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Raster image cross-correlation analysis for spatiotemporal visualization of intracellular degradation activities against exogenous DNAs
Akira Sasaki et al.
SCIENTIFIC REPORTS (2015)
Novel High-Throughput Deoxyribonuclease 1 Assay
Dae Song Jang et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
DNA studies using atomic force microscopy: capabilities for measurement of short DNA fragments
Dalong Pang et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2015)
HPLC for Separation and Quantification of Deoxyribonucleic Acid Fragments and Measurement of Deoxyribonucleic Acid Degradation
Sachie Shibayama et al.
CHROMATOGRAPHIA (2014)
Recent applications of fluorescence correlation spectroscopy in live systems
Radek Machan et al.
FEBS LETTERS (2014)
Quantification of cytosolic plasmid DNA degradation using high-throughput sequencing: implications for gene delivery
Rahul Rattan et al.
JOURNAL OF GENE MEDICINE (2014)
mRNA stability in the nucleus
Han Liu et al.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2014)
TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End Modifications
Hyeshik Chang et al.
MOLECULAR CELL (2014)
A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines
Luis A. Brito et al.
MOLECULAR THERAPY (2014)
Non-viral vectors for gene-based therapy
Hao Yin et al.
NATURE REVIEWS GENETICS (2014)
Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B
A. C. Nathwani et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages
W. Brad Wan et al.
NUCLEIC ACIDS RESEARCH (2014)
Atomic force microscopy study of DNA flexibility on short length scales: smooth bending versus kinking
Alexey K. Mazur et al.
NUCLEIC ACIDS RESEARCH (2014)
The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification
Karolina A. Majorek et al.
NUCLEIC ACIDS RESEARCH (2014)
Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice
Thazha P. Prakash et al.
NUCLEIC ACIDS RESEARCH (2014)
DENATURING REVERSED-PHASE HPLC USING A MOBILE PHASE CONTAINING UREA FOR OLIGODEOXYNUCLEOTIDE ANALYSIS
Suntara Fueangfung et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2014)
Electroporation and Microinjection Successfully Deliver Single-Stranded and Duplex DNA into Live Cells as Detected by FRET Measurements
Rosemary A. Bamford et al.
PLOS ONE (2014)
Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
Thomas S. Ligon et al.
PLOS ONE (2014)
Probing the inherent stability of siRNA immobilized on nanoparticle constructs
Stacey N. Barnaby et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Ribonuclease III mechanisms of double-stranded RNA cleavage
Allen W. Nicholson
WILEY INTERDISCIPLINARY REVIEWS-RNA (2014)
Synthesis and Gene Silencing Properties of siRNAs Containing Terminal Amide Linkages
Maria Gaglione et al.
BIOMED RESEARCH INTERNATIONAL (2014)
RNase III: Genetics and Function; Structure and Mechanism
Donald L. Court et al.
ANNUAL REVIEW OF GENETICS, VOL 47 (2013)
Stability, resolution, and ultra-low wear amplitude modulation atomic force microscopy of DNA: Small amplitude small set-point imaging
Sergio Santos et al.
APPLIED PHYSICS LETTERS (2013)
Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B
Stanley T. Crooke et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Multiplex Picoliter-Droplet Digital PCR for Quantitative Assessment of DNA Integrity in Clinical Samples
Audrey Didelot et al.
CLINICAL CHEMISTRY (2013)
The mammalian secreted RNases: Mechanisms of action in host defence
Sandeep K. Gupta et al.
INNATE IMMUNITY (2013)
Evaluation of carrier-mediated siRNA delivery: Lessons for the design of a stem-loop qPCR-based approach for quantification of intracellular full-length siRNA
Stefano Colombo et al.
JOURNAL OF CONTROLLED RELEASE (2013)
Reversed-phase ion-pair liquid chromatography method for purification of duplex DNA with single base pair resolution
Christina L. Wysoczynski et al.
NUCLEIC ACIDS RESEARCH (2013)
Peptide-LNA oligonucleotide conjugates
I. Kira Astakhova et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2013)
Visualizing the Attack of RNase Enzymes on Dendriplexes and Naked RNA Using Atomic Force Microscopy
Hosam G. Abdelhady et al.
PLOS ONE (2013)
Chromatin Accessibility Data Sets Show Bias Due to Sequence Specificity of the DNase I Enzyme
Hashem Koohy et al.
PLOS ONE (2013)
Mutant KRAS is a druggable target for pancreatic cancer
Elina Zorde Khvalevsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The intimate relationships of mRNA decay and translation
Bijoyita Roy et al.
TRENDS IN GENETICS (2013)
SiRNAs conjugated with aromatic compounds induce RISC-mediated antisense strand selection and strong gene-silencing activity
Takanori Kubo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Mechanisms and emerging functions of DNA degradation in the epidermis
Leopold Eckhart et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2012)
The regulation of mRNA stability in mammalian cells: 2.0
Xiangyue Wu et al.
GENE (2012)
Expression, purification and characterization of the interferon-inducible, antiviral and tumour-suppressor protein, human RNase L
Ankush Gupta et al.
JOURNAL OF BIOSCIENCES (2012)
Determination of RNA degradation by capillary electrophoresis with cyan light-emitted diode-induced fluorescence
Tzu-Hsueh Yang et al.
JOURNAL OF CHROMATOGRAPHY A (2012)
In Posidonia oceanica cadmium induces changes in DNA methylation and chromatin patterning
Maria Greco et al.
JOURNAL OF EXPERIMENTAL BOTANY (2012)
Synthesis, Gene Silencing, and Molecular Modeling Studies of 4′-C-Aminomethyl-2′-O-methyl Modified Small Interfering RNAs
Kiran R. Gore et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Application of a ultra performance liquid chromatography method in the determination of DNA quality and stability
Jamie Betker et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
A simple high performance liquid chromatography method for the measurement of nucleobases and the RNA and DNA content of cellular material
Qinghui Huang et al.
LIMNOLOGY AND OCEANOGRAPHY-METHODS (2012)
DNase-activatable fluorescence probes visualizing the degradation of exogenous DNA in living cells
Ping Gong et al.
NANOSCALE (2012)
Glybera and the future of gene therapy in the European Union
Norman Miller
NATURE REVIEWS DRUG DISCOVERY (2012)
Structure and activity of the only human RNase T2
Andrea Thorn et al.
NUCLEIC ACIDS RESEARCH (2012)
Fluorogenic RNA Nanoparticles for Monitoring RNA Folding and Degradation in Real Time in Living Cells
Randall Reif et al.
NUCLEIC ACID THERAPEUTICS (2012)
Degradation of mRNAs that lack a stop codon: a decade of nonstop progress
A. Alejandra Klauer et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)
Control of human β-globin mRNA stability and its impact on beta-thalassemia phenotype
Isabel Peixeiro et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)
mRNA as gene therapeutic: How to control protein expression
Geertrui Tavernier et al.
JOURNAL OF CONTROLLED RELEASE (2011)
Palmitic Acid-Conjugated 21-Nucleotide siRNA Enhances Gene-Silencing Activity
Takanori Kubo et al.
MOLECULAR PHARMACEUTICS (2011)
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
Michael S. D. Kormann et al.
NATURE BIOTECHNOLOGY (2011)
Nanopore sensors for nucleic acid analysis
Bala Murali Venkatesan et al.
NATURE NANOTECHNOLOGY (2011)
Measurable impact of RNA quality on gene expression results from quantitative PCR
Joelle Vermeulen et al.
NUCLEIC ACIDS RESEARCH (2011)
DNase 2 Is the Main DNA-Degrading Enzyme of the Stratum Corneum
Heinz Fischer et al.
PLOS ONE (2011)
Control of poly(A) tail length
Christian R. Eckmann et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2011)
Analysing the eosinophil cationic protein - a clue to the function of the eosinophil granulocyte
Jonas Bystrom et al.
RESPIRATORY RESEARCH (2011)
Molecular Beacons: Powerful Tools for Imaging RNA in Living Cells
Ricardo Monroy-Contreras et al.
JOURNAL OF NUCLEIC ACIDS (2011)
Incorporation of measurement of DNA integrity into qPCR assays
Michael J. Brisco et al.
BIOTECHNIQUES (2010)
Oligonucleotide N3 ' -> P5 ' Phosphoramidates and Thio-Phoshoramidates as Potential Therapeutic Agents
Sergei M. Gryaznov
CHEMISTRY & BIODIVERSITY (2010)
The eight human canonical ribonucleases: Molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
Salvatore Sorrentino
FEBS LETTERS (2010)
Efficient delivery of intact phosphodiester oligonucleotides by poly-β-amino esters
K. Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Monitoring intracellular degradation of exogenous DNA using diffusion properties
Akira Sasaki et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Analysis of biological samples by capillary electrophoresis with laser induced fluorescence detection
Eva Szoko et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2010)
Recent Progress in Chemically Modified siRNAs
M. Gaglione et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2010)
Utilization of unlocked nucleic acid (UNA) to enhance siRNA performance in vitro and in vivo
Maria B. Laursen et al.
MOLECULAR BIOSYSTEMS (2010)
Genome editing with engineered zinc finger nucleases
Fyodor D. Urnov et al.
NATURE REVIEWS GENETICS (2010)
Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications
Malwina Strenkowska et al.
NEW JOURNAL OF CHEMISTRY (2010)
T2 Family ribonucleases: ancient enzymes with diverse roles
Natalie Luhtala et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Comparison and evaluation of RNA quantification methods using viral, prokaryotic, and eukaryotic RNA over a 104 concentration range
Roman Aranda et al.
ANALYTICAL BIOCHEMISTRY (2009)
Molecular Engineering of DNA: Molecular Beacons
Kemin Wang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)
Fluorescent Probes for Live-Cell RNA Detection
Gang Bao et al.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING (2009)
Dual Fluorescent Labeling Method to Visualize Plasmid DNA Degradation
Charudharshini Srinivasan et al.
BIOCONJUGATE CHEMISTRY (2009)
Irreversible Thermoinactivation of Ribonuclease-A by Soft-Hydrothermal Processing
Toru Miyamoto et al.
BIOTECHNOLOGY PROGRESS (2009)
TREX1 acts in degrading damaged DNA from drug-treated tumor cells
Chuan-Jen Wang et al.
DNA REPAIR (2009)
Acetic acid denaturing for RNA capillary polymer electrophoresis
Keiko Sumitomo et al.
ELECTROPHORESIS (2009)
Ribonuclease H: the enzymes in eukaryotes
Susana M. Cerritelli et al.
FEBS JOURNAL (2009)
Gene Regulation with Polyvalent siRNA-Nanoparticle Conjugates
David A. Giljohann et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
The Effect of Chemical Modification and Nanoparticle Formulation on Stability and Biodistribution of siRNA in Mice
Shan Gao et al.
MOLECULAR THERAPY (2009)
Polyvalent DNA Nanoparticle Conjugates Stabilize Nucleic Acids
Dwight S. Seferos et al.
NANO LETTERS (2009)
RNA major groove modifications improve siRNA stability and biological activity
Montserrat Terrazas et al.
NUCLEIC ACIDS RESEARCH (2009)
Selective Protection of Nuclease-Sensitive Sites in siRNA Prolongs Silencing Effect
Anton A. Volkov et al.
OLIGONUCLEOTIDES (2009)
New roles for the major human 3′-5′ exonuclease TREX1 in human disease
David Kavanagh et al.
CELL CYCLE (2008)
Differential Inhibitory Activities and Stabilisation of DNA Aptamers against the SARS Coronavirus Helicase
Ka To Shum et al.
CHEMBIOCHEM (2008)
Fluorescence correlation spectroscopy to study the degradation of oligonucleotides, both naked and complexed, to cationic carriers
K. Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2008)
Comparing in vitro and in vivo activity of 2′-O-[2-(methylamino)-2-oxoethyl]- and 2′-O-methoxyethyl-modified antisense oligonucleotides
Thazha P. Prakash et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Analyzing real-time PCR data by the comparative C-T method
Thomas D. Schmittgen et al.
NATURE PROTOCOLS (2008)
Biophysical modeling of fragment length distributions of DNA plasmids after X and heavy-ion irradiation analyzed by atomic force microscopy
Thilo Elsaesser et al.
RADIATION RESEARCH (2008)
ZAP-mediated mRNA degradation
Yiping Zhu et al.
RNA BIOLOGY (2008)
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
Joanna Kowalska et al.
RNA (2008)
Nucleic acid delivery: Where material sciences and bio-sciences meet
Katrien Remaut et al.
MATERIALS SCIENCE & ENGINEERING R-REPORTS (2007)
Study of modification pattern-RNAi activity relationships by using siRNAs modified with 4'-thioribonucleosides
Shuichi Hoshika et al.
CHEMBIOCHEM (2007)
Fluorescence correlation spectroscopy in living cells
Sally A. Kim et al.
NATURE METHODS (2007)
Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes
David B. Rozema et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Degradation of nuclear DNA by DNase II-like acid DNase in cortical fiber cells of mouse eye lens
Masaki Nakahara et al.
FEBS JOURNAL (2007)
Effective delivery with enhanced translational activity synergistically accelerates mRNA-based transfection
F. T. Zohra et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
DNase X is a glycosylphosphatidylinositol-anchored membrane enzyme that provides a barrier to endocytosis-mediated transfer of a foreign gene
Daisuke Shiokawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Small-molecule activators of RNase L with broad-spectrum antiviral activity
Chandar S. Thakur et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
ACTIBIND, a T2 RNase, competes with angiogenin and inhibits human melanoma growth, angiogenesis, and metastasis
Betty Schwartz et al.
CANCER RESEARCH (2007)
Eosinophil cationic protein (ECP) polymorphisms and association with asthma, s-ECP levels and related phenotypes
M. C. Munthe-Kaas et al.
ALLERGY (2007)
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine
K. Remaut et al.
BIOMACROMOLECULES (2007)
A plus U-rich instability elements differentially activate 5′-3′ and 3′-5′ mRNA decay
Elizabeth L. Murray et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Biochemical and cellular characteristics of the 3′→5′ exonuclease TREX2
Ming-Jiu Chen et al.
NUCLEIC ACIDS RESEARCH (2007)
The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis
Daria Maria Monti et al.
FEBS LETTERS (2007)
Pegylation of liposomes favours the endosornal degradation of the delivered phosphodiester oligonucleotides
K. Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2007)
Human lysosomal DNase II alpha contains two requisite PLD-signature (HxK) motifs: Evidence for a pseudodimeric structure of the active enzyme species
Patrick Schaefer et al.
PROTEIN SCIENCE (2007)
Acid DNases and their interest among apoptotic endonucleases
Marie-France Counis et al.
BIOCHIMIE (2006)
The RNase a superfamily: Generation of diversity and innate host defense
Kimberly D. Dyer et al.
MOLECULAR DIVERSITY (2006)
Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes
Katrien Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2006)
In situ analysis of single-stranded and duplex siRNA integrity in living cells
Koen Raemdonck et al.
BIOCHEMISTRY (2006)
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death
Dipanjan Chowdhury et al.
MOLECULAR CELL (2006)
Plasmid DNA and siRNA transfection of intestinal epithelial monolayers by electroporation
Esi B. Ghartey-Tagoe et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2006)
Control of mammalian translation by mRNA structure near caps
JR Babendure et al.
RNA (2006)
Chemical modification of siRNAs to improve serum stability without loss of efficacy
S Choung et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Quantification of mRNA in whole blood by assessing recovery of RNA and efficiency of cDNA synthesis
M Mitsuhashi et al.
CLINICAL CHEMISTRY (2006)
Genospheres: self-assembling nucleic acid-lipid nanoparticles suitable for targeted gene delivery
ME Hayes et al.
GENE THERAPY (2006)
Advances in fluorescent tracking of nucleic acids in living cells
RW Dirks et al.
BIOTECHNIQUES (2006)
Improving RNA interference in mammalian cells by 4′-thio-modified small interfering RNA (siRNA):: Effect on siRNA activity and nuclease stability when used in combination with 2′-O-alkyl modifications
P Dande et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
mRNA transfection of dendritic cells:: Synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level
M Mockey et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Delivery of phosphodiester oligonucleotides: Can DOTAP/DOPE liposomes do the trick?
K Remaut et al.
BIOCHEMISTRY (2006)
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
EWM Ng et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Differential inhibition of mRNA degradation pathways by novel cap analogs
E Grudzien et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Quantification of mRNA using real-time RT-PCR
Tania Nolan et al.
NATURE PROTOCOLS (2006)
Clinical analysis by microchip capillary electrophoresis
SFY Li et al.
CLINICAL CHEMISTRY (2006)
High potency silencing by single-stranded boranophosphate siRNA
Allison H. S. Hall et al.
NUCLEIC ACIDS RESEARCH (2006)
Improvements in siRNA properties mediated by 2 '-deoxy-2 '-fluoro-beta-D-arabinonucleic acid (FANA)
T Dowler et al.
NUCLEIC ACIDS RESEARCH (2006)
RNase L: Its biological roles and regulation
Shu-Ling Liang et al.
IUBMB LIFE (2006)
Dicing and slicing - The core machinery of the RNA interference pathway
SM Hammond
FEBS LETTERS (2005)
Crystal structures of RNase H bound to an RNA/DNA hybrid: Substrate specificity and metal-dependent catalysis
M Nowotny et al.
CELL (2005)
RNA degradation by the exosome is promoted by a nuclear polyade nylation complex
J LaCava et al.
CELL (2005)
Intracellular routing of plasmid DNA during non-viral gene transfer
D Lechardeur et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
Use of the nuclease inhibitor aurintricarboxylic acid (ATA) for improved non-viral intratumoral in vivo gene transfer by jet-injection
W Walther et al.
JOURNAL OF GENE MEDICINE (2005)
FRET-FCS as a tool to evaluate the stability of oligonucleotide drugs after intracellular delivery
K Remaut et al.
JOURNAL OF CONTROLLED RELEASE (2005)
Fully 2′-modified oligonucleotide duplexes with improved in vitro potency and stability compared to unmodified small interfering RNA
CR Allerson et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Studying biophysical barriers to DNA delivery by advanced light microscopy
SC De Smedt et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
DNA-based therapeutics and DNA delivery systems: A comprehensive review
SD Patil et al.
AAPS JOURNAL (2005)
Antisense oligonucleotides: The state of the art
T Aboul-Fadl
CURRENT MEDICINAL CHEMISTRY (2005)
Trashing the genome: The role of nucleases during apoptosis
K Samejima et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality
J Elmen et al.
NUCLEIC ACIDS RESEARCH (2005)
AU-rich elements and associated factors: are there unifying principles?
C Barreau et al.
NUCLEIC ACIDS RESEARCH (2005)
In vivo activity of nuclease-resistant siRNAs
JM Layzer et al.
RNA (2004)
DNA measurements by using fluorescence correlation spectroscopy and two-color fluorescence cross correlation spectroscopy
T Takagi et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2004)
2′-O-methyl-modified phosphorothioate antisense oligonucleotides have reduced non-specific effects in vitro
BH Yoo et al.
NUCLEIC ACIDS RESEARCH (2004)
Rapid quantification of DNase I activity in one-microliter serum samples
H Takeshita et al.
CLINICAL CHEMISTRY (2004)
Characterization of the human DNAS1L2 gene and the molecular mechanism for its transcriptional activation induced by inflammatory cytokines
D Shiokawa et al.
GENOMICS (2004)
Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2′-O-modified nucleic acid analogues
R Pattanayek et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Expression pattern of the deoxyribonuclease 1 gene:: lessons from the Dnase1 knockout mouse
M Napirei et al.
BIOCHEMICAL JOURNAL (2004)
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
KS Schmidt et al.
NUCLEIC ACIDS RESEARCH (2004)
RNA interference using boranophosphate siRNAs: structure-activity relationships
AHS Hall et al.
NUCLEIC ACIDS RESEARCH (2004)
Deoxyribonuclease II is a lysosomal barrier to transfection
DPG Howell et al.
MOLECULAR THERAPY (2003)
Pathophysiology and management of pulmonary infections in cystic fibrosis
RL Gibson et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
Degradation of double-stranded RNA by human pancreatic ribonuclease: Crucial role of noncatalytic basic amino acid residues
S Sorrentino et al.
BIOCHEMISTRY (2003)
L-DNase II activation by the 24 kDa apoptotic protease (AP24) in TNFα-induced apoptosis
V Altairac et al.
CELL DEATH AND DIFFERENTIATION (2003)
siRNA function in RNAi: A chemical modification analysis
YL Chiu et al.
RNA (2003)
Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens
S Nishimoto et al.
NATURE (2003)
2′-modified-2-thiothymidine oligonucleotides
KG Rajeev et al.
ORGANIC LETTERS (2003)
Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase I
HG Abdelhady et al.
NUCLEIC ACIDS RESEARCH (2003)
Bioconjugated nanoparticles for DNA protection from cleavage
XX He et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
F Czauderna et al.
NUCLEIC ACIDS RESEARCH (2003)
Structural requirements of human DNase IIα for formation of the active enzyme:: the role of the signal peptide, N-glycosylation, and disulphide bridging
KS MacLea et al.
BIOCHEMICAL JOURNAL (2003)
Regulation of α-globin mRNA stability
SA Waggoner et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2003)
Vitreous is a barrier in nonviral gene transfer by cationic lipids and polymers
L Pitkänen et al.
PHARMACEUTICAL RESEARCH (2003)
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin
J Harder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ribonuclease activity and RNA binding of recombinant human Dicer
P Provost et al.
EMBO JOURNAL (2002)
Deoxyribonuclease IIα is required during the phagocytic phase of apoptosis and its loss causes perinatal lethality
RJ Krieser et al.
CELL DEATH AND DIFFERENTIATION (2002)
Deoxyribonuclease I-like III is an inducible macrophage barrier to liposomal transfection
A Wilber et al.
MOLECULAR THERAPY (2002)
DNA transfection of macaque and murine respiratory tissue is greatly enhanced by use of a nuclease inhibitor
J Glasspool-Malone et al.
JOURNAL OF GENE MEDICINE (2002)
Revised structure of the active form of human deoxyribonuclease IIα
KS MacLea et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Human endothelial cells selectively express large amounts of pancreatic-type ribonuclease (RNase 1)
JBP Landre et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta
JZ Zhang et al.
NUCLEIC ACIDS RESEARCH (2002)
Fomivirsen - Clinical pharmacology and potential drug interactions
RS Geary et al.
CLINICAL PHARMACOKINETICS (2002)
Ca2+-sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids
H Pollard et al.
JOURNAL OF GENE MEDICINE (2001)
RNA analysis by ion-pair reversed-phase high performance liquid chromatography
Arezou Azarani et al.
NUCLEIC ACIDS RESEARCH (2001)
Characterization of human DNase I family endonucleases and activation of DNase γ during apoptosis
D Shiokawa et al.
BIOCHEMISTRY (2001)
Methods for visualizing RNA processing and transport pathways in living cells
RW Dirks et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2001)
Human RNase III is a 160-kDa protein involved in preribosomal RNA processing
HJ Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Analysis and purification of nucleic acids by ion-pair reversed-phase high-performance liquid chromatography
KH Hecker et al.
JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS (2000)
Efficient nonviral cutaneous transfection
J Glasspool-Malone et al.
MOLECULAR THERAPY (2000)
Functional characterization of DNase X, a novel endonuclease expressed in muscle cells
M Los et al.
BIOCHEMISTRY (2000)
Quantitation of supercoiled circular content in plasmid DNA solutions using a fluorescence-based method
M. S. Levy et al.
NUCLEIC ACIDS RESEARCH (2000)
Size-dependent DNA mobility in cytoplasm and nucleus
GL Lukacs et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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