4.7 Article

Site-selective synthesis and pharmacological elucidation of novel semi-synthetic analogues of koenimbine as a potential anti-inflammatory agent

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Summary: Neurodegenerative diseases mainly affect neurons, causing a loss of normal motor and cognitive functions. Plant extracts have gained interest as potential alternative medicines due to their various active components that can exert multiple pharmacological effects. Murraya koenigii leaves contain bioactive components with diverse pharmacological activities, including antioxidant, anti-inflammatory, anticancer, hepatoprotective, immunomodulatory, and neuroprotective effects.

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