☆ 4.7 Article

Radix Saposhnikoviae enhancing Huangqi Chifeng Decoction improves lipid metabolism in AS mice

JOURNAL OF ETHNOPHARMACOLOGY (2024)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Plant Sciences

Effects of modified Huangqi Chifeng decoction on the IL-17 signaling pathway in an IgA nephropathy rat model

Sijia Ma et al.

Summary: Based on animal experiments, this study found that the modified Huangqi Chifeng decoction (MHCD) has therapeutic effects on immunoglobulin A nephropathy (IgAN), including reducing urine protein levels, improving renal pathological injury, and reducing inflammation levels. This finding contributes to further understanding the mechanism of action of MHCD for IgAN treatment.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

添加到收藏夹

Review Endocrinology & Metabolism

Efficacy evaluation, active ingredients, and multitarget exploration of herbal medicine

Jun-ling Ren et al.

Summary: Evidence suggests that herbal medicine (HM) has potential benefits for treating diseases. However, the complexity of HM due to unclear bio-active compounds, mechanisms of action, undetermined therapy targets, and nonspecific features for metabolism, poses challenges for drug discovery. Metabolomics, particularly chinmedomics-based metabolomics, could be a useful tool for understanding the metabolism of HM, including its pathways, curative effects, mechanisms, active ingredients, and precision medicine.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2023)

添加到收藏夹

Article Cell Biology

iPLA2 inhibition blocks LysoPC-induced TRPC6 externalization and promotes Re-endothelialization of carotid injuries in hypercholesterolemic mice

Priya Putta et al.

Summary: Lipid oxidation products, such as lysophosphatidylcholine (lysoPC), hinder re-endothelization after vascular interventions by activating TRPC6 channels and inducing dysregulation of EC cytoskeleton. Inhibition of iPLA2 by FKGK11 prevents lysoPC-induced TRPC6 externalization, attenuates calcium influx, and partially preserves EC migration, promoting EC healing in cardiovascular patients undergoing angioplasty. FKGK11 also promotes re-endothelization in a carotid injury mouse model.

CELL CALCIUM (2023)

添加到收藏夹

Article Environmental Sciences

Metabolome-wide association study of four groups of persistent organic pollutants and abnormal blood lipids

Yiran Chen et al.

Summary: Environmental exposure increases the risk of dyslipidemia. Persistent organic pollutants (POPs), including PFASs, are associated with abnormal blood lipid levels. This study investigates the biomarkers mediating the relationships between blood lipids and POPs, revealing potential mechanisms.

ENVIRONMENT INTERNATIONAL (2023)

添加到收藏夹

Article Biochemical Research Methods

Research on the improvement effect of Saposhnikovia divaricata (Trucz.) Schischk on rheumatoid arthritis based on the association

Chang -Le Liu et al.

Summary: This study investigates the therapeutic effect and mechanism of Saposhnikovia divaricata in rats with rheumatoid arthritis. Saposhnikovia divaricata administration improves arthritis symptoms by downregulating ADA mRNA expression levels in the purine metabolic signaling pathway, mitigating foot swelling, improving the levels of serum inflammatory factors, and decreasing the ADA protein expression level.

ANALYTICAL BIOCHEMISTRY (2023)

添加到收藏夹

Article Food Science & Technology

Verbascoside exerts an anti-atherosclerotic effect by regulating liver glycerophospholipid metabolism

Peng Lei et al.

Summary: Verbascoside, abundant in olive mill wastewater, has been found to have anti-atherosclerotic effects by reducing plasma lipid levels and delaying arterial plaque formation in a mouse model. It also shows hepatoprotective effects by alleviating liver function markers. Furthermore, verbascoside stabilizes glycerophospholipid metabolism and modulates lipid metabolism disorders, leading to reduced lipid deposition in the liver.

FOOD SCIENCE AND HUMAN WELLNESS (2023)

添加到收藏夹

Review Chemistry, Multidisciplinary

Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review

Fan-Shun Zhang et al.

Summary: Colchicine is an ancient herbal drug with unique anti-inflammatory effects and prominent cardiovascular actions. Clinical trials have confirmed its curative effect in treating cardiovascular diseases, and its anti-inflammatory mechanisms have been studied.

ACTA PHARMACOLOGICA SINICA (2022)

添加到收藏夹

Article Plant Sciences

Study on the new anti-atherosclerosis activity of different Herba patriniae through down-regulating lysophosphatidylcholine of the glycerophospholipid metabolism pathway

Dan Su et al.

Summary: This study aimed to explore the new pharmacological effect of Herba patriniae against AS, find out the best origin and extraction part, and ultimately discovered that PVJEE has the potential to treat AS by altering glycerophospholipid metabolism pathway.

PHYTOMEDICINE (2022)

添加到收藏夹

Article Medicine, Research & Experimental

Spiraea prunifolia leaves extract inhibits adipogenesis and lipogenesis by promoting β-oxidation in high fat diet-induced obese mice

Ju-Hyoung Park et al.

Summary: Spiraea prunifolia has been traditionally used in Korean medicine for its anti-malaria, anti-fever, and anti-emetic effects. This study investigated the effects of Spiraea prunifolia leaves extract (SPE) on obesity using a high-fat diet-induced obese mouse model. The results showed that oral administration of SPE significantly reduced body weight, serum levels of cholesterol and triglycerides, adipose tissue weight, and adipocyte cell size. SPE also inhibited the expression of adipogenesis and lipogenesis related genes, while promoting beta-oxidation through AMP-activated protein kinase signaling. These findings demonstrate the anti-adipogenic, anti-lipogenic, and beta-oxidation effects of SPE in vivo.

BIOMEDICINE & PHARMACOTHERAPY (2022)

添加到收藏夹

Meeting Abstract Biochemistry & Molecular Biology

The Role of Fatty Acid Synthase in Atherosclerosis

Bethany Bogan et al.

FREE RADICAL BIOLOGY AND MEDICINE (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

The catalytic and structural basis of archaeal glycerophospholipid biosynthesis

Niels A. W. De Kok et al.

Summary: Archaeal glycerophospholipids, composed of isoprenyl chains ether-bonded to glycerol-1-phosphate, fundamentally differ from bacterial phospholipids. The chemical composition of archaeal membranes contributes to their survival in extreme environments. Understanding the structural basis of glycerophospholipid biosynthesis is crucial for insights into membrane formation evolution and extremophilicity.

EXTREMOPHILES (2022)

添加到收藏夹

Article Endocrinology & Metabolism

Integrated Bioinformatic Analysis of the Shared Molecular Mechanisms Between Osteoporosis and Atherosclerosis

Liang Mo et al.

Summary: This study explores the molecular mechanism between osteoporosis and atherosclerosis through bioinformatic analysis and identifies immune and inflammatory response as common features in their pathophysiology. Six hub genes are identified, and the role of has-let-7g in the common mechanisms is highlighted. These findings provide insights into shared molecular mechanisms and potential targets for further experimental studies.

FRONTIERS IN ENDOCRINOLOGY (2022)

添加到收藏夹

Article Biochemistry & Molecular Biology

The important role of glycerophospholipid metabolism in the protective effects of polyphenol-enriched Tartary buckwheat extract against alcoholic liver disease

Peng Cao et al.

Summary: This study found that Tartary buckwheat extract can prevent alcoholic liver disease by modulating hepatic glycerophospholipid metabolism. Tartary buckwheat extract is able to alleviate liver injury and abnormal lipid levels, possibly through the regulation of energy metabolism-related genes and lipid synthesis-related genes.

FOOD & FUNCTION (2022)

添加到收藏夹

Review Geriatrics & Gerontology

Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy

Michael Tran Duong et al.

Summary: VCID is a common cause of cognitive decline, primarily caused by atherosclerosis leading to cerebrovascular disease and eventually neurodegeneration. Risk factors including hypercholesterolemia and hypertension promote atherosclerosis and carotid artery stenosis, disrupting cerebral blood flow and triggering ischemic strokes and VCID. The role of APOE, particularly APOE4, in lipid metabolism and chronic inflammation contributes to the pathogenesis of VCID.

FRONTIERS IN AGING NEUROSCIENCE (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

Bei Wang et al.

Summary: The arachidonic acid (AA) pathway is crucial in cardiovascular biology, carcinogenesis, and various inflammatory diseases, producing bioactive mediators that are potential targets for cardiovascular diseases, cancers, and inflammatory diseases. This review summarizes the physiological and pathophysiological importance of AA metabolizing pathways, as well as the molecular mechanisms underlying its actions in CVD and cancer progression. Additionally, clinical studies targeting AA metabolisms in different disease conditions are introduced to explore the role of AA metabolism and potential therapies.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

添加到收藏夹

Article Neurosciences

Effect of APOE Genotype on Plasma Docosahexaenoic Acid (DHA), Eicosapentaenoic Acid, Arachidonic Acid, and Hippocampal Volume in the Alzheimer's Disease Cooperative Study -Sponsored DHA Clinical Trial

Natalie Tomaszewski et al.

JOURNAL OF ALZHEIMERS DISEASE (2020)

添加到收藏夹

Article Pharmacology & Pharmacy

Quality Evaluation of &ITSaposhnikoviae Radix &IT(Differences between Wild-type and Cultivated Products)

Masakazu Nishihara et al.

YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN (2018)

添加到收藏夹

Review Pharmacology & Pharmacy

The leukotriene receptor antagonist montelukast and its possible role in the cardiovascular field

Malvina Hoxha et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2017)

添加到收藏夹

Article Biochemistry & Molecular Biology

Using UPLC-MS/MS for Characterization of Active Components in Extracts of Yupingfeng and Application to a Comparative Pharmacokinetic Study in Rat Plasma after Oral Administration

Meng-Qi Jia et al.

MOLECULES (2017)

添加到收藏夹

Review Biochemistry & Molecular Biology

Adiponectin, lipids and atherosclerosis

Niki Katsiki et al.

CURRENT OPINION IN LIPIDOLOGY (2017)

添加到收藏夹

Review Cell Biology

AMPK signalling in health and disease

David Carling

CURRENT OPINION IN CELL BIOLOGY (2017)

添加到收藏夹

Article Veterinary Sciences

Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model

Ning Ma et al.

BMC VETERINARY RESEARCH (2016)

添加到收藏夹

Review Cell Biology

Transcriptional regulation of hepatic lipogenesis

Yuhui Wang et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)

添加到收藏夹

Editorial Material Biochemistry & Molecular Biology

Lipids in metabolic diseases

Isabelle Dugail et al.

BIOCHIMIE (2014)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Mediating lipid biosynthesis: Implications for cardiovascular disease

Xiaoli et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2013)

添加到收藏夹

Review Cardiac & Cardiovascular Systems

Molecular and cellular mechanisms of macrophage survival in atherosclerosis

Wim Martinet et al.

BASIC RESEARCH IN CARDIOLOGY (2012)

添加到收藏夹

Review Biochemistry & Molecular Biology

Phosphatidylcholine biosynthesis and lipoprotein metabolism

Laura K. Cole et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

添加到收藏夹

Review Plant Sciences

Compatibility art of traditional Chinese medicine: From the perspective of herb pairs

Shengpeng Wang et al.

JOURNAL OF ETHNOPHARMACOLOGY (2012)

添加到收藏夹

Review Plant Sciences

Omic techniques in systems biology approaches to traditional Chinese medicine research: Present and future

Alessandro Buriani et al.

JOURNAL OF ETHNOPHARMACOLOGY (2012)

添加到收藏夹

Review Chemistry, Medicinal

Potential Role of Metabolomic Approaches for Chinese Medicine Syndromes and Herbal Medicine

Hui Sun et al.

PHYTOTHERAPY RESEARCH (2012)

添加到收藏夹

Review Cell Biology

Protective effects of AMP-activated protein kinase in the cardiovascular system

Qiang Xu et al.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2010)

添加到收藏夹

Article Medicine, Research & Experimental

被撤回的出版物: Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice (Retracted article. See vol. 122, pg. 1131, 2012)

Fei Wang et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

添加到收藏夹

Article Peripheral Vascular Disease

Acute effects of lipid apheresis on human serum lipidome

Sergey Tselmin et al.

ATHEROSCLEROSIS SUPPLEMENTS (2009)

添加到收藏夹

Article Multidisciplinary Sciences

Prostaglandin F2α elevates blood pressure and promotes atherosclerosis

Ying Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

添加到收藏夹

Article Biochemistry & Molecular Biology

Urinary prostaglandin F2α is generated from the isoprostane pathway and not the cyclooxygenase in humans

Huiyong Yin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

添加到收藏夹

Article Biochemistry & Molecular Biology

Regulation of acetyl-CoA carboxylase

RW Brownsey et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2006)

添加到收藏夹

Review Pharmacology & Pharmacy

Cyclooxygenase-2 and inflammation in atherosclerosis

MF Linton et al.

CURRENT OPINION IN PHARMACOLOGY (2004)

添加到收藏夹

Review Biochemistry & Molecular Biology

Lipids and atherosclerosis

PC Choy et al.

BIOCHEMISTRY AND CELL BIOLOGY (2004)

添加到收藏夹

Article Hematology

Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein

TS Worgall et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)

添加到收藏夹

Article Biochemistry & Molecular Biology

Dietary soybean phosphatidylcholines lower lipidemia: Mechanisms at the levels of intestine, endothelial cell, and hepato-biliary axis

I Mastellone et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.