期刊
CLINICS IN CHEST MEDICINE
卷 36, 期 1, 页码 13-34出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccm.2014.10.002
关键词
Epidemiology; Nontuberculous mycobacteria; Pulmonary disease; Global
资金
- Division of Intramural Research, National Institutes of Allergy and Infectious Diseases, National Institutes of Health
Population-based data have documented a worldwide increase in the prevalence of human nontuberculous mycobacterial (NTM) infections since 2000. Mycobacterium avium complex is predominant in North America and East Asia, whereas in regions within Europe, M kansasii, M xenopi, and M malmoense are more common. Host factors important to the current epidemiology of NTM pulmonary disease include thoracic skeletal abnormalities, rheumatoid arthritis, and use of immunomodulatory drugs. Clustering of disease within families suggests a heritable genetic predisposition to disease susceptibility. Warm, humid environments with high atmospheric vapor pressure contribute to population risk.
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