期刊
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
卷 -, 期 -, 页码 -出版社
SPRINGER
DOI: 10.1007/s10840-023-01481-4
关键词
Atrial fibrillation; Remote monitoring; Anticoagulation; Cardiac implantable electronic device
This study aimed to evaluate the impact of a remote monitoring system on anticoagulation treatment in patients with atrial fibrillation (AF) who have cardiac implantable electronic devices. The results showed that despite intensive management through remote monitoring software, a substantial proportion of AF patients remained unanticoagulated. This highlights the need for improved clinical response pathways and an integrated care approach.
Background Remote monitoring (RM) can facilitate early detection of subclinical and symptomatic atrial fibrillation (AF), providing an opportunity to evaluate the need for stroke prevention therapies. We aimed to characterize the burden of RM AF alerts and its impact on anticoagulation of patients with device-detected AF.Methods Consecutive patients with a cardiac implantable electronic device, at least one AF episode, undergoing RM were included and assigned an estimated minimum CHA2DS2-VASc score based on age and device type. RM was provided via automated software system, providing rapid alert processing by device specialists and systematic, recurrent prompts for anticoagulation.Results From 7651 individual, 389,188 AF episodes were identified, 3120 (40.8%) permanent pacemakers, 2260 (29.5%) implantable loop recorders (ILRs), 987 (12.9%) implantable cardioverter defibrillators, 968 (12.7%) cardiac resynchronization therapy (CRT) defibrillators, and 316 (4.1%) CRT pacemakers. ILRs transmitted 48.8% of all AF episodes. At twelve-months, 3404 (44.5%) AF < 6 min, 1367 (17.9%) 6 min-6 h, 1206 (15.8%) 6-24 h, and 1674 (21.9%) >= 24 h. A minimum CHA(2)DS(2)-VASc score of 2 was assigned to 1704 (63.1%) of the patients with an AF episode of >= 6 h, 531 (31.2%) who were not anticoagulated at 12-months, and 1031 (61.6%) patients with an AF episode duration of >= 24 h, 290 (28.1%) were not anticoagulated.Conclusions Despite being intensively managed via RM software system incorporating cues for anticoagulation, a substantial proportion of patients with increased stroke risk remained unanticoagulated after a device-detected AF episode of significant duration. These data highlight the need for improved clinical response pathways and an integrated care approach to RM.
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