Role of site selective substitution, magnetic parameter tuning, and self heating in magnetic hyperthermia application: Eu-doped magnetite nanoparticles

Various researchers have provided considerable insight into the fundamental mechanisms behind the power absorption of single-domain magnetic nanoparticles (MNPs) in magnetic hyperthermia applications. However, the role of all parameters pertinent to magnetic relaxation continues to be debated. Herein, to explore the role of magnetic anisotropy with the site selective substitution related to magnetic relaxation has generally been missing, which is critically essential in respective of hyperthermia treatment. Our study unravels contradictory results of rare earth (RE) interaction effects in ferrite to that of recently reported literature. Despite this, rare earth atoms have unique f-block properties, which significantly impact the magnetic anisotropy as well as the relaxation mechanism. Here, we use appropriate Eu doping concentration in magnetite and analyze its effect on the matrix. Furthermore, a positive SAR can effectively reduce the relative dose assigned to a patient to a minimal level. This study indicates that the introduction of Eu ion positively influenced the heating efficiency of the examined magnetite systems.

Automated summary

Researchers have gained considerable insight into the power absorption mechanisms of single-domain magnetic nanoparticles (MNPs) in magnetic hyperthermia applications. However, the role of magnetic relaxation parameters is still debated. This study explores the role of magnetic anisotropy and site selective substitution in magnetic relaxation, emphasizing the importance in hyperthermia treatment. Additionally, the introduction of Eu ion positively influenced the heating efficiency of magnetite systems, indicating a potential for improved hyperthermia therapy.