Underwater clip closure method for mucosal defects after duodenal endoscopic submucosal dissection (with video)

Article Gastroenterology & Hepatology

Clinical course and management of adverse events after endoscopic resection of superficial duodenal epithelial tumors: Multicenter retrospective study

Osamu Dohi et al.

Summary: This study aimed to clarify the clinical course and management of adverse events (AEs) after endoscopic resection (ER) for superficial duodenal epithelial tumors (SDETs). The results showed that delayed perforation had a higher surgical conversion rate compared to other AEs, and involvement of the major papilla and delayed perforation were significant risk factors for surgical conversion after AEs.

DIGESTIVE ENDOSCOPY (2023)

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Article Gastroenterology & Hepatology

Outcomes of endoscopic resection for superficial duodenal tumors: 10 years' experience in 18 Japanese high volume centers

Motohiko Kato et al.

Summary: Background data on endoscopic resection for superficial duodenal epithelial tumors are limited due to their rarity. Different techniques such as EMR and ESD have varying success rates and complications. ESD may be a good option for large SDETs, especially when performed by experienced endoscopists.

ENDOSCOPY (2022)

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Review Gastroenterology & Hepatology

Recent approach for preventing complications in upper gastrointestinal endoscopic submucosal dissection

Waku Hatta et al.

Summary: This article introduces the methods and techniques for preventing complications during upper gastrointestinal endoscopic submucosal dissection (ESD). In esophageal and gastric ESD, intraoperative perforation is a major complication that can be prevented by avoiding blind dissection and using traction-assisted ESD. Delayed bleeding is the most common complication in gastric ESD, and a prediction model (BEST-J score) has been established to assess the risk of delayed bleeding. Vonoprazan >= 20 mg/day is currently the only reliable method for reducing delayed bleeding in gastric ESD. Duodenal ESD has a higher frequency of complications, such as perforation and delayed bleeding, but advancements in devices and techniques have decreased the occurrence. Several ESD techniques, including the use of the distal tips of the Clutch Cutter, can help prevent intraoperative perforation. Standardization of duodenal ESD and further studies are still needed.

DEN OPEN (2022)

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Review Gastroenterology & Hepatology

Efficacy of endoscopic preventive procedures to reduce delayed adverse events after endoscopic resection of superficial nonampullary duodenal epithelial tumors: a meta-analysis of observational comparative trials

Koshiro Tsutsumi et al.

Summary: This study found that preventive procedures, including mucosal sutures and coverage of mucosal defects, significantly reduced the risk of delayed adverse events by more than 80% after endoscopic resection of the duodenum.

GASTROINTESTINAL ENDOSCOPY (2021)

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Article Gastroenterology & Hepatology

Predictors of technical difficulty for complete closure of mucosal defects after duodenal endoscopic resection

Mari Mizutani et al.

Summary: This study revealed that lesion location in the medial or anterior wall and lesion size affected the incomplete closure of mucosal defects after duodenal ER, and lesion size, occupied circumference, intraoperative perforation, treatment period, and treatment method affected closure time.

GASTROINTESTINAL ENDOSCOPY (2021)

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Article Gastroenterology & Hepatology