相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Regulation of redox signaling in HIF-1-dependent tumor angiogenesis
Valeria Manuelli et al.
FEBS JOURNAL (2022)
Regulation of glycolysis by the hypoxia-inducible factor (HIF): implications for cellular physiology
S. J. Kierans et al.
JOURNAL OF PHYSIOLOGY-LONDON (2021)
Hypoxia and hypoxia-inducible factors in diabetes and its complications
Sergiu-Bogdan Catrina et al.
DIABETOLOGIA (2021)
Cancer Cell Metabolism in Hypoxia: Role of HIF-1 as Key Regulator and Therapeutic Target
Vittoria Infantino et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Understanding the Therapeutic Potential of Ascorbic Acid in the Battle to Overcome Cancer
Jurnal Reang et al.
BIOMOLECULES (2021)
Molecular landscape of head and neck cancer and implications for therapy
Camile S. Farah
ANNALS OF TRANSLATIONAL MEDICINE (2021)
Head and neck cancer: the role of anti-EGFR agents in the era of immunotherapy
Morena Fasano et al.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY (2021)
NER-factor DDB2 regulates HIF1α and hypoxia-response genes in HNSCC
Prashant Bommi et al.
ONCOGENE (2020)
NF-κB and Its Role in Checkpoint Control
Annika C. Betzler et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
The Multifaceted Output of c-Jun Biological Activity: Focus at the Junction of CD8 T Cell Activation and Exhaustion
Athanasios G. Papavassiliou et al.
CELLS (2020)
Dynamic regulation of epigenetic demethylation by oxygen availability and cellular redox
Nermina Lamadema et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Clinical update on head and neck cancer: molecular biology and ongoing challenges
Elham Alsahafi et al.
CELL DEATH & DISEASE (2019)
Mechanisms of hypoxia signalling: new implications for nephrology
Johannes Schoedel et al.
NATURE REVIEWS NEPHROLOGY (2019)
Diagnostic Tumor Markers in Head and Neck Squamous Cell Carcinoma (HNSCC) in the Clinical Setting
Panagiota Economopoulou et al.
FRONTIERS IN ONCOLOGY (2019)
PTEN Is Associated With Worse Local Control in Early Stage Supraglottic Laryngeal Cancer Treated With Radiotherapy
Leonie Bruine de Bruin et al.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY (2019)
Advances in Hypoxia-Inducible Factor Biology
Hani Choudhry et al.
CELL METABOLISM (2018)
The MAPK-activator protein-1 signaling regulates changes in lung tissue of rat exposed to hypobaric hypoxia
Mrinalini Singh et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Maintaining a Healthy Proteome during Oxidative Stress
Dana Reichmann et al.
MOLECULAR CELL (2018)
Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway
Peng Jin et al.
ONCOGENE (2018)
Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine
Rafael Radi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Head and neck squamous cell carcinoma: Genomics and emerging biomarkers for immunomodulatory cancer treatments
Benjamin Solomon et al.
SEMINARS IN CANCER BIOLOGY (2018)
The molecular landscape of head and neck cancer
C. Rene Leemans et al.
NATURE REVIEWS CANCER (2018)
Activator protein-1 (AP-1): a bridge between life and death in lung epithelial (A549) cells under hypoxia
Seema Yadav et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2017)
pVHL mediates K63-linked ubiquitination of IKKβ, leading to IKKβ inactivation
Yuxin Wang et al.
CANCER LETTERS (2016)
Role of TET enzymes in DNA methylation, development, and cancer
Kasper Dindler Rasmussen et al.
GENES & DEVELOPMENT (2016)
PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation
Ninel Azoitei et al.
MOLECULAR CANCER (2016)
Hypoxic control of metastasis
Erinn B. Rankin et al.
SCIENCE (2016)
Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate
Shahrzad Movafagh et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
hCLOCK Causes Rho-Kinase-Mediated Endothelial Dysfunction and NF-κB-Mediated Inflammatory Responses
Xiao Tang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Temporal regulation of HIF-1 and NF-κB in hypoxic hepatocarcinoma cells
Yuan Jiang et al.
ONCOTARGET (2015)
HIF-1α pathway: role, regulation and intervention for cancer therapy
Georgina N. Masoud et al.
ACTA PHARMACEUTICA SINICA B (2015)
In vitro study of normoxic epidermal growth factor receptor-induced hypoxia-inducible factor-1-alpha, vascular endothelial growth factor, and BNIP3 expression in head and neck squamous cell carcinoma cell lines: Implications for anti-epidermal growth factor receptor therapy
Pablo Secades et al.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK (2015)
Distinct Phenotypes of Human Prostate Cancer Cells Associate with Different Adaptation to Hypoxia and Pro-Inflammatory Gene Expression
Linda Ravenna et al.
PLOS ONE (2014)
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I
Peter Ellinghaus et al.
CANCER MEDICINE (2013)
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells
Claudia Calabrese et al.
CANCER & METABOLISM (2013)
Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc DISTINCT ROLES OF PHD2 AND PHD3 PROTEINS IN CONTROLLING HIF-1α ACTIVITY IN HYPOXIA
Nobuyuki Fujita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
S. Y. Nam et al.
BRITISH JOURNAL OF CANCER (2011)
Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain
Yukio Nisimoto et al.
BIOCHEMISTRY (2010)
Crystal structures of human Ero1α reveal the mechanisms of regulated and targeted oxidation of PDI
Kenji Inaba et al.
EMBO JOURNAL (2010)
Dual-specificity phosphatases: critical regulators with diverse cellular targets
Kate I. Patterson et al.
BIOCHEMICAL JOURNAL (2009)
Alterations of histone modifications by cobalt compounds
Qin Li et al.
CARCINOGENESIS (2009)
Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions
Caroline N. Mills et al.
MOLECULAR CANCER (2009)
Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1 alpha
Mei Y. Koh et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
William G. Kaelin et al.
MOLECULAR CELL (2008)
Reactive oxygen species activate the HIF-1α promoter via a functional NFκB site
Steve Bonello et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2
Utta Berchner-Pfannschmidt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels -: Evidence for an autoregulatory oxygen-sensing system
Daniel P. Stiehl et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Reactive oxygen species attenuate nitric-oxide-mediated hypoxia-inducible factor-1α stabilization
R Köhl et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Nox4 is critical for hypoxia-inducible factor 2-α transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma
JK Maranchie et al.
CANCER RESEARCH (2005)
Dual-specificity phosphatase DUSP1 protects overactivation of hypoxia-inducible factor 1 through inactivating ERK MAPK
CJ Liu et al.
EXPERIMENTAL CELL RESEARCH (2005)
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
RD Guzy et al.
CELL METABOLISM (2005)
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases
P Koivunen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Oxidative protein folding in eukaryotes: mechanisms and consequences
BP Tu et al.
JOURNAL OF CELL BIOLOGY (2004)
Hypoxia-induced activation of p38 mitogen-activated protein kinase and phosphatidylinositol 3′-kinase signaling pathways contributes to expression of interleukin 8 in human ovarian carcinoma cells
L Xu et al.
CLINICAL CANCER RESEARCH (2004)
Hypoxia up-regulates prolyl hydroxylase activity - A feedback mechansim that limits HIF-1 responses during reoxygenation
G D'Angelo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mitochondrial ROS initiate phosphorylation of p38 MAP kinase during hypoxia in cardiomyocytes
A Kulisz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2002)
A conserved family of prolyl-4-hydroxylases that modify HIF
RK Bruick et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)