相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The role of hepatokines in NAFLD
Norbert Stefan et al.
CELL METABOLISM (2023)
Looking ahead to potential incretin combination therapies for nonalcoholic steatohepatitis in patients with diabetes
Lucia Brodosi et al.
EXPERT OPINION ON PHARMACOTHERAPY (2023)
The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality
Tom H. Karlsen et al.
LANCET (2022)
A global view of the interplay between non-alcoholic fatty liver disease and diabetes
Norbert Stefan et al.
LANCET DIABETES & ENDOCRINOLOGY (2022)
Mitochondrial respiration is decreased in visceral but not subcutaneous adipose tissue in obese individuals with fatty liver disease
Kalliopi Pafili et al.
JOURNAL OF HEPATOLOGY (2022)
Subcutaneous Adipose Tissue Metabolic Function and Insulin Sensitivity in People With Obesity
Han-Chow E. Koh et al.
DIABETES (2021)
Nonalcoholic Fatty Liver Disease, Liver Fibrosis and Cardiovascular Disease in the Adult US Population
Stefano Ciardullo et al.
FRONTIERS IN ENDOCRINOLOGY (2021)
Understanding the mechanisms of reversal of type 2 diabetes
Roy Taylor et al.
LANCET DIABETES & ENDOCRINOLOGY (2019)
Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial
Michael E. J. Lean et al.
LANCET (2018)
Remission of Human Type 2 Diabetes Requires Decrease in Liver and Pancreas Fat Content but Is Dependent upon Capacity for β Cell Recovery
Roy Taylor et al.
CELL METABOLISM (2018)
Loss of Metabolic Flexibility in the Failing Heart
Qutuba G. Karwi et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2018)
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion
Sungguan Hong et al.
NATURE MEDICINE (2017)
NAFLD PNPLA3 and obesity: a synergistic relationship in NAFLD
Jake P. Mann et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Ketone Body Infusion With 3-Hydroxybutyrate Reduces Myocardial Glucose Uptake and Increases Blood Flow in Humans: A Positron Emission Tomography Study
Lars C. Gormsen et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2017)
Complex Energy Metabolic Changes in Heart Failure With Preserved Ejection Fraction and Heart Failure With Reduced Ejection Fraction
Kirstie A. De Jong et al.
CANADIAN JOURNAL OF CARDIOLOGY (2017)
Metabolic disturbances of non-alcoholic fatty liver resemble the alterations typical for type 2 diabetes
Bram Brouwers et al.
CLINICAL SCIENCE (2017)
Normalization of cardiac substrate utilization and left ventricular hypertrophy precede functional recovery in heart failure regression
Nikole J. Byrne et al.
CARDIOVASCULAR RESEARCH (2016)
Ketones Step to the Plate A Game Changer for Metabolic Remodeling in Heart Failure?
Stephen C. Kolwicz et al.
CIRCULATION (2016)
The Failing Heart Relies on Ketone Bodies as a Fuel
Gregory Aubert et al.
CIRCULATION (2016)
Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 study
Matthew James Armstrong et al.
LANCET (2016)
Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans
Artak Labadzhyan et al.
PLOS ONE (2016)
Myocardial Energy Substrate Metabolism in Heart Failure: From Pathways to Therapeutic Targets
Arata Fukushima et al.
CURRENT PHARMACEUTICAL DESIGN (2015)
Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes
Christopher J. Nolan et al.
DIABETES (2015)
Exercise and Weight Loss Improve Muscle Mitochondrial Respiration, Lipid Partitioning, and Insulin Sensitivity After Gastric Bypass Surgery
Paul M. Coen et al.
DIABETES (2015)
The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis
Chiara Saponaro et al.
NUTRIENTS (2015)
Clinical trial demonstrates exercise following bariatric surgery improves insulin sensitivity
Paul M. Coen et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Recent Advances in the Development of Acetyl-CoA Carboxylase (ACC) Inhibitors for the Treatment of Metabolic Disease
Matthew P. Bourbeau et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction
Beshay N. Zordoky et al.
PLOS ONE (2015)
AMP-Activated Protein Kinase: Maintaining Energy Homeostasis at the Cellular and Whole-Body Levels
D. Grahame Hardie
ANNUAL REVIEW OF NUTRITION, VOL 34 (2014)
Mechanical Unloading Promotes Myocardial Energy Recovery in Human Heart Failure
Anisha A. Gupte et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2014)
Abdominal subcutaneous adipose tissue insulin resistance and lipolysis in patients with non-alcoholic steatohepatitis
M. J. Armstrong et al.
DIABETES OBESITY & METABOLISM (2014)
New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease
Amirhossein Sahebkar et al.
EXPERT OPINION ON PHARMACOTHERAPY (2014)
ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4
Jun Mori et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Pressure-overload-induced heart failure induces a selective reduction in glucose oxidation at physiological afterload
Pavel Zhabyeyev et al.
CARDIOVASCULAR RESEARCH (2013)
Cardiac Insulin-Resistance and Decreased Mitochondrial Energy Production Precede the Development of Systolic Heart Failure After Pressure-Overload Hypertrophy
Liyan Zhang et al.
CIRCULATION-HEART FAILURE (2013)
AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer
D. Grahame Hardie
DIABETES (2013)
In Vivo Actions of Peroxisome Proliferator-Activated Receptors Glycemic control, insulin sensitivity, and insulin secretion
Roy Eldor et al.
DIABETES CARE (2013)
Mitochondrial dysfunction in non-alcoholic fatty liver disease and insulin resistance: Cause or consequence?
C. Garcia-Ruiz et al.
FREE RADICAL RESEARCH (2013)
The role of weight loss and exercise in correcting skeletal muscle mitochondrial abnormalities in obesity, diabetes and aging
Frederico G. S. Toledo et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2013)
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
Tadahiro Shimazu et al.
SCIENCE (2013)
Mechanisms for Insulin Resistance: Common Threads and Missing Links
Varman T. Samuel et al.
CELL (2012)
Short-Term Hyperinsulinemia and Hyperglycemia Increase Myocardial Lipid Content in Normal Subjects
Yvonne Winhofer et al.
DIABETES (2012)
Prevalence of Prediabetes and Diabetes and Metabolic Profile of Patients With Nonalcoholic Fatty Liver Disease (NAFLD)
Carolina Ortiz-Lopez et al.
DIABETES CARE (2012)
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Zheng Sun et al.
NATURE MEDICINE (2012)
Targeting fatty acid and carbohydrate oxidation - A novel therapeutic intervention in the ischemic and failing heart
Jagdip S. Jaswal et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy
Christian Riehle et al.
CIRCULATION RESEARCH (2011)
Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity A Driver for Ectopic Fat Deposition?
Siobhan E. McQuaid et al.
DIABETES (2011)
Fatty Acids, Obesity, and Insulin Resistance: Time for a Reevaluation
Fredrik Karpe et al.
DIABETES (2011)
Prevalence, Metabolic Features, and Prognosis of Metabolically Healthy Obese Italian Individuals The Cremona Study
Giliola Calori et al.
DIABETES CARE (2011)
SIRT3 Deficiency and Mitochondrial Protein Hyperacetylation Accelerate the Development of the Metabolic Syndrome
Matthew D. Hirschey et al.
MOLECULAR CELL (2011)
Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology
Erik Arner et al.
DIABETES (2010)
Insulin Regulates Adipocyte Lipolysis via an Akt-Independent Signaling Pathway
Sarah M. Choi et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Myocardial Fatty Acid Metabolism in Health and Disease
Gary D. Lopaschuk et al.
PHYSIOLOGICAL REVIEWS (2010)
Surrogate markers of insulin resistance: A review
Bhawna Singh et al.
WORLD JOURNAL OF DIABETES (2010)
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
Bei B. Zhang et al.
CELL METABOLISM (2009)
Overexpression of Carnitine Palmitoyltransferase-1 in Skeletal Muscle Is Sufficient to Enhance Fatty Acid Oxidation and Improve High-Fat Diet-Induced Insulin Resistance
Clinton R. Bruce et al.
DIABETES (2009)
Muscle-Derived Angiopoietin-Like Protein 4 Is Induced by Fatty Acids via Peroxisome Proliferator-Activated Receptor (PPAR)-δ and Is of Metabolic Relevance in Humans
Harald Staiger et al.
DIABETES (2009)
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
Carles Canto et al.
NATURE (2009)
Substrate Utilization by the Failing Human Heart by Direct Quantification Using Arterio-Venous Blood Sampling
Junichi Funada et al.
PLOS ONE (2009)
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
Elisa Fabbrini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Exercise-induced alterations in intramyocellular lipids and insulin resistance:: the athlete's paradox revisited
John J. Dube et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
Timothy R. Koves et al.
CELL METABOLISM (2008)
Pathogenesis of type 2 diabetes: tracing the reverse route from cure to cause
R. Taylor
DIABETOLOGIA (2008)
The PPAR trio: Regulators of myocardial energy metabolism in health and disease
Jose A. Madrazo et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
The absence of endogenous lipid oxidation in early stage heart failure exposes limits in lipid storage and turnover
J. Michael O'Donnell et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver
Gianluca Perseghin et al.
HEPATOLOGY (2008)
Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy
Danilo Neglia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
Amalia Gastaldelli et al.
GASTROENTEROLOGY (2007)
Mechanisms of disease - The failing heart - An engine out of fuel
Stefan Neubauer
NEW ENGLAND JOURNAL OF MEDICINE (2007)
Decreased myocardial free fatty acid uptake in patients with idiopathic dilated cardiomyopathy:: Evidence of relationship with insulin resistance and left ventricular dysfunction
Helena Tuunanen et al.
JOURNAL OF CARDIAC FAILURE (2006)
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α
Zoltan Arany et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms
E Bugianesi et al.
DIABETOLOGIA (2005)
Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts
PK Mazumder et al.
DIABETES (2004)
Utilization of triacylglycerol-rich lipoproteins by the working rat heart: routes of uptake and metabolic fates
YG Niu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease
S Klein et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women
LR Peterson et al.
CIRCULATION (2004)
Fatty acid mobilization from adipose tissue during exercise
JF Horowitz
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2003)
Impact of glucose intolerance and insulin resistance on cardiac structure and function - Sex-related differences in the Framingham Heart Study
MK Rutter et al.
CIRCULATION (2003)
Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways
L Hue et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Long- and medium-chain fatty acid oxidation is increased in exercise-trained human skeletal muscle
JK Kim et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2002)
The effects of increasing exercise intensity on muscle fuel utilisation in humans
LJC van Loon et al.
JOURNAL OF PHYSIOLOGY-LONDON (2001)
Whole body and abdominal lipolytic sensitivity to epinephrine is suppressed in upper body obese women
JF Horowitz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
Fuel selection in human skeletal muscle in insulin resistance - A reexamination
DE Kelley et al.
DIABETES (2000)
A nuclear complex containing PPAR alpha/RXR alpha is markedly downregulated in the hypertrophied rat left ventricular myocardium with normal systolic function
H Kanda et al.
HEART AND VESSELS (2000)