相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Cell cycle involvement in cancer therapy; WEE1 kinase, a potential target as therapeutic strategy
Sajjad Vakili-Samiani et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2022)
Property-Unmatched Decoys in Docking Benchmarks
Reed M. Stein et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2021)
RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences
Stephen K. Burley et al.
NUCLEIC ACIDS RESEARCH (2021)
OPLS4: Improving Force Field Accuracy on Challenging Regimes of Chemical Space
Chao Lu et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2021)
Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer
Peter Q. Huang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Antitumor effect of a WEE1 inhibitor and potentiation of olaparib sensitivity by DNA damage response modulation in triple-negative breast cancer
Dong-Hyeon Ha et al.
SCIENTIFIC REPORTS (2020)
Development and Characterization of a Wee1 Kinase Degrader
Zhengnian Li et al.
CELL CHEMICAL BIOLOGY (2020)
Multiple Defects Sensitize p53-Deficient Head and Neck Cancer Cells to the WEE1 Kinase Inhibition
Ahmed Diab et al.
MOLECULAR CANCER RESEARCH (2019)
Enhancement of chemosensitivity by WEE1 inhibition in EGFR-TKIs resistant non-small cell lung cancer
Di Liu et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
ChEMBL: towards direct deposition of bioassay data
David Mendez et al.
NUCLEIC ACIDS RESEARCH (2019)
Strategic development of AZD1775, a Wee1 kinase inhibitor, for cancer therapy
Siqing Fu et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2018)
Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors
Jin-Yi Zhu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
WEE1 inhibition by MK1775 as a single-agent therapy inhibits ovarian cancer viability
Minghui Zhang et al.
ONCOLOGY LETTERS (2017)
Molecular Pathways: Targeting the Protein Kinase Wee1 in Cancer
Jill J. J. Geenen et al.
CLINICAL CANCER RESEARCH (2017)
Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors
Suzanne Leijen et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Targeting WEE1 Kinase in Cancer
Christopher J. Matheson et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2016)
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Samuel Genheden et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
Selective Targeting of the G2/M Cell Cycle Checkpoint to Improve the Therapeutic Index of Radiotherapy
M. T. Dillon et al.
CLINICAL ONCOLOGY (2014)
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
G. Madhavi Sastry et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2013)
Multiple ligand docking by Glide: implications for virtual second-site screening
Marton Vass et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2012)
Graphical analysis of pH-dependent properties of proteins predicted using PROPKA
Michal Rostkowski et al.
BMC STRUCTURAL BIOLOGY (2011)
Virtual Fragment Docking by Glide: a Validation Study on 190 Protein-Fragment Complexes
Mark Sandor et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Fast and Accurate Predictions of Binding Free Energies Using MM-PBSA and MM-GBSA
Giulio Rastelli et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
Towards the comprehensive, rapid, and accurate prediction of the favorable tautomeric states of drug-like molecules in aqueous solution
Jeremy R. Greenwood et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2010)
Epik:: a software program for pK a prediction and protonation state generation for drug-like molecules
John C. Shelley et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2007)
Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
Richard A. Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
A hierarchical approach to all-atom protein loop prediction
MP Jacobson et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Glide: A new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy
RA Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
TA Halgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)