4.6 Article

An artificial protein cage made from a 12-membered ring

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Near-Miss Symmetric Polyhedral Cages

Bernard M. A. G. Piette et al.

Summary: After discovering nearly symmetric protein cages through experiments, we introduce the concept of homogeneous symmetric congruent equivalent near-miss polyhedral cages made of P-gons. We utilize group theory to parameterize the feasible configurations and numerically minimize the irregularity of the P-gons to generate all such polyhedral cages for P=6 to P=20, with deformation up to 10%.

SYMMETRY-BASEL (2023)

Article Chemistry, Multidisciplinary

Artificial Protein Cage with Unusual Geometry and RegularlyEmbedded Gold Nanoparticles

Karolina Majsterkiewicz et al.

Summary: The structure of an artificial protein cage triggered by gold nanoparticles was successfully predicted, and it was discovered that each cage contains gold nanoparticles, which can be used to achieve regular arrangement of the nanoparticles.

NANO LETTERS (2022)

Review Multidisciplinary Sciences

The road to fully programmable protein catalysis

Sarah L. Lovelock et al.

Summary: Designing efficient enzymes has a profound impact on chemistry, biotechnology, and medicine. Recent advances in protein engineering and computational methods have made it possible to optimize protein structures and generate efficient enzymes through laboratory evolution. Emerging methods like deep learning hold promise for improving the accuracy of protein design models.

NATURE (2022)

Article Biochemistry & Molecular Biology

Search and sequence analysis tools services from EMBL-EBI in 2022

Fabio Madeira et al.

Summary: The EMBL-EBI search and sequence analysis tools frameworks allow integrated access to data resources and core bioinformatics analytical tools. These tools can be interacted with through user-friendly web applications and APIs. Recent improvements have been made to accommodate the increasing data requirements during the COVID-19 pandemic.

NUCLEIC ACIDS RESEARCH (2022)

Article Multidisciplinary Sciences

Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models

Alexander A. Cohen et al.

SCIENCE (2022)

Article Cell Biology

Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine

Prabhu S. Arunachalam et al.

Summary: This study demonstrates the durable protection provided by the AS03-adjuvanted RBD-I53-50 nanoparticle vaccine against the Omicron BA.1 variant, as well as high neutralizing antibody titers against both the Omicron and Beta variants. The vaccine also induces persistent neutralization against a panel of sarbecoviruses and elicits persistent memory T and B cell responses.

SCIENCE TRANSLATIONAL MEDICINE (2022)

Article Biochemistry & Molecular Biology

3D variability analysis: Resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM

Ali Punjani et al.

Summary: 3DVA is an algorithm that fits a linear subspace model of conformational change to high-resolution cryo-EM data, enabling the resolution and visualization of detailed molecular motions of proteins. It has been shown to successfully resolve multiple flexible motions in various protein complexes, providing new biological insights from single particle cryo-EM data.

JOURNAL OF STRUCTURAL BIOLOGY (2021)

Article Multidisciplinary Sciences

Topaz-Denoise: general deep denoising models for cryoEM and cryoET

Tristan Bepler et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

An ultra-stable gold-coordinated protein cage displaying reversible assembly

Ali D. Malay et al.

NATURE (2019)

Article Biochemical Research Methods

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Tristan Bepler et al.

NATURE METHODS (2019)

Article Multidisciplinary Sciences

Structural puzzles in virology solved with an overarching icosahedral design principle

Reidun Twarock et al.

NATURE COMMUNICATIONS (2019)

Letter Biochemical Research Methods

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

Shawn Q. Zheng et al.

NATURE METHODS (2017)

Article Biochemical Research Methods

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

Ali Punjani et al.

NATURE METHODS (2017)

Review Multidisciplinary Sciences

The coming of age of de novo protein design

Po-Ssu Huang et al.

NATURE (2016)

Article Chemistry, Multidisciplinary

Gold Nanoparticle-Induced Formation of Artificial Protein Capsids

Ali D. Malay et al.

NANO LETTERS (2012)