相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Review of pharmacological options for the treatment of Chagas disease
Fernanda Lascano et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2022)
Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease
Ivan Beltran-Hortelano et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2022)
Coptisine induces autophagic cell death through down-regulation of PI3K/Akt/mTOR signaling pathway and up-regulation of ROS-mediated mitochondrial dysfunction in hepatocellular carcinoma Hep3B cells
So Young Kim et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2021)
Coptisine ameliorates DSS-induced ulcerative colitis via improving intestinal barrier dysfunction and suppressing inflammatory response
Yongfu Wang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2021)
Gut Microbiota-Mediated Transformation of Coptisine Into a Novel Metabolite 8-Oxocoptisine: Insight Into Its Superior Anti-Colitis Effect
Gaoxiang Ai et al.
FRONTIERS IN PHARMACOLOGY (2021)
In vitro study of the trypanocidal activity of anilinophenanthrolines against Trypanosoma cruzi
Aline Araujo Zuma et al.
PARASITOLOGY INTERNATIONAL (2021)
Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway
So Young Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds
Awet Alem Teklemichael et al.
MALARIA JOURNAL (2020)
Challenges in Chagas Disease Drug Development
Amanda F. Francisco et al.
MOLECULES (2020)
β-Eudesmol induces the expression of apoptosis pathway proteins in cholangiocarcinoma cell lines
Chisato Narahara et al.
JOURNAL OF RESEARCH IN MEDICAL SCIENCES (2020)
IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia
Clara Vasquez Velasquez et al.
PLOS NEGLECTED TROPICAL DISEASES (2019)
Coptisine, a natural alkaloid from Coptidis Rhizoma, inhibits plasmodium falciparum dihydroorotate dehydrogenase
Li Lang et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2018)
NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes
Osamu Tani et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts
Motohiro Nonaka et al.
MALARIA JOURNAL (2018)
Canonical PI3K gamma signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis
Maria C. Silva et al.
NATURE COMMUNICATIONS (2018)
Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase
Shankar Suman et al.
PLOS NEGLECTED TROPICAL DISEASES (2018)
Anti-inflammatory activity of coptisine free base in mice through inhibition of NF-κB and MAPK signaling pathways
Han-bin Chen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2017)
Identification of crude drugs in the Japanese pharmacopoeia using a DNA barcoding system
Xiaochen Chen et al.
SCIENTIFIC REPORTS (2017)
Demystifying traditional herbal medicine with modern approaches
Fu-Shuang Li et al.
NATURE PLANTS (2017)
Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase
Daniel Ken Inaoka et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells
Jiasi Wu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Coptisine Prevented IL-β-Induced Expression of Inflammatory Mediators in Chondrocytes
Kai Zhou et al.
INFLAMMATION (2016)
Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade
Manu De Rycker et al.
PLOS NEGLECTED TROPICAL DISEASES (2016)
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease
Xianxiu Wan et al.
PLOS PATHOGENS (2016)
Kampo Medicine: Evaluation of the Pharmacological Activity of 121 Herbal Drugs on GABAA and 5-HT3A Receptors
Katrin M. Hoffmann et al.
FRONTIERS IN PHARMACOLOGY (2016)
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage
Amanda Fortes Francisco et al.
SCIENTIFIC REPORTS (2016)
Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging
Amanda Fortes Francisco et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Coptisine attenuates obesity-related inflammation through LPS/TLR-4-mediated signaling pathway in Syrian golden hamsters
Zong-Yao Zou et al.
FITOTERAPIA (2015)
Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice
Romulo Dias Novaes et al.
PARASITOLOGY RESEARCH (2015)
Benznidazole/Itraconazole Combination Treatment Enhances Anti-Trypanosoma cruzi Activity in Experimental Chagas Disease
Tassiane Assiria Fontes Martins et al.
PLOS ONE (2015)
New Compound Sets Identified from High Throughput Phenotypic Screening Against Three Kinetoplastid Parasites: An Open Resource
Imanol Pena et al.
SCIENTIFIC REPORTS (2015)
Automated High-Content Assay for Compounds Selectively Toxic to Trypanosoma cruzi in a Myoblastic Cell Line
Julio Alonso-Padilla et al.
PLOS NEGLECTED TROPICAL DISEASES (2015)
Antitrypanosomal Activity of Fexinidazole Metabolites, Potential New Drug Candidates for Chagas Disease
Maria T. Bahia et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection
Michael D. Lewis et al.
CELLULAR MICROBIOLOGY (2014)
Historical Perspective of Traditional Indigenous Medical Practices: The Current Renaissance and Conservation of Herbal Resources
Si-Yuan Pan et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease
Ricardo Palmeiro-Roldan et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2014)
Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and development
Carolina B. Moraes et al.
SCIENTIFIC REPORTS (2014)
On Dihydroorotate Dehydrogenases and Their Inhibitors and Uses
Helene Munier-Lehmann et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
In vitro and in vivo trypanocidal activity of some benzimidazole derivatives against two strains of Trypanosoma cruzi
Dylan L. Diaz-Chiguer et al.
ACTA TROPICA (2012)
Real-time PCR strategy for parasite quantification in blood and tissue samples of experimental Trypanosoma cruzi infection
Sergio Caldas et al.
ACTA TROPICA (2012)
Critical importance of the de novo pyrimidine biosynthesis pathway for Trypanosoma cruzi growth in the mammalian host cell cytoplasm
Muneaki Hashimoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease
Fabiana S. Machado et al.
SEMINARS IN IMMUNOPATHOLOGY (2012)
Pathogenesis of Chagas' Disease: Parasite Persistence and Autoimmunity
Antonio R. L. Teixeira et al.
CLINICAL MICROBIOLOGY REVIEWS (2011)
Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression
Marta Lopez-Pelaez et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Chagas disease: 100 years after its discovery. A systemic review
Jose Rodrigues Coura et al.
ACTA TROPICA (2010)
Chagas disease: A Latin American health problem becoming a world health problem
Gabriel A. Schmunis et al.
ACTA TROPICA (2010)
Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery
Juliana Cheleski et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Acute toxicity of berberine and its correlation with the blood concentration in mice
Michael M. Kheir et al.
FOOD AND CHEMICAL TOXICOLOGY (2010)
Dendritc cells devoid of IL-10 induce protective immunity against the protozoan parasite Trypanosoma cruzi
Catalina D. Alba Soto et al.
VACCINE (2010)
Trypanosoma cruzi Targets Akt in Host Cells as an Intracellular Antiapoptotic Strategy
Marina V. Chuenkova et al.
SCIENCE SIGNALING (2009)
Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening
Esther Bettiol et al.
PLOS NEGLECTED TROPICAL DISEASES (2009)
Bioluminescent imaging of Trypanosoma cruzi infection
Kenneth V. Hyland et al.
INTERNATIONAL JOURNAL FOR PARASITOLOGY (2008)
Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88
MA Campos et al.
JOURNAL OF IMMUNOLOGY (2004)
Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells
S Mukherjee et al.
INFECTION AND IMMUNITY (2004)
Trypanosoma cruzi:: Phosphatidylinositol 3-kinase and protein kinase B activation is associated with parasite invasion
SE Wilkowsky et al.
EXPERIMENTAL CELL RESEARCH (2001)
Activation of host cell phosphatidylinositol 3-kinases by Trypanosoma cruzi infection
AG Todorov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Review: Drug therapy in Chinese traditional medicine
JT Cheng
JOURNAL OF CLINICAL PHARMACOLOGY (2000)
分享论文
