期刊
MODERN RHEUMATOLOGY CASE REPORTS
卷 -, 期 -, 页码 -出版社
OXFORD UNIV PRESS
DOI: 10.1093/mrcr/rxad068
关键词
Kikuchi-Fujimoto disease; mesenteric lymph node; myositis; extranodal involvement
类别
Kikuchi-Fujimoto disease is a self-limiting disease characterized by fever and cervical lymphadenopathy. This article reports a rare case in which a patient with KFD developed muscle involvement and underwent mesenteric lymph node biopsy for diagnosis. The patient's body temperature gradually returned to normal and the muscle lesion resolved, indicating possible extranodal involvement.
Kikuchi-Fujimoto disease (KFD) is a self-limiting disease, characterised by fever and cervical lymphadenopathy. Lymphadenopathy without cervical lymph node involvement is rare and may mimic lymphoma. Although KFD can be associated with extranodal involvement, muscle involvement has not been reported. Herein, we report a novel case of unilateral gluteal myositis associated with mesenteric KFD in a patient who presented with persistent fever and right hip pain. Radiological imaging revealed an inflammatory lesion on the right gluteal muscle and multiple enlarged abdominal lymph nodes. No cervical lymphadenopathy was observed. A mesenteric lymph node biopsy was performed, and the histopathological findings led to a diagnosis of KFD. By day 29, the patient's body temperature gradually returned to normal without any therapeutic intervention. Follow-up radiological imaging showed resolution of the gluteal lesion and a significant decrease in abdominal lymph node size. Considering the clinical course, the unilateral myositis may have developed as an extranodal involvement of KFD. Even if the clinical findings appear unrelated to those of KFD, a differential diagnosis that includes KFD should be considered in patients with unknown origin of fever.
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