4.5 Article

The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Endocrinology & Metabolism

Overview of the 2022 WHO Classification of Thyroid Neoplasms

Zubair W. Baloch et al.

Summary: This review summarizes the changes in the 5th edition of the WHO Classification of Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new classification provides a more detailed understanding of the different types of thyroid tumors based on their cell of origin, pathologic features, molecular profiles, and biological behavior. It also introduces new categories, such as thyroid follicular nodular disease, non-invasive follicular thyroid neoplasm with papillary-like nuclear features, and high-grade differentiated thyroid carcinomas. The classification emphasizes the importance of biomarkers in diagnosis and prognosis.

ENDOCRINE PATHOLOGY (2022)

Article Oncology

The BRAFV600E Mutation Is Not a Risk Factor for More Aggressive Tumor Behavior in Radiogenic and Sporadic Papillary Thyroid Carcinoma at a Young Age

Liudmyla Zurnadzhy et al.

Summary: The frequency of BRAF(V600E) in young Ukrainian patients with radiogenic and sporadic papillary thyroid carcinomas increases with age, but does not confer a more aggressive course regardless of tumor etiology. Major clinicopathological differences between radiogenic and sporadic PTCs are observed among the BRAF(V600E)-negative tumors.

CANCERS (2021)

Review Pharmacology & Pharmacy

The primary cilium: Its role as a tumor suppressor organelle

Estanislao Peixoto et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Review Medicine, Research & Experimental

Papillary Thyroid Cancer-Aggressive Variants and Impact on Management: A Narrative Review

Andres Coca-Pelaz et al.

ADVANCES IN THERAPY (2020)

Article Biochemistry & Molecular Biology

Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer

Junguee Lee et al.

ONCOGENE (2018)

Review Medicine, General & Internal

Thyroid cancer

Maria E. Cabanillas et al.

LANCET (2016)

Review Medicine, General & Internal

Biologic and Clinical Perspectives on Thyroid Cancer

James A. Fagin et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Anatomy & Morphology

Comparative study of the primary cilia in thyrocytes of adult mammals

J. C. Utrilla et al.

JOURNAL OF ANATOMY (2015)

Review Oncology

Time to re-consider the meaning of BRAF V600E mutation in papillary thyroid carcinoma

Greta Gandolfi et al.

INTERNATIONAL JOURNAL OF CANCER (2015)