☆ 4.7 Article

Moringa oleifera Leaves Protein Enhances Intestinal Permeability by Activating TLR4 Upstream Signaling and Disrupting Tight Junctions

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Nutrition & Dietetics

Moringa oleifera leaf polysaccharide alleviates experimental colitis by inhibiting inflammation and maintaining intestinal barrier

Hosameldeen Mohamed Husien et al.

Summary: The study demonstrated that MOLP has a protective effect against UC, as it can alleviate colonic pathological alterations and reduce inflammatory cell infiltration. It also showed that MOLP suppressed the loss of certain proteins in the mucosal layer while regulating specific mRNA expressions and signaling pathways related to inflammation.

FRONTIERS IN NUTRITION (2022)

添加到收藏夹

Review Immunology

The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target

Jia An et al.

Summary: Autoimmune diseases involve multiple tissues and organs, and the specific pathogenesis is not fully understood. The impaired intestinal mucosal barrier can disrupt immune homeostasis and trigger inflammation. However, the mechanisms by which the intestinal mucosal barrier regulates immune homeostasis and inflammation are not clear.

FRONTIERS IN IMMUNOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

Chemical Characterization and Nutritional Markers of South African Moringa oleifera Seed Oils

Kokoette Bassey et al.

Summary: South African Moringa oleifera seed oil is used as a nutritional supplement and water purifier, containing rich C-18 monounsaturated fatty acids.

MOLECULES (2022)

添加到收藏夹

Article Gastroenterology & Hepatology

Targeting the gut-liver-immune axis to treat cirrhosis

Thomas Henry Tranah et al.

Summary: Cirrhotic portal hypertension is characterized by the development of serious complications such as ascites, encephalopathy, bleeding, and hepatorenal syndrome, which are often caused by cirrhosis-associated immune dysfunction. Bacterial infections are common complications of chronic liver disease and are closely linked to dysbiosis of the intestinal microbiota.

GUT (2021)

添加到收藏夹

Review Obstetrics & Gynecology

Immunologic components in human milk and allergic diseases with focus on food allergy

Amy D. Burris et al.

Summary: Maternal diet influences the composition of human milk, which contains various immunomodulatory factors, microbiome, and food antigens; these factors play a crucial role in the development of allergic diseases, especially food allergies.

SEMINARS IN PERINATOLOGY (2021)

添加到收藏夹

Review Nutrition & Dietetics

The Functional Role of Lactoferrin in Intestine Mucosal Immune System and Inflammatory Bowel Disease

Ning Liu et al.

Summary: Inflammatory bowel disease (IBD) including UC and CD, is associated with intestinal mucosal immune disorder. Nutrients play a key role in inflammation, gut barrier integrity, and immune cell modulation in IBD. Lactoferrin (LF), a dietary bioactive component, has diverse biological functions and can help maintain intestine mucosal immune homeostasis.

FRONTIERS IN NUTRITION (2021)

添加到收藏夹

Article Dentistry, Oral Surgery & Medicine

E-cig might cause cell damage of oral mucosa

Ligia Angelo Tavares Schwarzmeier et al.

Summary: Significant differences were observed in micronuclei frequency between smokers and controls, while metanuclear anomalies such as karyolysis and karyorrhexis showed significant differences between various groups. E-cig and alcohol users, particularly former smokers, showed genotoxicity and cytotoxicity in oral mucosa cells, indicating potential for greater damage compared to non-users.

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY (2021)

添加到收藏夹

Article Immunology

Restraint Stress in Hypertensive Rats Activates the Intestinal Macrophages and Reduces Intestinal Barrier Accompanied by Intestinal Flora Dysbiosis

Tiantian Wang et al.

Summary: The results revealed that acute stress rapidly increased mean arterial pressure, especially in the SHR-stress group. Additionally, stress promoted an increase in epithelial permeability, reduction in tight junction-related protein expression, and aggregation of macrophages. Furthermore, stress led to significant increases in stress-related hormones and pro-inflammatory factor interleukin-6, along with a decrease in intestinal flora diversity and an imbalance in the F/B ratio.

JOURNAL OF INFLAMMATION RESEARCH (2021)

添加到收藏夹

Review Chemistry, Applied

Polysaccharides in natural products that repair the damage to intestinal mucosa caused by cyclophosphamide and their mechanisms: A review

Cuiping Li et al.

Summary: Studies have shown that polysaccharides can effectively prevent and improve CTX-induced intestinal mucosal injury and immune system disorders, which in turn enhances patients' treatment tolerance. Research in this area has made significant progress, providing a reference for further studies on the prevention of intestinal mucosal injury and nutritional intervention mechanisms.

CARBOHYDRATE POLYMERS (2021)

添加到收藏夹

Review Pharmacology & Pharmacy

Intestinal Mucosal Barrier Is Regulated by Intestinal Tract Neuro-Immune Interplay

Xin-yu You et al.

Summary: Interactions between nerves, immune cells, gut microbes, and various receptors play crucial roles in regulating intestinal inflammation and improving mucosal barrier function, which are important therapeutic targets for many diseases.

FRONTIERS IN PHARMACOLOGY (2021)

添加到收藏夹

Article Medicine, Research & Experimental

T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling

Ronald R. Marchelletta et al.

Summary: Genome-wide association studies have shown that loss-of-function mutations in PTPN2 increase the risk of chronic immune diseases like IBD and celiac disease. TCPTP, the gene product of PTPN2, plays a crucial role in maintaining intestinal barrier function by regulating tight junction protein localization and expression. The findings suggest a mechanism by which PTPN2 mutations contribute to IBD pathogenesis.

JOURNAL OF CLINICAL INVESTIGATION (2021)

添加到收藏夹

Article Plant Sciences

The miracle mix of Moringa: Status of Moringa research and development in Malawi

W. C. J. Sagona et al.

SOUTH AFRICAN JOURNAL OF BOTANY (2020)

添加到收藏夹

Review Neurosciences

Bidirectional Brain-gut-microbiota Axis in increased intestinal permeability induced by central nervous system injury

Xiao-jin Li et al.

CNS NEUROSCIENCE & THERAPEUTICS (2020)

添加到收藏夹

Review Immunology

Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract

Bolun Zhou et al.

FRONTIERS IN IMMUNOLOGY (2020)

添加到收藏夹

Letter Allergy

Rates of anaphylaxis for the most common food allergies

Bruce T. Miles et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2020)

添加到收藏夹

Article Gastroenterology & Hepatology

PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function

Marianne R. Spalinger et al.

GASTROENTEROLOGY (2020)

添加到收藏夹

Review Obstetrics & Gynecology

Neonatal intestinal dysbiosis

Mark A. Underwood et al.

JOURNAL OF PERINATOLOGY (2020)

添加到收藏夹

Review Pediatrics

Food Allergy: A Review

Divya Seth et al.

PEDIATRIC ANNALS (2020)

添加到收藏夹

Article Veterinary Sciences

Akkermansia muciniphila protects intestinal mucosa from damage caused by S. pullorum by initiating proliferation of intestinal epithelium

Linda Zhu et al.

VETERINARY RESEARCH (2020)

添加到收藏夹

Review Cell Biology

The protective roles of NLRP6 in intestinal epithelial cells

Jiuheng Yin et al.

CELL PROLIFERATION (2019)

添加到收藏夹

Review Cell Biology

Autophagy: roles in intestinal mucosal homeostasis and inflammation

Sabah Haq et al.

JOURNAL OF BIOMEDICAL SCIENCE (2019)

添加到收藏夹

Article Immunology

Intestinal damage precedes mucosal immune dysfunction in SIV infection

Tiffany Hensley-McBain et al.

MUCOSAL IMMUNOLOGY (2018)

添加到收藏夹

Article Physiology

Claudin-2-mediated cation and water transport share a common pore

R. Rosenthal et al.

ACTA PHYSIOLOGICA (2017)

添加到收藏夹

Review Physiology

Tight junctions of the proximal tubule and their channel proteins

Michael Fromm et al.

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2017)

添加到收藏夹

Review Allergy

Making the Most of In Vitro Tests to Diagnose Food Allergy

Alexandra F. Santos et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability

Karen L. Edelblum et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Mechanisms and consequences of intestinal dysbiosis

G. Adrienne Weiss et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Roles of intestinal epithelial cells in the maintenance of gut homeostasis

Ryu Okumura et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2017)

添加到收藏夹

Article Gastroenterology & Hepatology

The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction

Natalie J. Ronaghan et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2016)

添加到收藏夹

Review Rheumatology

Intestinal dysbiosis and innate immune responses in axial spondyloarthritis

Francesco Ciccia et al.

CURRENT OPINION IN RHEUMATOLOGY (2016)

添加到收藏夹

Article Genetics & Heredity

Molecular characterization and comparative expression analysis of two teleostean pro-inflammatory cytokines, IL-1β and IL-8, from Sebastes schlegeli

H. M. L. P. B. Herath et al.

GENE (2016)

添加到收藏夹

Article Allergy

Molecular and cellular mechanisms of food allergy and food tolerance

R. Sharon Chinthrajah et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Claudin-21 Has a Paracellular Channel Role at Tight Junctions

Hiroo Tanaka et al.

MOLECULAR AND CELLULAR BIOLOGY (2016)

添加到收藏夹

Review Immunology

Balancing Tolerance or Allergy to Food Proteins

Paul J. Bryce

TRENDS IN IMMUNOLOGY (2016)

添加到收藏夹

Article Biochemistry & Molecular Biology

Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Prashant K. Nighot et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

添加到收藏夹

Article Biochemistry & Molecular Biology

Model for the Architecture of Claudin-Based Paracellular Ion Channels through Tight Junctions

Hiroshi Suzuki et al.

JOURNAL OF MOLECULAR BIOLOGY (2015)

添加到收藏夹

Article Oncology

Numb modulates the paracellular permeability of intestinal epithelial cells through regulating apical junctional complex assembly and myosin light chain phosphorylation

Yongtao Yang et al.

EXPERIMENTAL CELL RESEARCH (2013)

添加到收藏夹

Article Biochemistry & Molecular Biology

Effects of Soybean Agglutinin on Mechanical Barrier Function and Tight Junction Protein Expression in Intestinal Epithelial Cells from Piglets

Li Pan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

添加到收藏夹

Article Multidisciplinary Sciences

Mannose-Binding Lectin Inhibits Monocyte Proliferation through Transforming Growth Factor-β1 and p38 Signaling Pathways

Yan Wang et al.

PLOS ONE (2013)

添加到收藏夹

Article Physiology

Meprin A impairs epithelial barrier function, enhances monocyte migration, and cleaves the tight junction protein occludin

Jialing Bao et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2013)

添加到收藏夹

Review Immunology

How Bacteria-Induced Apoptosis of Intestinal Epithelial Cells Contributes to Mucosal Inflammation

Martin Hausmann

INTERNATIONAL JOURNAL OF INFLAMMATION (2010)

添加到收藏夹

Article Biochemistry & Molecular Biology

Subcellular localization and physiological significance of intracellular mannan-binding protein

Motohiro Nonaka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

添加到收藏夹

Article Pathology

Molecular basis of epithelial barrier regulation - From basic mechanisms to clinical application

Jerrold R. Turner

AMERICAN JOURNAL OF PATHOLOGY (2006)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.