期刊
Journal of Applied Biomaterials & Functional Materials
卷 14, 期 3, 页码 E296-E301出版社
WICHTIG PUBLISHING
DOI: 10.5301/jabfm.5000271
关键词
Antimicrobial efficacy; Bioactive glass; Biofilm; Mechanical properties; Resin composite
Background: The aim of this study was to evaluate the antimicrobial efficacy and mechanical properties of dental resin composites containing different amounts of microparticulate bioactive glass (BAG). Methods: Experimental resin composites were prepared by mixing resin matrix (70% BisGMA and 30% TEG-DMA) and inorganic filler with various fractions of BAG to achieve final BAG concentrations of 5, 10 and 30 wt%. Antimicrobial efficacy was assessed in aqueous suspension against Escherichia coli, Staphylococcus aureus and Streptococcus mutans and in biofilm against S. mutans. The effect of incorporation of BAG on the mechanical properties of resin composite was evaluated by measuring the surface roughness, compressive strength and flexural strength. Results: Under the dynamic contact condition, viable counts of E. coli, S. aureus and S. mutans in suspensions were reduced up to 78%, 57% and 50%, respectively, after 90 minutes of exposure to disc-shaped composite specimens, depending on the BAG contents. In 2-day-old S. mutans biofilm, incorporation of BAG into composite at ratios of 10% and 30% resulted in 0.8 and 1.4 log reductions in the viable cell counts compared with the BAG-free composite, respectively. The surface roughness values of composite specimens did not show any significant difference (p>0.05) at any concentration of BAG. However, compressive and flexural strengths of composite were decreased significantly with addition of 30% BAG (p<0.05). Conclusions: The results demonstrated the successful utilization of BAG as a promising biomaterial in resin composites to provide antimicrobial function.
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