词

stem cell data; standardization; data management; FAIRness

向作者/读者索取更多资源

The European Bank for induced pluripotent Stem Cells (EBiSC) is a non-profit project that aims to provide storage, quality control, and distribution services for human iPSCs for research worldwide. Through collaboration with the human pluripotent stem cell registry (hPSCreg®), EBiSC has successfully standardized the management of cell lines and associated data, providing a model for other iPSC repositories to enhance the FAIRness of iPSC research globally.
The European Bank for induced pluripotent Stem Cells (EBiSC) was established in 2014 as a non-profit project for the banking, quality control, and distribution of human iPSC lines for research around the world. EBiSC iPSCs are deposited from diverse laboratories internationally and, hence, a key activity for EBiSC is standardising not only the iPSC lines themselves but also the data associated with them. This includes enabling unique nomenclature for the cells, as well as applying uniformity to the data provided by the cell line generator versus quality control data generated by EBiSC, and providing mechanisms to share personal data in a secure and GDPR-compliant manner. A joint approach implemented by EBiSC and the human pluripotent stem cell registry (hPSCreg (R)) has provided a solution that enabled hPSCreg (R) to improve its registration platform for iPSCs and EBiSC to have a pipeline for the import, standardisation, storage, and management of data associated with EBiSC iPSCs. In this work, we describe the experience of cell line data management for iPSC banking throughout the course of EBiSC's development as a central European banking infrastructure and present a model for how this could be implemented by other iPSC repositories to increase the FAIRness of iPSC research globally.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据