A case of probable COVID-19 and mononucleosis reactivation complicating the presentation of travel-acquired measles

Summary: This study conducted a systematic review and meta-analysis of 36 publications, finding that the prevalence of active EBV, HHV6, HSV, CMV, HSV1, and VZV infection in COVID-19 patients was 41%, 3%, 28%, 25%, 22%, and 18%, respectively. The risk of active EBV infection in severe COVID-19 patients was 6 times higher than in non-COVID-19 controls. Prioritized research on co-infections of herpesviruses and SARS-CoV-2 is needed to determine who, when, and how to be tested, as well as how to effectively treat HHVs reactivations in acute and long COVID-19 patients.