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Material and Design Toolkit for Drug Delivery: State of the Art, Trends, and Challenges

期刊

ACS APPLIED MATERIALS & INTERFACES
卷 15, 期 48, 页码 55201-55231

出版社

AMER CHEMICAL SOC
DOI: 10.1021/acsami.3c10065

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drug delivery systems; nanoparticles; releasemechanisms; targeted delivery; surface modification

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The nanomaterial and toolkit have potential applications in improving human health and well-being, particularly in drug delivery systems. Current research focuses on using nanoscale materials as carriers to deliver therapeutic agents, addressing issues with conventional drug delivery systems. Although this technology shows promise, there are challenges to overcome in terms of safety, toxicity, efficacy, and delivery capacity.
The nanomaterial and related toolkit have promising applications for improving human health and well-being. Nanobased drug delivery systems use nanoscale materials as carriers to deliver therapeutic agents in a targeted and controlled manner, and they have shown potential to address issues associated with conventional drug delivery systems. They offer benefits for treating various illnesses by encapsulating or conjugating biological agents, chemotherapeutic drugs, and immunotherapeutic agents. The potential applications of this technology are vast; however, significant challenges exist to overcome such as safety issues, toxicity, efficacy, and insufficient capacity. This article discusses the latest developments in drug delivery systems, including drug release mechanisms, material toolkits, related design molecules, and parameters. The concluding section examines the limitations and provides insights into future possibilities.

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