4.2 Article

Presentation and outcomes of patients with multiple myeloma harboring gain or amplification of 1q21 and receiving novel agent therapies: results from a single-center study

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Summary: The amplification of 1q21 is a common cytogenetic abnormality in multiple myeloma, associated with poor response to standard therapies. The genes driving this amplification have not been fully studied, but potential candidates have been proposed as therapeutic targets. Understanding these genes is crucial for developing effective treatments for patients with 1q21 amplicon.
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