☆ 4.4 Review

IgG4-related disease with kidney and lymph nodes involvement: a case-based review

RHEUMATOLOGY INTERNATIONAL (2023)

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Review Respiratory System

Thoracic manifestations of IgG4-related disease

Romain Muller et al.

Summary: IgG4-related disease is a rare systemic fibroinflammatory disease that can affect various organs, including the thoracic region. Diagnosing thoracic involvement requires a comprehensive approach, including clinical, biological, imaging, and histopathological evaluations. Steroids are recommended as the first-line treatment for this disease.

RESPIROLOGY (2023)

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Review Medicine, Research & Experimental

Clinical Perspectives on IgG4-Related Disease and Its Classification

Guy Katz et al.

Summary: Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibroinflammatory disease. The classification criteria provide a framework for diagnosis and ongoing research aims to determine the optimal long-term management of the disease.

ANNUAL REVIEW OF MEDICINE (2022)

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Review Gastroenterology & Hepatology

IgG4-related diseases of the digestive tract

J-Matthias Lohr et al.

Summary: IgG4-RD is a fibro-inflammatory disorder involving multiple organs, with common manifestations including autoimmune pancreatitis and IgG4-related cholangitis, presenting symptoms such as jaundice, weight loss, and abdominal pain. Diagnosis is based on histology, imaging, serology, other organ involvement, and response to therapy. Treatment mainly involves glucocorticoids, with disease flares common at low doses or after tapering.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2022)

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Article Cell Biology

IgG4-related disease is characterised by the overexpression of immunomodulatory proteins

Kshitij Arora et al.

Summary: Immunoglobulin 4-related disease (IgG4-RD) is characterized by increased numbers of immunomodulatory cells and up-regulation of immunomodulatory proteins, suggesting their significant role in the disease.

HISTOPATHOLOGY (2022)

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Review Endocrinology & Metabolism

Hypophysitis, the Growing Spectrum of a Rare Pituitary Disease

Fabienne Langlois et al.

Summary: Hypophysitis is inflammation of the pituitary gland that can be caused by various factors. Diagnosis is challenging and often requires detailed history, clinical examination, and pituitary biopsy. Treatment includes hormone replacement, careful observation, imaging follow-up, and in some cases, surgery, immunosuppressive therapy, and radiation.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

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Review Immunology

IgG4-Related Disease With Gastrointestinal Involvement: Case Reports and Literature Review

Xinhe Zhang et al.

Summary: IgG4-related disease is an immune-mediated chronic, systemic, and autoinflammatory disease that can affect various organs throughout the body. The most commonly affected areas are the pancreas and biliary system. This article reports two special cases involving atrophic gastritis and intestinal polyps, providing empirical and theoretical basis for clinical diagnosis and treatment.

FRONTIERS IN IMMUNOLOGY (2022)

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Editorial Material Medicine, General & Internal

IgG4-Related Ophthalmic Disease

Stephanie V. Sherman et al.

Summary: A 67-year-old man presented with swollen eyelids and proptosis in the ophthalmology clinic. Biopsy of the right lacrimal gland revealed a lymphoplasmacytic infiltrate with IgG4-positive plasma cells.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

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Article Pathology

IgG4-related Lymphadenopathy A Comparative Study of 41 Cases Reveals Distinctive Histopathologic Features

Jacob R. Bledsoe et al.

Summary: The presence of increased IgG4-positive plasma cells and IgG4/IgG ratio is not sensitive or specific for the diagnosis of IgG4-related lymphadenopathy, while most described morphologic patterns are nonspecific. Nodal involvement by IgG4-rich fibrosis or diffuse interfollicular expansion by IgG4-positive plasma cells are highly specific features of true IgG4-related lymphadenopathy. These findings provide a clinically meaningful approach for distinguishing IgG4-related lymphadenopathy from its mimics during lymph node evaluation by pathologists.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2021)

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Article Rheumatology

The 2019 American College of Rheumatology/European League Against Rheumatism Classification Criteria for IgG4-Related Disease

Zachary S. Wallace et al.

ARTHRITIS & RHEUMATOLOGY (2020)

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Review Medicine, General & Internal

Advances in the diagnosis and management of IgG4 related disease

Marco Lanzillotta et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

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Review Rheumatology

IgG4-related disease: an update on pathophysiology and implications for clinical care

Cory A. Perugino et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

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Review Rheumatology

New insights into IgG4-related disease: emerging new CD4+ T-cell subsets

Ryuta Kamekura et al.

CURRENT OPINION IN RHEUMATOLOGY (2019)

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Review Immunology

IgG4-related disease: review of the histopathologic features, differential diagnosis, and therapeutic approach

Jacob R. Bledsoe et al.

APMIS (2018)

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Article Multidisciplinary Sciences

Mast Cells Exhibiting Strong Cytoplasmic Staining for IgE and High Affinity IgE Receptor are Increased in IgG4-Related Disease

Kenji Nishida et al.

SCIENTIFIC REPORTS (2018)

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Article Rheumatology

Aberrant Expansion and Function of Follicular Helper T Cell Subsets in IgG4-Related Disease

Yu Chen et al.

ARTHRITIS & RHEUMATOLOGY (2018)

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Article Rheumatology

Circulating plasmablasts/plasma cells: a potential biomarker for IgG4-related disease

Wei Lin et al.

ARTHRITIS RESEARCH & THERAPY (2017)

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Article Rheumatology

IgG4-related disease in Italy: clinical features and outcomes of a large cohort of patients

C. Campochiaro et al.

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2016)

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Article Rheumatology

Rituximab for IgG4-related disease: a prospective, open-label trial

Mollie N. Carruthers et al.

ANNALS OF THE RHEUMATIC DISEASES (2015)

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Review Immunology

Immunology of IgG4-related disease

E. Della-Torre et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2015)

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Article Rheumatology

IgG4-Related Disease Clinical and Laboratory Features in One Hundred Twenty-Five Patients

Zachary S. Wallace et al.

ARTHRITIS & RHEUMATOLOGY (2015)

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Article Rheumatology

International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease

A. Khosroshahi et al.

ARTHRITIS & RHEUMATOLOGY (2015)

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Article Rheumatology

Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations

Zachary S. Wallace et al.

ANNALS OF THE RHEUMATIC DISEASES (2015)

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Article Allergy

Prevalence of atopy, eosinophilia, and IgE elevation in IgG4-related disease

E. Della Torre et al.

ALLERGY (2014)

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Article Pathology

IgG4-Related Disease

Vinay S. Mahajan et al.

Annual Review of Pathology-Mechanisms of Disease (2013)

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Article Rheumatology

Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011

Hisanori Umehara et al.

MODERN RHEUMATOLOGY (2012)

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Review Medicine, General & Internal

MECHANISMS OF DISEASE IgG4-Related Disease

John H. Stone et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

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Article Rheumatology

Prevalence of IgG4-Related Disease in Japan Based on Nationwide Survey in 2009

Kazushige Uchida et al.

INTERNATIONAL JOURNAL OF RHEUMATOLOGY (2012)

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Review Immunology

The birthday of a new syndrome: IgG4-related diseases constitute a clinical entity

Hiroki Takahashi et al.

AUTOIMMUNITY REVIEWS (2010)

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Article Urology & Nephrology

Clinicopathological characteristics of patients with IgG4-related tubulointerstitial nephritis

Takako Saeki et al.

KIDNEY INTERNATIONAL (2010)

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Article Gastroenterology & Hepatology

A new clinicopathological entity of IgG4-related autoimmune disease

T Kamisawa et al.

JOURNAL OF GASTROENTEROLOGY (2003)

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Article Gastroenterology & Hepatology

Idiopathic Tumefactive Chronic Pancreatitis: Clinical Profile, Histology, and Natural History After Resection

Dhiraj Yadav et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2003)

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