4.4 Review

Diagnosis and management of facial nerve palsy secondary to granulomatosis with polyangiitis - A systematic review

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Summary: This study presented 6 cases of facial nerve palsy and masked mastoiditis as revelators of localized GPA, evaluating the utility of ACR/EULAR 2017 criteria. Patients exhibited unilateral facial nerve palsy and hearing loss, with some showing rapid progression of the disease. The importance of early diagnosis and treatment for a better prognosis was highlighted.

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Summary: Granulomatosis with polyangiitis (GPA) is a necrotising vasculitis with unknown cause, typically involving acute inflammation of the respiratory tract and renal system, also potentially affecting the central nervous system. This case report presents a rare instance of GPA with facial nerve palsy as the initial manifestation.

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