☆ 4.6 Review

Potential Crosstalk between the PACAP/VIP Neuropeptide System and Endoplasmic Reticulum Stress-Relevance to Multiple Sclerosis Pathophysiology

CELLS (2023)

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Multiple Sclerosis: Pathogenesis and Treatment

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CURRENT NEUROPHARMACOLOGY (2011)

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Review Pharmacology & Pharmacy

Protective Effects of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Against Apoptosis

Tommy Seaborn et al.

CURRENT PHARMACEUTICAL DESIGN (2011)

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Article Biochemistry & Molecular Biology

Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer's disease-like pathology in amyloid precursor protein-transgenic mice

Dorothea Rat et al.

FASEB JOURNAL (2011)

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Article Clinical Neurology

Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis

Paula Cunnea et al.

MULTIPLE SCLEROSIS JOURNAL (2011)

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Article Public, Environmental & Occupational Health

Sun Exposure, Vitamin D and Age at Disease Onset in Relapsing Multiple Sclerosis

Tzu-Yun McDowell et al.

NEUROEPIDEMIOLOGY (2011)

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Article Biochemistry & Molecular Biology

Regulation of Oxidative Stress by Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Mediated by PACAP Receptor

Hirokazu Ohtaki et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2010)

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Review Immunology

ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

Antero Salminen et al.

JOURNAL OF NEUROINFLAMMATION (2009)

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Review Neurosciences

Endoplasmic reticulum stress in disorders of myelinating cells

Wensheng Lin et al.

NATURE NEUROSCIENCE (2009)

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Article Pharmacology & Pharmacy

Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

D. Vaudry et al.

PHARMACOLOGICAL REVIEWS (2009)

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Review Pathology

Endoplasmic reticulum stress in disease pathogenesis

Jonathan H. Lin et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)

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Elevated activity and microglial expression of myeloperoxidase in demyelinated cerebral cortex in multiple sclerosis

Elizabeth Gray et al.

BRAIN PATHOLOGY (2008)

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PACAP and VIP prevent apoptosis in schwannoma cells

Alessandro Castorina et al.

BRAIN RESEARCH (2008)

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Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing

Kenneth P. K. Lee et al.

CELL (2008)

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Article Biochemistry & Molecular Biology

Implication of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) for Neuroprotection of Nicotinic Acetylcholine Receptor Signaling in PC12 Cells

Aiko Tominaga et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2008)

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Article Biochemistry & Molecular Biology

Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) and Vasoactive Intestinal Peptide (VIP) Regulate Murine Neural Progenitor Cell Survival, Proliferation, and Differentiation

Eugene Scharf et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2008)

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Article Clinical Neurology

Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions

Aoife Ni Mhaille et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)

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Inhibition of oligodendrocyte precursor cell differentiation by myelin-associated proteins

Yasir A. Syed et al.

NEUROSURGICAL FOCUS (2008)

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Endoplasmic reticulum stress-induced apoptosis requires bax for commitment and Apaf-1 for execution in primary neurons

M. I. Smith et al.

CELL DEATH AND DIFFERENTIATION (2007)

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Article Medicine, Research & Experimental

The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

Wensheng Lin et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

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Article Immunology

The neuropeptide genes TAC1, TAC3, TAC4, VIP and PACAP (ADCYAP1), and susceptibility to multiple sclerosis

Stephen Cunningham et al.

JOURNAL OF NEUROIMMUNOLOGY (2007)

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Article Pharmacology & Pharmacy

Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: Potent regulators of microglia-mediated oxidative stress

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Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

MR Kotter et al.

JOURNAL OF NEUROSCIENCE (2006)

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Review Pharmacology & Pharmacy

Dual effects of antioxidants in neurodegeneration: Direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation

Jia-Yi Wang et al.

CURRENT PHARMACEUTICAL DESIGN (2006)

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Article Cell Biology

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

WS Lin et al.

JOURNAL OF CELL BIOLOGY (2005)

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Article Neurosciences

Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain

KM Joo et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2004)

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Review Clinical Neurology

Signaling cascades regulating NMDA receptor sensitivity to ethanol

D Ron

NEUROSCIENTIST (2004)

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Article Neurosciences

Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2α in the central nervous system of SJL mice with experimental allergic encephalomyelitis

A Chakrabarty et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2004)

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Article Clinical Neurology

Pituitary adenylate cyclase-activating polypeptide (PACAP) ameliorates experimental autoimmune encephalomyelitis by suppressing the functions of antigen presenting cells

H Kato et al.

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Increased expression of vasoactive intestinal polypeptide in cultured myenteric neurons from adult rat small intestine

Z Lin et al.

AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2003)

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Article Cell Biology

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit the production of inflammatory mediators by activated microglia

M Delgado et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2003)

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Review Neurosciences

Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's disease

MP Mattson

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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals

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DEVELOPMENTAL CELL (2002)

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Pathogenesis of multiple sclerosis: an update on immunology

B Hemmer et al.

CURRENT OPINION IN NEUROLOGY (2002)

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

C Lock et al.

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Pituitary adenylyl cyclase-activating polypeptide stimulates DNA synthesis but delays maturation of oligodendrocyte progenitors

M Lee et al.

JOURNAL OF NEUROSCIENCE (2001)

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

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NATURE CELL BIOLOGY (2000)

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