相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Parkinson's Disease Modification through Abl Kinase Inhibition: An Opportunity
Milton H. Werner et al.
MOVEMENT DISORDERS (2022)
Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect
Zichao Yang et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2022)
Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models
Jack Wuyang Jin et al.
COMMUNICATIONS BIOLOGY (2021)
Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology
David K. Simon et al.
CLINICS IN GERIATRIC MEDICINE (2020)
Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease A Phase 2 Randomized Clinical Trial
Fernando. L. Pagan et al.
JAMA NEUROLOGY (2020)
Clinical Features of Parkinson's Disease: The Evolution of Critical Symptoms
Csaba Varadi
BIOLOGY-BASEL (2020)
Parkinson's disease: etiopathogenesis and treatment
Joseph Jankovic et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)
Computational studies of potent covalent inhibitors on wild type or T790M/L858R mutant epidermal growth factor receptor
Zichao Yang et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Design, synthesis and evaluation of pentacycloundecane and hexacycloundecane propargylamine derivatives as multifunctional neuroprotective agents
Frank T. Zindo et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect
Lv Tang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Current Progress in CAR-T Cell Therapy for Solid Tumors
Shuo Ma et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
Synthesis of new heterocyclic compounds based on pyrazolopyridine scaffold and evaluation of their neuroprotective potential in MPP+-induced neurodegeneration
Jabrane Jouha et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
A natural product from Cannabis sativa subsp sativa inhibits homeodomain- interacting protein kinase 2 (HIPK2), attenuating MPP+-induced apoptosis in human neuroblastoma SH-SY5Y cells
Guan Wang et al.
BIOORGANIC CHEMISTRY (2017)
c-Abl-p38α signaling plays an important role in MPTP-induced neuronal death
R. Wu et al.
CELL DEATH AND DIFFERENTIATION (2016)
Off-Target Effects of BCR-ABL and JAK2 Inhibitors
Myke R. Green et al.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2016)
Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration
Saurav Brahmachari et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
The Capable ABL: What Is Its Biological Function?
Jean Y. J. Wang
MOLECULAR AND CELLULAR BIOLOGY (2014)
A novel tyrosine kinase inhibitor AMN107 (nilotinib) normalizes striatal motor behaviors in a mouse model of Parkinson's disease
Akie Tanabe et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease
Senthilkumar S. Karuppagounder et al.
SCIENTIFIC REPORTS (2014)
Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of -synuclein in Parkinsons disease models
Michaeline L. Hebron et al.
HUMAN MOLECULAR GENETICS (2013)
Novel Regulation of Parkin Function through c-Abl-Mediated Tyrosine Phosphorylation: Implications for Parkinson's Disease
Syed Z. Imam et al.
JOURNAL OF NEUROSCIENCE (2011)
Fast and Accurate Predictions of Binding Free Energies Using MM-PBSA and MM-GBSA
Giulio Rastelli et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
Han Seok Ko et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Improved side-chain torsion potentials for the Amber ff99SB protein force field
Kresten Lindorff-Larsen et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)
Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes
Richard A. Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL
E. Weisberg et al.
BRITISH JOURNAL OF CANCER (2006)
Novel procedure for modeling ligand/receptor induced fit effects
W Sherman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Integrated modeling program, applied chemical theory (IMPACT)
JL Banks et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
E Weisberg et al.
CANCER CELL (2005)
Development and testing of a general amber force field
JM Wang et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Distribution of STI-571 to the brain is limited by P-glycoprotein-mediated efflux
HQ Dai et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models
PA Kollman et al.
ACCOUNTS OF CHEMICAL RESEARCH (2000)
分享论文
