A case of severe paraquat poisoning treated by continuous hemodiafiltration without sequelae

BackgroundIn a suicide attempt, a 49-year-old male ingested pesticides. He arrived at the hospital restless and vomiting blue liquid. Case PresentationThe patient was diagnosed with paraquat poisoning at a lethal dose and experienced renal dysfunction during treatment. He underwent continuous hemodiafiltration (CHDF). Hemodialysis was temporarily initiated and found to improve renal function. He was discharged on day 36 in good condition. He remains well with only mild renal impairment and no pulmonary fibrosis, 240 days after the incident. The fatality rate of paraquat poisoning is approximately 80%, regardless of the treatment. Early hemodialysis combined with CHDF within 4 h has been reported to be effective. In this case, CHDF was initiated approximately 3 h after paraquat administration and showed a successful outcome. ConclusionCHDF should be performed as soon as possible to treat paraquat poisoning.

Automated summary

A 49-year-old male attempted suicide by ingesting pesticides and presented at the hospital with restlessness and vomiting blue liquid. He was diagnosed with paraquat poisoning at a lethal dose and experienced renal dysfunction. Continuous hemodiafiltration (CHDF) and temporary hemodialysis were initiated and resulted in improved renal function. The patient was discharged in good condition after 36 days and remains well with mild renal impairment and no pulmonary fibrosis 240 days after the incident. Early initiation of CHDF is crucial in treating paraquat poisoning.