MCM-41@CPTMS as an Efficient and High-Performance Catalyst for One-Pot Construction of Indeno[1,2-b]quinolin-8-one Derivatives

In this work, MCM-41@CPTMS nanoparticles were readily prepared and evaluated as acidic nanosilica spheres for the synthesis of indeno[1,2-b]quinolinone derivatives through one-pot three-component reaction of 1-naphthylamine, aromatic aldehydes and 1,3-indandione. A high surface area, a hexagonal array of uniform mesoporous, high thermal stability, recyclability, nontoxicity and the easy separation of the nanocatalyst, make this nanocatalyst very useful for the synthesis of organic compounds. Mesoporous silica nanoparticles (MSN) was prepared easily and affirmed to be effective and prepared the products with excellent yields under reflux conditions. The structure of obtained nanoparticles was characterized by FE-SEM, TEM, EDX, FT-IR, XRD, TGA and BET. This synthetic protocol provides several benefits such as excellent yields in short reaction times (83-97 %),saving costs, reusability of the catalyst (five runs), and low catalyst loading. A novel, easy, fast and efficient strategy for the synthesis of indeno[1,2-b]quinolinone derivatives by using MCM-41@CPTMS as catalyst is described. A high surface area, a hexagonal array of uniform mesoporous, high thermal stability, recyclability, nontoxicity and the easy separation of the nanocatalyst, make it very useful for the synthesis of the indeno[1,2-b]quinolinone.**image

Automated summary

In this study, acidic nanosilica spheres were prepared and used as a catalyst for the synthesis of indeno[1,2-b]quinolinone derivatives. The nanocatalyst exhibited high surface area, uniform mesoporous structure, high thermal stability, recyclability, nontoxicity, and easy separation. The synthesis reaction showed excellent yields with short reaction times, cost savings, and low catalyst loading.