期刊
JOURNAL OF SAUDI CHEMICAL SOCIETY
卷 20, 期 1, 页码 101-106出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.jscs.2014.09.002
关键词
Nano TiO2; Oxindole; Isatin; Indole; Reusable catalyst
资金
- Research Council of Alzahra University
Nano TiO2 supported on SiO2 (Nano TiO2/SiO2) as a solid Lewis acid, was found to be an effective and reusable catalyst for the condensation reaction of indoles with isatins to afford the corresponding bis(indolyl)oxindoles at 50 degrees C under solvent-free conditions. The efficacy of the catalyst was also examined in the reaction of pyrrole and 3-methylindole with isatin. The catalyst has been recovered and its reusability confirmed in 5 runs. A plausible mechanism of condensation has also been suggested. (C) 2014 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.
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