期刊
CLINICS IN LIVER DISEASE
卷 19, 期 2, 页码 309-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cld.2015.01.005
关键词
Hepatocellular carcinoma; Alpha-fetoprotein; Chronic hepatitis C virus infection; Chronic hepatitis B virus infection; Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein; Des-gamma-carboxy prothrombin
The incidence of cirrhosis-related hepatocellular carcinoma (HCC) is rising. Curative surgical options are available; outcomes are acceptable with early diagnosis. Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3) and des-gamma-carboxy prothrombin (DCP) are HCC risk markers. A high or increasing serum biomarker level can be predictive of the eventual development of HCC, large tumor size, advanced stage, extrahepatic metastases, portal vein thrombosis, and postoperative HCC recurrence. Based on FDA guidelines for HOC risk assessment, clinicians can consider using either the combination of AFP-L3 with DCP, or the combination of AFP-L3 with AFP and DCP.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据