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Ronald B. Postuma et al.
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Highly sensitive amyloid detection enabled by thioflavin T dimers
Luoheng Qin et al.
MOLECULAR BIOSYSTEMS (2010)
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Katrin Beyer et al.
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L Ye et al.
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Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on β-amyloid peptide fibrils
A Lockhart et al.
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Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
AT Petkova et al.
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Stages in the development of Parkinson's disease-related pathology
H Braak et al.
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Dependence of α-synuclein aggregate morphology on solution conditions
W Hoyer et al.
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Oligomeric and fibrillar species of amyloid-β peptides differentially affect neuronal viability
KN Dahlgren et al.
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Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates
ZP Zhuang et al.
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