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Vaccine inequity: a threat to Africa's recovery from COVID-19

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Article Immunology

'Vaccinate my village' strategy in Malawi: an effort to boost COVID-19 vaccination

Ghanshyam Sethy et al.

Summary: To improve COVID-19 vaccine uptake, an innovative 'vaccinate my village' strategy using door-to-door vaccination by Health Surveillance Assistants (HSA) was implemented in Malawi. The study found that this strategy significantly increased the number of vaccine doses administered and the proportion of the population receiving at least one dose of the COVID-19 vaccine. District-wise coverage of the vaccine also improved after the implementation of this strategy.

EXPERT REVIEW OF VACCINES (2023)

Article Public, Environmental & Occupational Health

COVID-19 vaccine equity in Africa

Natasha Turyasingura et al.

Summary: The COVID-19 pandemic has been the main topic in global health discussions since early 2020. Vaccine development against SARS-CoV-2 has been successful, but the distribution has not been fair, especially in African countries. This article highlights the low vaccination rates in Africa and suggests Africa-based research and development as a sustainable solution for vaccine equity.

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE (2023)

Review Immunology

COVID-19 vaccines and a perspective on Africa

Alberto Mantovani et al.

Summary: This article reviews the modes of action of COVID-19 vaccines, including innate immunity, trained innate immunity, and mucosal responses. It also discusses the inequality in access to vaccines and vaccine-related immunological research in Africa. The authors argue that strengthening immunology research in Africa can provide insights into fundamental aspects of vaccination, including the relevance of genetics, trained innate immunity, and microbiome diversity.

TRENDS IN IMMUNOLOGY (2023)

Article Immunology

COVID-19 vaccination refusal trends in Kenya over 2021

Ryan T. Rego et al.

Summary: A study in Kenya found that the vaccine refusal rate decreased from 24% in February 2021 to 9% in October 2021. Factors associated with refusal included higher education, living with someone with COVID-19 symptoms, having COVID-19 symptoms, and distrust in the government. The study highlights the need to target groups with specific characteristics to reduce vaccine refusal and improve equity.

VACCINE (2023)

Article Public, Environmental & Occupational Health

The impact of delayed access to COVID-19 vaccines in low- and lower-middle-income countries

Brenice Duroseau et al.

Summary: Despite the rapid development of COVID-19 vaccines, most low-income and lower-middle-income countries failed to achieve a population coverage of at least 10% during initial vaccine rollouts. Delayed access to vaccines was associated with increased cumulative cases and mortality, with smaller economies experiencing longer delays. This emphasizes the importance of equitable and timely access to vaccines for all countries, regardless of economic size.

FRONTIERS IN PUBLIC HEALTH (2023)

Review Public, Environmental & Occupational Health

Access to COVID-19 vaccines and testing in Africa: the importance of COVAX-Nigeria as a case study

Rafaella Fortini Queiroz Grenfell et al.

Summary: Since the pandemic declaration, it has become evident that countries with economic challenges and limited health resources are particularly vulnerable. The appearance of the Omicron variant has once again tested this vulnerability. Efforts to develop effective and affordable vaccines have been made, but there is a need for global availability and equitable distribution to contain the virus and advance public health. This report highlights the difficulties in accessing vaccines and diagnostics in sub-Saharan Africa compared to higher income countries.

PATHOGENS AND GLOBAL HEALTH (2023)

Article Medicine, General & Internal

Assessing the impacts of COVID-19 vaccination programme's timing and speed on health benefits, cost-effectiveness, and relative affordability in 27 African countries

Yang Liu et al.

Summary: The impact of vaccination programme timing was assessed using an epidemiological and economic model. It was found that early start dates for vaccination programmes yield the most health benefits and lowest incremental cost-effectiveness ratios (ICERs). However, late start dates in 2021 may still generate low ICERs and manageable affordability measures.

BMC MEDICINE (2023)

Article Public, Environmental & Occupational Health

Community dialogue meetings among district leaders improved their willingness to receive COVID-19 vaccines in Western Uganda, May 2021

Edirisa Juniour Nsubuga et al.

Summary: A study in Uganda found that public vaccine uptake is influenced by leaders' vaccine uptake. Baylor Uganda conducted dialogue meetings with district leaders from Western Uganda to promote vaccine uptake. Pre- and post-meeting questionnaires revealed that the meetings increased leaders' risk perception, reduced concerns, and improved their perception of vaccine benefits, access, and willingness to receive the vaccine.

BMC PUBLIC HEALTH (2023)

Article Multidisciplinary Sciences

Global inequity creates local insufficiency: A qualitative study of COVID-19 vaccine implementation challenges in low-and-middle-income countries

Victoria Haldane et al.

Summary: The COVID-19 pandemic has posed challenges to health promotion and care worldwide, especially in low- and middle-income countries (LMICs). This qualitative study examines perspectives from individuals living and working in LMICs on the challenges of implementing COVID-19 vaccine programs. Through thematic content analysis, the study identifies various challenges in vaccine program implementation, including issues related to equity, governance, regulation, logistics, and service delivery. The findings emphasize the importance of focusing on safe and sustainable service delivery, strengthening end-to-end vaccine delivery systems, and promoting vaccine equity during novel infectious disease outbreaks.

PLOS ONE (2023)

Article Immunology

Examining confidence and hesitancy towards COVID-19 vaccines: A cross-sectional survey using in-person data collection in rural Ghana

O. K. Afreh et al.

Summary: Vaccine hesitancy and confidence in Nkwanta South, Ghana were assessed in this study. Among the unvaccinated population, 30.6% displayed hesitancy, with common reasons including perceived lack of need, safety concerns, side effects, and lack of information. The findings can inform targeted health promotion strategies to increase vaccine uptake.

VACCINE (2023)

Article Multidisciplinary Sciences

Estimating the impact of COVID-19 vaccine inequities: a modeling study

Nicolo Gozzi et al.

Summary: Global COVID-19 vaccine distribution has been inequitable, leading to significant disparities in access. A study using mathematical modelling estimates that over 50% of deaths in selected low and lower-middle-income countries could have been prevented if vaccines had been more widely available early on. Even with similar access to vaccines as high-income countries, a considerable proportion of deaths could still have been averted. Lack of vaccine availability would require additional non-pharmaceutical interventions to reduce transmission.

NATURE COMMUNICATIONS (2023)

Article Public, Environmental & Occupational Health

Factors associated with COVID-19 vaccine hesitancy among healthcare workers in Cameroon and Nigeria: a web-based cross-sectional study

Jerry Brown Aseneh et al.

Summary: This study investigated the determinants of COVID-19 vaccine hesitancy among healthcare workers in Cameroon and Nigeria. The study found that mistrust in the vaccine, lower perception of the vaccine's importance on personal health, concerns about vaccine-related adverse effects, and uncertainty about colleagues' vaccine acceptability were associated with higher vaccine hesitancy. On the other hand, participants with chronic diseases and higher levels of concerns about COVID-19 were less likely to be hesitant to receive the vaccine.

INTERNATIONAL HEALTH (2023)

Article Public, Environmental & Occupational Health

COVID-19 vaccine inequity in African low-income countries

Chifundo Annessia Kunyenje et al.

Summary: Equitable access to COVID-19 vaccines is crucial for ending the pandemic. Disparities in vaccine coverage exist both among low-income and high-income countries, mainly due to limited supply, unequal distribution, production constraints in low-income countries, weak health systems, vaccine hesitancy, and misconceptions. To address this inequity, efforts should focus on expanding COVAX, waiving intellectual property rights, technology transfer, and conducting mass vaccination campaigns.

FRONTIERS IN PUBLIC HEALTH (2023)

Article Infectious Diseases

Knowledge, attitude and acceptability of COVID-19 vaccine among residents in rural communities in Ghana: a multi-regional study

Seth Amponsah-Tabi et al.

Summary: This study assessed the knowledge, attitude, and acceptability of the COVID-19 vaccine among residents in rural communities in Ghana. The results showed that more than half of the participants had inadequate knowledge, poor attitudes, and negative perceptions about the vaccine. The study found that the acceptability of the COVID-19 vaccine was low among rural residents in Ghana and highlighted the need for education and promotion to improve vaccination rates.

BMC INFECTIOUS DISEASES (2023)

Article Public, Environmental & Occupational Health

Acceptance of COVID-19 vaccine among sub-Saharan Africans (SSA): a comparative study of residents and diasporan dwellers

Chundung Asabe Miner et al.

Summary: This study compared the acceptance, resistance, and hesitancy of the COVID-19 vaccine between local residents and diasporan dwellers in sub-Saharan Africa. The uptake of the vaccine was 14.2% among locals and 25.3% among diasporans. Factors such as sex, education, occupation, and working status were associated with vaccine resistance among locals, while health care workers had higher vaccine hesitancy. Knowledge about COVID-19 vaccines affected acceptance, resistance, and hesitancy.

BMC PUBLIC HEALTH (2023)

Article Public, Environmental & Occupational Health

Inequality in COVID-19 vaccination in Africa

Saad Zbiri et al.

Summary: This study examined the distribution and determinants of COVID-19 vaccination in Africa from March 2021 to June 2022. It found that although some African countries have access to COVID-19 vaccines, not all have successfully vaccinated their populations. Analyzing reliable open-access data, the study revealed high inequalities in COVID-19 vaccination across African countries.

JOURNAL OF PUBLIC HEALTH IN AFRICA (2023)

Article Immunology

COVID-19 vaccine hesitancy among health workers in rural Uganda: A mixed methods study

Patrick Diox Ouni et al.

Summary: This study examined vaccine hesitancy among health workers in Dokolo district, northern Uganda. The results showed that 13.3% of the 346 health workers surveyed were hesitant to take the COVID-19 vaccine. Reasons for hesitancy included fear of side effects and lack of trust in the information provided by health authorities.

VACCINE: X (2023)

Review Immunology

Determinants of COVID-19 Vaccination Decision-Making Behaviors among Pregnant Women in Sub-Saharan Africa: A Scoping Review

Sylvia Ayieko et al.

Summary: Despite low uptake among pregnant women in Sub-Saharan Africa, this scoping review found that knowledge and attitudes were critical factors influencing COVID-19 vaccination decision-making. The prevalence of COVID-19 vaccine uptake during pregnancy was low (14.4-28%). Future studies should include theory-informed research and measure additional psychosocial factors and contextual constructs to improve maternal vaccination in Sub-Saharan Africa.

VACCINES (2023)

Article Immunology

Community-Based Approaches to Increase COVID-19 Vaccine Uptake and Demand: Lessons Learned from Four UNICEF-Supported Interventions

Kathryn L. Hopkins et al.

Summary: Vaccination is crucial in reducing the severity of COVID-19 and preventing deaths, but vaccine uptake varies greatly among different communities. This article discusses four UNICEF interventions in Zambia, Iraq, Ghana, and India that aimed to increase acceptance and demand for COVID-19 vaccines. The lessons learned include the importance of community engagement, tailored recommendations, human-centered design, and risk communication to improve vaccination rates.

VACCINES (2023)

Review Medicine, Research & Experimental

Vaccine Hesitancy in Sub-Saharan Africa in the Context of COVID-19 Vaccination Exercise: A Systematic Review

Elizabeth A. A. Ochola

Summary: This paper identifies 67 publications that analyze vaccine hesitancy in sub-Saharan Africa, highlighting the colonial backdrop of inequities in global health research, social-cultural complexities, poor community involvement, and public distrust as contributing factors. It emphasizes the importance of improving information exchange between healthcare professionals and citizens to encourage transparent vaccine information disclosure during delivery.

DISEASES (2023)

Article Communication

A qualitative inquiry in understanding trusted media sources to reduce vaccine hesitancy among Kenyans

Berhaun Fesshaye et al.

Summary: The COVID-19 vaccine rollout in Kenya faces challenges in terms of vaccine supply and demand. Vaccine hesitancy among a third of the adult population is a barrier to reaching vaccination targets. Pregnant and lactating women have low uptake rates, possibly due to misinformation and uncertainty amplified by the media. This study explores the relationship between the media and vaccine decision-making among various groups in Kenya, emphasizing the importance of accurate and accessible information to reduce hesitancy and achieve vaccination goals.

FRONTIERS IN COMMUNICATION (2023)

Review Health Care Sciences & Services

Factors influencing the prioritization of vaccines by policymakers in low- and middle-income countries: a scoping review

Dominique Guillaume et al.

Summary: Decision-making for vaccine introduction in LMICs is influenced by factors such as disease burden, vaccine price, affordability, and communication. This scoping review identified two additional criteria: communication and sociocultural considerations.

HEALTH POLICY AND PLANNING (2023)

Article Public, Environmental & Occupational Health

Redressing COVID-19 vaccine inequity amidst booster doses: charting a bold path for global health solidarity, together

Sudhan Rackimuthu et al.

Summary: Global vaccine inequity poses risks to the health of the global population and exacerbates socio-economic repercussions, particularly in low- and middle-income countries. Various strategies, such as Intellectual Property waivers, increased donations, and the establishment of new vaccine manufacturing hubs, can be employed to achieve global immunization goals. Continued advocacy for vaccine equity by all stakeholders and critical amendments to existing or upcoming legislation and funding mechanisms will address the shortcomings of current inequitable vaccine distribution.

GLOBALIZATION AND HEALTH (2022)

Article Public, Environmental & Occupational Health

Vaccine anxieties, vaccine preparedness: Perspectives from Africa in a Covid-19 era

Melissa Leach et al.

Summary: This article explores the socio-political contexts and intersections between supply and demand of vaccines in African settings, using a framework of "vaccine anxieties". By considering the socially-embedded reasons for people's desire or reluctance for COVID-19 vaccines, as well as the dynamics of vaccine supply, access, and distribution, the article provides new insights into debates about vaccine confidence and preparedness. It highlights the importance of understanding the African context and social situations that are often overlooked in vaccine discussions.

SOCIAL SCIENCE & MEDICINE (2022)

Editorial Material Public, Environmental & Occupational Health

COVID-19 vaccine hesitancy in Africa: a call to action

Polydor Ngoy Mutombo et al.

LANCET GLOBAL HEALTH (2022)

Article Obstetrics & Gynecology

Knowledge, attitudes, and practices of pregnant women regarding COVID-19 vaccination in pregnancy in 7 low- and middle-income countries: An observational trial from the Global Network for Women and Children's Health Research

Seemab Naqvi et al.

Summary: A survey conducted in seven low- and middle-income countries found that knowledge, attitudes, and practices regarding COVID-19 vaccination in pregnancy were generally low but varied. Increasing awareness about vaccine safety and effectiveness among pregnant women is essential to improve vaccination rates.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2022)

Article Multidisciplinary Sciences

Assessment of COVID-19 vaccine hesitancy among Zimbabweans: A rapid national survey

Paddington Tinashe Mundagowa et al.

Summary: About half of Zimbabweans are willing to be vaccinated against COVID-19, but the majority lack trust in the government and are uncertain about the effectiveness and safety of the vaccine. Policymakers should target geographical and demographic groups with vaccine information, education, and communication to improve vaccine uptake.

PLOS ONE (2022)

Article Public, Environmental & Occupational Health

COVAX, vaccine donations and the politics of global vaccine inequity

Antoine de Bengy Puyvallee et al.

Summary: This article critically analyzes the principles and practice of dose-sharing within COVAX, highlighting the political factors at play. Donated doses were an important source of COVAX's vaccine supply, but donor countries and the pharmaceutical industry pursued their own interests, undermining the impact of dose-sharing.

GLOBALIZATION AND HEALTH (2022)

Article Medicine, General & Internal

Factors influencing hesitancy towards adult and child COVID-19 vaccines in rural and urban West Africa: a cross-sectional study

Sylvain Landry B. Faye et al.

Summary: This study investigated adult and child COVID-19 vaccine hesitancy in five West African countries and found that television, radio, and social media are the main sources of vaccine information. The study also identified that perceived effectiveness and safety of COVID-19 vaccines can increase willingness to get vaccinated.

BMJ OPEN (2022)

Editorial Material Medicine, General & Internal

It is not too late to achieve global covid-19 vaccine equity

Gavin Yamey et al.

BMJ-BRITISH MEDICAL JOURNAL (2022)

Article Biotechnology & Applied Microbiology

Factors associated with COVID-19 vaccine hesitancy in Senegal: a mixed study

Mouhamadou Faly Ba et al.

Summary: This study conducted in Senegal used an explanatory, sequential, mixed-methods design to explore COVID-19 vaccine hesitancy and refusal. The findings revealed that factors associated with hesitancy and refusal were diverse and complex, including gender, urban residency, negative attitudes toward the vaccine, skepticism about its effectiveness, influence from important individuals, and lack of information from healthcare professionals. Addressing these factors is crucial for improving vaccination coverage.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2022)

Article Public, Environmental & Occupational Health

Global disparities in public health guidance for the use of COVID-19 vaccines in pregnancy

Eleonor Zavala et al.

Summary: This study tracks the development of policies on COVID-19 vaccine use in pregnancy across 224 countries and territories and reveals the evolution of these policies over a 5-month period in 2021. The study finds substantial global variation in public health guidance regarding COVID-19 vaccine use in pregnancy, with inequities in access persisting for pregnant people, particularly in low and middle income countries.

BMJ GLOBAL HEALTH (2022)

Review Medicine, General & Internal

Determinants of COVID-19 vaccine hesitancy and uptake in sub-Saharan Africa: a scoping review

Michael J. Deml et al.

Summary: This scoping review identified, described, and mapped the research tools used to measure COVID-19 vaccine hesitancy, refusal, acceptance, and access in sub-Saharan Africa (SSA). The findings revealed that while all studies measured COVID-19 vaccine hesitancy, acceptance, and refusal, relatively few studies explicitly measured access to COVID-19 vaccination. Therefore, future research should prioritize the inclusion of access-related variables, and the development of standardized research tools to operationalize and measure the complex determinants of vaccine uptake in SSA and other low- and middle-income country settings is recommended.

BMJ OPEN (2022)

Article Immunology

COVID-19 vaccinology landscape in Africa

Sara Baptista et al.

Summary: Africa continues to struggle in terms of COVID-19 vaccine distribution and faces challenges in vaccine development, deployment, and sustainability for other major infectious diseases. To address the ongoing vaccine shortage, Africa needs to diversify investments, improve vaccine acquisition capacity, and increase awareness about vaccines.

FRONTIERS IN IMMUNOLOGY (2022)

Review Immunology

Persisting Vaccine Hesitancy in Africa: The Whys, Global Public Health Consequences and Ways-Out-COVID-19 Vaccination Acceptance Rates as Case-in-Point

Emmanuel O. Njoga et al.

Summary: Vaccine hesitancy remains a challenge in Africa, with COVID-19 vaccine acceptance rates ranging from 21.0% to 97.9%. Southern and eastern African regions have higher acceptance rates compared to other regions. Factors contributing to vaccine hesitancy include global vaccine inequality, lack of vaccine production facilities, insecurity, illiteracy, corruption, mistrust in political leaders, and the spreading of unconfirmed anti-vaccination rumors. Low vaccine acceptance rates in Africa have implications for global public health, as it can contribute to the emergence and spread of SARS-CoV-2 variants of concern.

VACCINES (2022)

Article Immunology

COVID-19 vaccination in Africa: A case of unsatisfied expectation and ill-preparedness

Osmond C. Ekwebelem et al.

Summary: With a large population and limited resources, Africa faced challenges in distributing the COVID-19 vaccine. African governments were advised to coordinate resources and healthcare workers for a successful vaccination campaign. Despite slow progress, it is important to prioritize vaccination beyond frontline workers and high-risk populations in order to enhance effectiveness and coverage in Africa's mass vaccination program.

VACCINE: X (2022)

Article Immunology

Attitudes to Vaccine Mandates among Late Adopters of COVID-19 Vaccines in Zimbabwe

Azure Tariro Makadzange et al.

Summary: Despite sufficient vaccine supply, less than 25% of the population in sub-Saharan Africa has received a COVID-19 vaccine. This study surveyed individuals who were late-adopters of vaccination in Zimbabwe to understand their attitudes towards vaccine mandates and vaccines for children. The findings suggest that vaccine mandates can help mitigate vaccine hesitancy and increase vaccine coverage in Africa.

VACCINES (2022)

Article Law

ADDRESSING VACCINE INEQUITY DURING THE COVID-19 PANDEMIC: THE TRIPS INTELLECTUAL PROPERTY WAIVER PROPOSAL AND BEYOND

Siva Thambisetty et al.

Summary: This article examines the issue of global vaccine inequity during the COVID-19 pandemic, focusing on the role of intellectual property (IP) law in enabling the inequities in vaccine production, distribution, and pricing. The authors argue that the TRIPS waiver proposal should be seen as a necessary and proportionate legal measure to address IP barriers that cannot be resolved by existing TRIPS flexibilities. They also reflect on the wider context of TRIPS and the importance of enhancing global pandemic preparedness.

CAMBRIDGE LAW JOURNAL (2022)

Article Infectious Diseases

Worldwide vaccine inequality threatens to unleash the next COVID-19 variant

Richard L. Oehler et al.

Summary: The emergence of the Omicron variant resulted in a significant increase in COVID-19 cases in South Africa in November 2021, and it quickly became the dominant strain in Africa, Europe, and the United States. Variants originating from regions with low vaccination rates are a consequence of unchecked virus replication in unprotected populations. Global efforts are needed to address vaccine inequities and prevent the emergence of future devastating variants.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2022)

Article Multidisciplinary Sciences

COVID-19 vaccine acceptance and perceived risk among pregnant and non-pregnant adults in Cameroon, Africa

Nuwan Gunawardhana et al.

Summary: COVID-19 vaccine hesitancy and misinformation were prevalent among pregnant and non-pregnant adults in Cameroon in 2021. Lack of interest and doubts about vaccine efficacy and safety were common. Consistent public health messaging from medical professionals and local vaccine production are likely to improve vaccine acceptability.

PLOS ONE (2022)

Article Biotechnology & Applied Microbiology

Lack of clear national policy guidance on COVID-19 vaccines influences behaviors in pregnant and lactating women in Kenya

Eleonor Zavala et al.

Summary: This study conducted qualitative interviews with pregnant and lactating women (PLW), health workers, and policymakers in Kenya and found that policymakers and health workers were uncertain about the policy and lacked communication, leading to vaccine hesitancy among PLW. This could potentially exacerbate inequities in vaccine access.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2022)

Review Health Policy & Services

Understanding the policy dynamics of COVID-19 vaccination in Ghana through the lens of a policy analytical framework

Roger A. Atinga et al.

Summary: This article analyzes the issues and challenges of COVID-19 vaccination in Ghana, including political struggles, vaccine shortages, and vaccine hesitancy. The article suggests that scaling up vaccination requires political unity, cohesive frames, and addressing contextual factors that promote vaccine hesitancy.

HEALTH RESEARCH POLICY AND SYSTEMS (2022)

Article Public, Environmental & Occupational Health

COVID-19 vaccine hesitancy trends in Ghana: a cross- sectional study exploring the roles of political allegiance, misinformation beliefs, and sociodemographic factors

Ken Brackstone et al.

Summary: Hesitancy rates among unvaccinated individuals in Ghana continue to rise, with key reasons including lack of information and concerns about vaccine safety. Vaccine awareness strategies need to be customized for different subpopulations to address vaccine-related concerns and ensure high vaccine uptake in Ghana.

PAN AFRICAN MEDICAL JOURNAL (2022)

Review Public, Environmental & Occupational Health

COVID-19 vaccine hesitancy in Africa: a scoping review

Betty B. B. Ackah et al.

Summary: This study summarized the literature on COVID-19 vaccine hesitancy in Africa, finding fluctuating vaccine acceptance rates in African countries and identifying major reasons for hesitancy including concerns about vaccine safety, lack of trust in the pharmaceutical industry, and conflicting information from the media.

GLOBAL HEALTH RESEARCH AND POLICY (2022)

Article Multidisciplinary Sciences

COVID-19 vaccine hesitancy among medical and health science students attending Wolkite University in Ethiopia

Ayenew Mose et al.

Summary: This study found that the level of COVID-19 vaccine hesitancy among medical and health science students is 41.2%. Factors associated with vaccine hesitancy include age <= 23 years, being female, residing in rural areas, sourcing information from social media, and practicing good COVID-19 mitigation measures.

PLOS ONE (2022)

Article Public, Environmental & Occupational Health

Trust and willingness towards COVID-19 vaccine uptake: a mixed-method study in Ghana, 2021

Joshua Amo-Adjei et al.

Summary: Trust and willingness to take the COVID-19 vaccine are high among the priority population in Ghana. Trust in the effectiveness and safety of the vaccine, rather than socioeconomic characteristics, is a better predictor of acceptance. Mistrust in political actors, belief in God's protection, and misunderstanding of vaccine development processes hinder acceptance, while professional influence and past successes of vaccination programs enhance trust and acceptance. Strategic communication approaches should be used to address triggers of mistrust and enhance trust.

ARCHIVES OF PUBLIC HEALTH (2022)

Editorial Material Public, Environmental & Occupational Health

Addressing challenges to rolling out COVID-19 vaccines in African countries

Jean B. Nachega et al.

LANCET GLOBAL HEALTH (2021)

Article Immunology

Assessment of Vaccine Hesitancy to a COVID-19 Vaccine in Cameroonian Adults and Its Global Implication

Jerome Nyhalah Dinga et al.

Summary: This study aimed to assess vaccine hesitancy towards a COVID-19 vaccine in Cameroonians, revealing a hesitancy rate of 84.6%. The most prominent determinants observed were communication and media environment, perception of pharmaceutical industry, reliability and/or source of vaccine, and cost. The study highlights the need for addressing safety, efficacy, and confidence concerns through a public engagement approach for successful administration of a COVID-19 vaccine in Africa or specifically in Cameroon.

VACCINES (2021)

Editorial Material Medicine, Research & Experimental

COVID-19 Vaccine Diplomacy and Equitable Access to Vaccines Amid Ongoing Pandemic

Khan Sharun et al.

Summary: Wealthy countries have secured 60% of COVID-19 vaccine supplies, with some preordering enough doses to vaccinate their populations multiple times. India's Vaccine Maitri initiative aims to provide doses to low-income countries, emphasizing equitable access to vaccines is crucial for global vaccination coverage. Manufacturing affordable vaccines and exporting large consignments worldwide will help meet global vaccine needs.

ARCHIVES OF MEDICAL RESEARCH (2021)

Article Ethics

Out of Africa: A Solidarity-Based Approach to Vaccine Allocation

Nancy Jecker et al.

Summary: This article advocates a solidaristic approach to global vaccine distribution, emphasizing priority for low- and middle-income countries and high-risk populations. By examining the interaction of biosocial forces, it provides a theoretical basis for the formation of global health alliances.

HASTINGS CENTER REPORT (2021)

Article Health Care Sciences & Services

COVID-19 vaccine challenges: What have we learned so far and what remains to be done?

Rebecca Forman et al.

Summary: The development and distribution of a safe and effective SARS-CoV-2 (COVID-19) vaccine has attracted global interest. Despite emergency use authorization for several vaccine candidates within a year of the pandemic, there are still significant policy challenges that require a collaborative global response.

HEALTH POLICY (2021)

Editorial Material Virology

Equal access of COVID-19 vaccine distribution in Africa: Challenges and way forward

Abdullahi T. Aborode et al.

Summary: The WHO and Africa CDC in Africa are calling for the international community and countries in Africa to ensure equal access to COVID-19 vaccines, addressing issues related to poverty and other negative factors that hinder fair distribution. The African Union has endorsed the need for Africa to actively engage in easy accessibility to COVID-19 vaccines to strengthen local distribution systems and workforce skills.

JOURNAL OF MEDICAL VIROLOGY (2021)

Editorial Material Medicine, General & Internal

COVID-19 vaccine impact in Israel and a way out of the pandemic

Eyal Leshem et al.

LANCET (2021)

Article Public, Environmental & Occupational Health

Tracking the uptake and trajectory of COVID-19 vaccination coverage in 15 West African countries: an interim analysis

Muhammed Olanrewaju Afolabi et al.

Summary: The article discusses the COVID-19 vaccination uptake trends in the ECOWAS region, highlighting the need to significantly increase the vaccination speed to achieve the target coverage of 60% within the specified time frame. It emphasizes the importance for West African governments to implement effective strategies to improve vaccination speed and coverage.

BMJ GLOBAL HEALTH (2021)

Editorial Material Microbiology

Global COVID-19 vaccine inequity: The scope, the impact, and the challenges

Archana Asundi et al.

Summary: Global vaccine inequity is prolonging the COVID-19 pandemic. Challenges in vaccine development, manufacturing, and distribution need to be addressed to resolve this crisis.

CELL HOST & MICROBE (2021)

Editorial Material Immunology

COVID-19 vaccine access in Africa: Global distribution, vaccine platforms, and challenges ahead

Marguerite Massinga Loembe et al.

Summary: The development of COVID-19 vaccines at a record pace is a remarkable global scientific achievement, but equitable access to vaccines remains a challenge. African countries must take action to ensure vaccination of their populations and ultimately overcome the pandemic.

IMMUNITY (2021)

Editorial Material Biochemistry & Molecular Biology

Understanding COVID-19 vaccine hesitancy

Shingai Machingaidze et al.

Summary: The new study reveals the complexities of COVID-19 vaccine hesitancy and acceptance in low-, middle-, and high-income countries.

NATURE MEDICINE (2021)

Article Biotechnology & Applied Microbiology

Participating in a vaccine trial for COVID-19 in Senegal: trust and information

V Ridde et al.

Summary: The willingness of Senegalese people to participate in a COVID-19 vaccine trial is not high, with females showing a higher intention. Those who are willing to receive the COVID-19 vaccine and believe that getting infected with the coronavirus would have a significant impact on their health are more likely to agree to participate. Confidence in the vaccine, health personnel, and government plays a crucial role in determining participants' willingness to join the vaccine trial.

HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)

Article Immunology

Examining Vaccine Hesitancy in Sub-Saharan Africa: A Survey of the Knowledge and Attitudes among Adults to Receive COVID-19 Vaccines in Ghana

Theophilus Acheampong et al.

Summary: In Ghana, about half of urban adult residents are willing to take the COVID-19 vaccine, while approximately one-fifth are unlikely to do so, and another 28% are undecided. Vaccine hesitancy varies across socio-demographic characteristics such as age, gender, and primary sources of information. Achieving herd immunity in Ghana will require combining preventive vaccination programs with a robust public education campaign addressing misconceptions about vaccines.

VACCINES (2021)

Article Immunology

Disparities in COVID-19 Vaccination among Low-, Middle-, and High-Income Countries: The Mediating Role of Vaccination Policy

Yuqi Duan et al.

Summary: The study found that there is inequality in COVID-19 vaccine coverage among countries with different income levels, with lower-income countries having lower coverage rates. Vaccination policies have varying effects on coverage rates in different income groups. The main cause of vaccine inequality is income disparity, and vaccine nationalism hinders the functioning of the global vaccine allocation framework.

VACCINES (2021)

Article Public, Environmental & Occupational Health

COVID-19 Vaccination in Lower-Middle Income Countries: National Stakeholder Views on Challenges, Barriers, and Potential Solutions

Eunice Twumwaa Tagoe et al.

Summary: The development of COVID-19 vaccines does not mean the end of the pandemic, as countries need to purchase enough doses and successfully roll out vaccination plans. Low- and middle-income countries may encounter more challenges in vaccine distribution, but with strategies to overcome barriers and expand vaccination programs, successful rollout can be achieved.

FRONTIERS IN PUBLIC HEALTH (2021)

Review Infectious Diseases

The challenges to a successful COVID-19 vaccination programme in Africa

Israel Oluwasegun Ayenigbara et al.

Summary: African countries have faced challenges in their COVID-19 vaccination rollout, including delays, limited funds, safety concerns, storage requirements, limited shelf life, and difficulties accessing vulnerable communities. Solutions and recommendations have been provided to optimize the vaccination program and ensure success in Africa.
Article Infectious Diseases

COVID-19 vaccine hesitancy among staff and students in a Nigerian tertiary educational institution

Ikemefuna Chijioke Uzochukwu et al.

Summary: Only about 34.70% of the Nnamdi Azikiwe University community are willing to receive the COVID-19 vaccine, with a high hesitancy rate of 65.04%. Marital status, age, and christian denominational affiliation significantly influence respondents' perception of COVID-19 vaccination, while factors such as gender, occupation, previous vaccination experience, awareness of COVID-19, and previous symptoms of COVID-19 do not significantly affect respondents' willingness to be vaccinated.

THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE (2021)

Review Medicine, General & Internal

Global access to COVID-19 vaccines: a scoping review of factors that may influence equitable access for low and middle-income countries

Elizabeth F. Peacocke et al.

Summary: This study aimed to identify factors affecting equitable access to COVID-19 vaccines for low and middle-income countries, finding four key factors such as collectively agreed global mechanisms, vaccine manufacturing, and countries' strength in implementing vaccination programs.

BMJ OPEN (2021)

Review Public, Environmental & Occupational Health

COVID-19 Pandemic Worsening Gender Inequalities for Women and Girls in Sub-Saharan Africa

Bright Opoku Ahinkorah et al.

Summary: Pandemics like COVID-19 often result in crises at international, national, and sub-regional levels, exacerbating existing inequalities. In sub-Saharan Africa, the pandemic has disproportionately affected girls and women in various aspects such as health, education, and work. Policy actions are needed to address the complex disparities and mitigate the burden faced by women in the region.

FRONTIERS IN GLOBAL WOMENS HEALTH (2021)

Article Public, Environmental & Occupational Health

Dealing with vaccine hesitancy in Africa: the prospective COVID-19 vaccine context

Aanuoluwapo Adeyimika Afolabi et al.

Summary: In order to enhance the acceptance of COVID-19 vaccines, it is necessary to promote community involvement, improve feedback mechanisms, strengthen multi-sectoral collaboration, and integrate the vaccine into routine immunization programs.

PAN AFRICAN MEDICAL JOURNAL (2021)

Article Public, Environmental & Occupational Health

Misinformation About COVID-19 in Sub-Saharan Africa: Evidence from a Cross-Sectional Survey

Uchechukwu L. Osuagwu et al.

Summary: The study found a high prevalence of misinformation about COVID-19 in sub-Saharan Africa. Those who believed that COVID-19 was unlikely to continue in their countries were more likely to believe in false statements. Other significant factors associated with belief in misinformation included age, employment status, gender, education level, and knowledge about the main clinical symptoms of COVID-19.

HEALTH SECURITY (2021)

Editorial Material Multidisciplinary Sciences

COVID-19 vaccines: how to ensure Africa has access

John N. Nkengasong et al.

NATURE (2020)