4.7 Article

Gas-phase odor mixture quantification based on relative comparison method using multiple olfactory receptors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

New insights on the adsorption of floral odorants on Apis cerana cerana olfactory receptor AcerOr1: Theoretical modeling and thermodynamic study

Ismahene Ben Khemis et al.

Summary: The Asian honeybee Apis cerana cerana's olfactory system plays a crucial role in its survival activities, and the olfactory receptors are essential for odorant detection, recognition, and coding. Studying the olfactory system of Asian honeybees can provide valuable insights into insect olfactory perception. The Apis cerana cerana olfactory receptor AcerOr1 showed high sensitivity and discrimination power for undecanoic acid, 1-octyl alcohol, and 1-nonanol at concentrations of 10-7 mol/L. The adsorption energy values ranged from 17.91 to 24.00 kJ/mol, indicating the exothermic and physisorption nature of the studied floral odorants on AcerOr1.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2023)

Article Biophysics

Extending lifetime of gas-phase odor biosensor using liquid thickness control and liquid exchange

Hongchao Deng et al.

Summary: In this study, a feedback control structure and liquid exchange technique were proposed to improve the lifetime of odor biosensors. By controlling the thickness of the liquid layer above the cells and performing liquid exchange, the lifetime of the biosensors was successfully extended and better sensor responses were achieved.

BIOSENSORS & BIOELECTRONICS (2022)

Article Biochemistry & Molecular Biology

Indirect characterizations of mOR-EG: Modeling analysis of five concentration-olfactory response curves via an advanced monolayer adsorption model

Ismahene Ben Khemis et al.

Summary: This study investigated the adsorption process and mechanism of apocynin, guaia-cylacetone, homovanillyl alcohol, 4-ethylguaiacol, and homoguaiacol molecules on the mouse eugenol olfactory receptor mOR-EG. The results showed that these odorants were adsorbed through a multi-molecular mechanism, forming weak bonds with the amino acid residues of mOR-EG binding pockets. The study also characterized mOR-EG through analyzing the size distributions of binding cavities and adsorption energy distributions.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Engineering, Electrical & Electronic

Study of Liquid Film Thickness for Gas Phase Odor Biosensor

Hongchao Deng et al.

Summary: This study developed a gas phase odor biosensor with variable liquid film thickness, where the change in liquid layer thickness was reflected in the impedance change between two electrodes. Thinner liquid film resulted in greater response and faster peak time. Withdrawing the buffer solution step by step was preferred for realizing a stable thin liquid film state. The thin liquid film significantly improved response but weakened stability.

IEEE SENSORS JOURNAL (2022)

Article Biochemistry & Molecular Biology

Theoretical study of the olfactory perception of floral odorant on OR10J5 and Olfr16 using the grand canonical ensemble in statistical physics approach

Ismahene Ben Khemis et al.

Summary: This study examines the evolution of physico-chemical parameters involved in the human and mouse smelling of a floral scent using experimental dose-response curves of lyral molecules on specific olfactory receptors. The results suggest a physisorption process with adsorption energies below 11 kJ/mol, and advanced modeling provides valuable information on the docking of lyral molecules on olfactory receptors.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Chemistry, Physical

Interpretation the olfactory perception of musk tibetene, muscone and dihydrocivetone on the human musk olfactory receptor OR5AN1 via an advanced statistical physics modeling

Ismahene Ben Khemis et al.

Summary: The adsorption mechanism of musk tibetene, muscone, and dihydrocivetone on the human musk olfactory receptor OR5AN1 has been investigated using statistical physics. Two advanced adsorption models derived from statistical physics approach were fitted to experimental data, showing a good correlation. The findings provide important insights into the adsorption process and contribute to a better understanding of olfaction.

JOURNAL OF MOLECULAR LIQUIDS (2022)

Article Biochemistry & Molecular Biology

Physico-chemical investigations of human olfactory receptors OR10G4 and OR2B11 activated by vanillin, ethyl vanillin, coumarin and quinoline molecules using statistical physics method

Ismahene Ben Khemis et al.

Summary: This research provides a detailed analysis of the adsorption mechanism and energy characteristics of vanillin, ethyl vanillin, coumarin, and quinoline molecules on olfactory receptors, using statistical physics modeling. The findings reveal the different orientations and energy values associated with the adsorption process, shedding light on the molecular-level understanding of olfaction mechanism.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Article Chemistry, Analytical

Interpretation of Quartz Crystal Microbalance Behavior with Viscous Film Using a Mason Equivalent Circuit

Sawit Na Songkhla et al.

Summary: In odor sensing using Quartz Crystal Microbalances (QCMs), the sensing film plays a vital role in sensor sensitivity and selectivity. The response of QCMs to sorption can be modeled using a Mason equivalent circuit, showing potential positive frequency shifts in certain cases. Experimental results demonstrate that the frequency change depends on the viscosity and thickness of the coating when exposed to water.

CHEMOSENSORS (2021)

Article Chemistry, Physical

Adsorption of 2-phenylethanethiol on two broadly tuned human olfactory receptors OR1A1 and OR2W1: Interpretation of the effect of copper ions via statistical physics monolayer adsorption model

Ismahene Ben Khemis et al.

Summary: The presence of copper ions was found to have a negative allosteric effect on the activation of OR1A1 by 2-phenylethanethiol, while it showed an orthosteric competitive effect on the activation of OR2W1. The study revealed that the adsorption process is based on physical adsorption, with varying adsorption energies in different systems. The experimental results provided insight into the distribution of olfactory receptor site sizes and adsorption energy.

JOURNAL OF MOLECULAR LIQUIDS (2021)

Article Chemistry, Analytical

A wireless-electrodeless quartz crystal microbalance method for non-enzymatic glucose monitoring

Daqi Chen et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Article Engineering, Electrical & Electronic

Odor Discrimination Using Cell-Based Odor Biosensor System With Fluorescent Image Processing

Yuji Sukekawa et al.

IEEE SENSORS JOURNAL (2019)

Article Engineering, Electrical & Electronic

Signal Processing of Vector Network Analyzer Measurement for Quartz Crystal Microbalance With Viscous Damping

Sawit Na Songkhla et al.

IEEE SENSORS JOURNAL (2019)

Article Nanoscience & Nanotechnology

Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors

Thanihaichelvan Murugathas et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Chemistry, Analytical

A wireless-electrodeless quartz crystal microbalance with dissipation DMMP sensor

Daqi Chen et al.

SENSORS AND ACTUATORS B-CHEMICAL (2018)

Article Multidisciplinary Sciences

Vapor detection and discrimination with a panel of odorant receptors

Hitoshi Kida et al.

NATURE COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Cell-Based Odorant Sensor Array for Odor Discrimination Based on Insect Odorant Receptors

Maneerat Termtanasombat et al.

JOURNAL OF CHEMICAL ECOLOGY (2016)

Article Chemistry, Multidisciplinary

An Organocobalt-Carbon Nanotube Chemiresistive Carbon Monoxide Detector

Sophie F. Liu et al.

ACS SENSORS (2016)

Article Multidisciplinary Sciences

DoOR 2.0-Comprehensive Mapping of Drosophila melanogaster Odorant Responses

Daniel Muench et al.

SCIENTIFIC REPORTS (2016)

Article Biophysics

Cell-based microfluidic platform for mimicking human olfactory system

Seung Hwan Lee et al.

BIOSENSORS & BIOELECTRONICS (2015)

Article Biophysics

Novel cell-based odorant sensor elements based on insect odorant receptors

Hidefumi Mitsuno et al.

BIOSENSORS & BIOELECTRONICS (2015)

Article Chemistry, Multidisciplinary

Chemical Vapor Detection Using a Reconstituted Insect Olfactory Receptor Complex

Koji Sato et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Multidisciplinary Sciences

Humans Can Discriminate More than 1 Trillion Olfactory Stimuli

C. Bushdid et al.

SCIENCE (2014)

Review Chemistry, Analytical

Ethylene detection methods in post-harvest technology: A review

F. Caprioli et al.

SENSORS AND ACTUATORS B-CHEMICAL (2014)

Review Entomology

Odorant Reception in Insects: Roles of Receptors, Binding Proteins, and Degrading Enzymes

Walter S. Leal

ANNUAL REVIEW OF ENTOMOLOGY, VOL 58 (2013)

Article Multidisciplinary Sciences

Ultrasensitive fluorescent proteins for imaging neuronal activity

Tsai-Wen Chen et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

A Conserved Dedicated Olfactory Circuit for Detecting Harmful Microbes in Drosophila

Marcus C. Stensmyr et al.

Article Engineering, Electrical & Electronic

Odor Approximation Using Mass Spectrometry

Takamichi Nakamoto et al.

IEEE SENSORS JOURNAL (2012)

Article Multidisciplinary Sciences

Highly sensitive and selective odorant sensor using living cells expressing insect olfactory receptors

Nobuo Misawa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Chemistry, Analytical

Real-time reference method in odor recorder under environmental change

T Yamanaka et al.

SENSORS AND ACTUATORS B-CHEMICAL (2003)