期刊
BRAIN SCIENCES
卷 13, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/brainsci13111580
关键词
aneurysmal subarachnoid hemorrhage; vascular neurosurgery; ruptured aneurysm; cisternostomy; cisternal drain; delayed cerebral ischemia; cerebral vasospasm; hydrocephalus
Cisternostomy and continuous postoperative cerebrospinal fluid drainage through a cisternal drain are important methods for treating aneurysmal subarachnoid hemorrhage (aSAH) and have potential benefits in reducing complications.
Aneurysmal subarachnoid hemorrhage (aSAH) provokes a cascade reaction that is responsible for early and delayed brain injuries mediated by intracranial hypertension, hydrocephalus, cerebral vasospasm (CV), and delayed cerebral ischemia (DCI), which result in increased morbidity and mortality. During open microsurgical repair, cisternal access is achieved essentially to gain proximal vascular control and aneurysm exposition. Cisternostomy also allows brain relaxation, removal of cisternal clots, and restoration of the CSF dynamics through the communication between the anterior and posterior circulation cisterns and the ventricular system, with the opening of the Membrane of Liliequist and lamina terminalis, respectively. Continuous postoperative CSF drainage through a cisternal drain (CD) is a valuable option for treating acute hydrocephalus and intracranial hypertension. Moreover, it efficiently removes the blood and toxic degradation products, with a potential benefit on CV, DCI, and shunt-dependent hydrocephalus. Finally, the CD is an effective pathway to administer vasoactive, fibrinolytic, and anti-oxidant agents and shows promising results in decreasing CV and DCI rates while minimizing systemic effects. We performed a comprehensive review to establish the adjuvant role of cisternostomy and CD performed in cases of direct surgical repair for ruptured intracranial aneurysms and their role in the prevention and treatment of aSAH complications.
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