4.6 Article

A simple strategy for the efficient design of mitochondria-targeting NIR-II phototheranostics

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Engineering, Biomedical

Cationization to boost both type I and type II ROS generation for photodynamic therapy

Yuewen Yu et al.

Summary: In this study, a cationization molecular engineering strategy was used to enhance the generation of reactive oxygen species (ROS) for efficient photodynamic therapy (PDT). The cationization process improved the aggregation-induced emission (AIE) feature, promoted intersystem crossing (ISC) processes, and increased charge transfer and separation ability, leading to the efficient production of ROS, particularly hydroxyl and superoxide radicals. Additionally, the cationic AIE photosensitizers also exhibited specific cancer cell mitochondrial targeting capability, which further improved the efficacy of PDT.

BIOMATERIALS (2022)

Article Chemistry, Multidisciplinary

Aggregation-Induced Emission Nanoparticles for Single Near-Infrared Light-Triggered Photodynamic and Photothermal Antibacterial Therapy

Wentao Wang et al.

Summary: By synthesizing quaternary amine functionalized aggregation-induced emission (AIE) materials to produce singlet oxygen and heat, the nanoparticles selectively targeted Gram-positive and Gram-negative bacteria, exhibiting significant antibacterial performance.

ACS NANO (2022)

Article Chemistry, Multidisciplinary

Cationization-Enhanced Type I and Type II ROS Generation for Photodynamic Treatment of Drug-Resistant Bacteria

Shanshan Liu et al.

Summary: This article introduces a molecular cationization approach to enhance the generation of reactive oxygen species (ROS) by aggregation-induced emission (AIE) photosensitizers, especially type I ROS, for photodynamic treatment of drug-resistant bacteria.

ACS NANO (2022)

Article Chemistry, Multidisciplinary

Antibacterial Theranostic Agents with Negligible Living Cell Invasiveness: AIE-Active Cationic Amphiphiles Regulated by Alkyl Chain Engineering

Zeyan Zhuang et al.

Summary: This study designed a series of cationic pyridinium-substituted phosphindole oxide derivatives with aggregation-induced emission and investigated their bioaffinity for living mammal cells and pathogenic bacteria. An efficient theranostic agent with no cell invasiveness, good affinity for Gram-positive bacteria, and high inactivating effect was obtained. External application of this agent achieved reliable imaging effects and accelerated wound healing.

ACS NANO (2022)

Review Chemistry, Multidisciplinary

The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Zhijun Zhang et al.

Summary: Photo-driven theranostics, which integrate diagnostic imaging and therapeutic interventions, rely on the diverse excited-state energy conversions of theranostic agents. The applications of aggregation-induced emission luminogens (AIEgens) in this field have been extensively studied due to their favorable biocompatibility, tunable photophysical properties, unique theranostic features, and multimodal capabilities. This review summarizes the significant achievements of photo-driven theranostics based on AIEgens and elaborates on their diverse theranostic modalities.

CHEMICAL SOCIETY REVIEWS (2022)

Editorial Material Multidisciplinary Sciences

Mechanistic connotations of restriction of intramolecular motions (RIM)

Yujie Tu et al.

NATIONAL SCIENCE REVIEW (2021)

Review Engineering, Environmental

Recent advances in molecular oxygen activation via photocatalysis and its application in oxidation reactions

Qi Li et al.

Summary: This study discusses the feasibility of using photocatalysis technology to activate molecular oxygen and explores potential applications and activation mechanisms. It summarizes the methods of analyzing ROS, the application of activated molecular oxygen in oxidative reactions, and presents future research challenges and directions.

CHEMICAL ENGINEERING JOURNAL (2021)

Article Chemistry, Multidisciplinary

Enlarging Reservoir: High Absorption Coefficient Dyes Enable Synergetic Near Infrared-II Fluorescence Imaging and Near Infrared-I Photothermal Therapy

Yuanyuan Li et al.

Summary: This study proposes a strategy to optimize output signals by enlarging absorption reservoir and constructs strong light-absorbing systems using a large pi-conjugated DPP unit. Results show that TDADT nanoparticles are suitable for in vivo NIR-II imaging-guided cancer therapy and NIR-I photothermal therapy.

ADVANCED FUNCTIONAL MATERIALS (2021)

Review Chemistry, Multidisciplinary

Gathering brings strength: How organic aggregates boost disease phototheranostics

Ji Qi et al.

Summary: Organic phototheranostic agents show great promise in disease theranostics, especially in modulating fluorescence emission, photoacoustic/photothermal production, and photodynamic processes using energy dissipation pathways of Jablonski diagram. They play a significant role in biomedical applications by achieving efficient treatment and inspiring new insights into the linkage between aggregate science and the biomedical field.

AGGREGATE (2021)

Review Chemistry, Multidisciplinary

Structural and process controls of AIEgens for NIR-II theranostics

Shunjie Liu et al.

Summary: Aggregation-induced emission (AIE) is a cutting-edge technology for developing highly efficient NIR-II emitters and photothermal agents, with the optimization of multi-hierarchical structures and intramolecular motions balancing fluorescence imaging and photothermal therapy functions.

CHEMICAL SCIENCE (2021)

Article Chemistry, Multidisciplinary

An Acceptor-Donor-Acceptor Structured Small Molecule for Effective NIR Triggered Dual Phototherapy of Cancer

Zheng He et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Article Chemistry, Multidisciplinary

Constitutional Isomerization Enables Bright NIR-II AIEgen for Brain-Inflammation Imaging

Shunjie Liu et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

Article Chemistry, Multidisciplinary

A Phototheranostic Strategy to Continuously Deliver Singlet Oxygen in the Dark and Hypoxic Tumor Microenvironment

Jianhua Zou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Aggregation-Induced Emission (AIE): A Historical Perspective

Frank Wuerthner

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Chemistry, Multidisciplinary

Design of superior phototheranostic agents guided by Jablonski diagrams

Guangxue Feng et al.

CHEMICAL SOCIETY REVIEWS (2020)

Article Chemistry, Multidisciplinary

Molecular Motion in Aggregates: Manipulating TICT for Boosting Photothermal Theranostics

Shunjie Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Chemistry, Multidisciplinary

Semiconducting Perylene Diimide Nanostructure: Multifunctional Phototheranostic Nanoplatform

Zhen Yang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Review Medicine, Research & Experimental

Advances in nanomedicine for cancer starvation therapy

Shuangjiang Yu et al.

THERANOSTICS (2019)

Letter Cell Biology

Induction of autophagy by depolarization of mitochondria

Konstantin G. Lyamzaev et al.

AUTOPHAGY (2018)

Article Chemistry, Multidisciplinary

Recent Advances of Optical Imaging in the Second Near-Infrared Window

Kenry et al.

ADVANCED MATERIALS (2018)

Article Chemistry, Multidisciplinary

A Mitochondria-Targeted Cryptocyanine-Based Photothermogenic Photosensitizer

Hyo Sung Jung et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Engineering, Biomedical

Near-infrared fluorophores for biomedical imaging

Guosong Hong et al.

NATURE BIOMEDICAL ENGINEERING (2017)

Article Chemistry, Multidisciplinary

Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging

Kanyi Pu et al.

ADVANCED MATERIALS (2015)

Article Chemistry, Multidisciplinary

Fluorescence Imaging In Vivo at Wavelengths beyond 1500 nm

Shuo Diao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Multidisciplinary Sciences

Conductance of a single flexible molecular wire composed of alternating donor and acceptor units

Christophe Nacci et al.

NATURE COMMUNICATIONS (2015)

Review Food Science & Technology

Electron spin resonance spectroscopy for the study of nanomaterial-mediated generation of reactive oxygen species

Weiwei He et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2014)

Review Optics

Polymer solar cells

Gang Li et al.

NATURE PHOTONICS (2012)